: from Durstewitz & Gabriel (2006), Cerebral Cortex
TITLE ampa synapse
NEURON {
POINT_PROCESS ampa
NONSPECIFIC_CURRENT i
RANGE g,a,b,gAMPAmax,tauD,tauF,util
}
UNITS {
(uS) = (microsiemens)
(nA) = (nanoamp)
(mV) = (millivolt)
}
PARAMETER {
tcon = .2 (ms)
tcoff = 1.0 (ms)
eampa = 0 (mV)
gAMPAmax = 0 (uS)
tauD = 800 (ms)
tauF = 800 (ms)
util= .3
}
ASSIGNED {
v (mV)
i (nA)
g (uS)
factor
}
INITIAL {
a=0
b=0
factor=tcon*tcoff/(tcoff-tcon)
}
STATE {
a
b
}
BREAKPOINT {
SOLVE states METHOD derivimplicit
g = b-a
i = gAMPAmax*g*(v-eampa)
}
DERIVATIVE states {
a' = -a/tcon
b' = -b/tcoff
}
NET_RECEIVE(wgt,R,u,tlast (ms),nspike) {
LOCAL x
if (nspike==0) { R=1 u=util }
else {
if (tauF>0) { u=util+(1-util)*u*exp(-(t-tlast)/tauF) }
if (tauD>0) { R=1+(R*(1-u)-1)*exp(-(t-tlast)/tauD) }
}
x=wgt*factor*R*u
state_discontinuity(a,a+x)
state_discontinuity(b,b+x)
tlast=t
nspike= nspike+1
}