TITLE gkcadend.mod
UNITS {
(uM) = (micro/liter)
(mM) = (milli/liter)
(mA) = (milliamp)
(mV) = (millivolt)
}
NEURON {
SUFFIX gkcadend
USEION ca READ cai
USEION k READ ek WRITE ik
RANGE gkcabar, ikca
GLOBAL cinf, cexp
}
STATE {
c
}
INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) }
PARAMETER {
celsius (degC)
dt (ms)
v (mV)
gkcabar = 0.013(mho/cm2)
ikca (ma/cm2)
ek
}
ASSIGNED {
ik (mA/cm2)
cai (mM)
cinf cexp
}
LOCAL tinc, q10, alpha, beta, sum
BREAKPOINT {
q10 = 3^((celsius - 20)/10)
tinc = -dt * q10
alpha = 0.1 * (cai / 0.01)
beta = 0.1
sum = alpha + beta
cinf = alpha/sum
cexp = 1 - exp(tinc*sum)
c = c + cexp*(cinf-c)
ikca = gkcabar * c * (v-ek)
ik = ikca
}
UNITSOFF
INITIAL {
alpha = 0.1 * (cai / 0.01)
beta = 0.1
sum = alpha + beta
cinf = alpha/sum
c = cinf
}