TITLE Potassium ion accumulation wo cleft
COMMENT
modified From DiFrancesco & Noble 1985 Phil Trans R Soc Lond 307:353-398
modified for Neuron by FE GANNIER
francois.gannier@univ-tours.fr (University of TOURS)
ENDCOMMENT
INCLUDE "Unit.inc"
INCLUDE "Volume.inc"
NEURON {
SUFFIX K_acc
USEION k READ ki, ik, ko WRITE ki, ko
RANGE ik, pf, kb
}
PARAMETER {
ik (mA/cm2)
kb = 4 (mM)
pf = 0.7 (/s)
}
STATE {
ki START 140 (mM)
ko START 4 (mM)
}
LOCAL ViF, VeF
INITIAL {
VERBATIM
ki = _ion_ki;
ko = _ion_ko;
ENDVERBATIM
VeF = (1e-3)*Ve*F/S
ViF = (1e-3)*Vi*F/S
}
BREAKPOINT {
: SOLVE state METHOD derivimplicit
SOLVE state METHOD cnexp
}
: Rq Ko = Kc
DERIVATIVE state {
ki' = -ik /ViF
ko' = ik /VeF -(0.001)*pf*(ko - kb)
}