: Delayed rectifier K+ channel
: from Durstewitz & Gabriel (2006), Cerebral Cortex
NEURON {
SUFFIX Kdr
USEION k READ ki, ko WRITE ik
RANGE gKdrbar, gk
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
gKdrbar= 0.0338 (mho/cm2) <0,1e9>
}
ASSIGNED {
v (mV)
ik (mA/cm2)
gk (mho/cm2)
ek (mV)
ki (mM)
ko (mM)
}
STATE {
n
}
INITIAL {
n = alf(v)/(alf(v)+bet(v))
}
BREAKPOINT {
SOLVE states METHOD derivimplicit
gk = gKdrbar*n*n*n*n
ek = 25*log(ko/ki)
ik = gk*(v-ek)
}
DERIVATIVE states {
n' = (1-n)*alf(v)-n*bet(v)
}
UNITSOFF
FUNCTION alf(v(mV)) (/ms) {
LOCAL va
va=v-13
if (fabs(va)<1e-04) {
alf = -0.018*(-25 - va*0.5)
}
else {
alf = -0.018*va/(-1+exp(-va/25))
}
}
FUNCTION bet(v(mV)) (/ms) {
LOCAL vb
vb=v-23
if (fabs(vb)<1e-04) {
bet = 0.0054*(12 - vb*0.5)
}
else {
bet = 0.0054*vb/(-1+exp(vb/12))
}
}
UNITSON