//cell parameter file // co-ordinate mode *relative *cartesian *asymmetric *lambda_warn // specifying constants, SI units // Plenz D, Aertsen A. Neuroscience. 1996 Feb;70(4):861-91 // J Neurosci 1994,14:4613-4638 says Cm=0.007-0.008, Rm 120-200kOhm*cm^2 ??? //*set_compt_param RM 0.95 //ohm*m^2 =10 kohm*cm^2 *set_compt_param RM 2 //ohm*m^2 //Avrama decreased from 3 to 2 fix timeconstants //*set_compt_param CM 0.01 //farads/m^2 *set_compt_param CM 0.007 //farads/m^2 //*set_compt_param RA 2 //ohm*m = 100 ohm*cm *set_compt_param RA 3 //ohm*m // DOPAMIN CASE also 80% GABA *set_compt_param EREST_ACT -0.061 //?? relative to zero?? // ELEAK is -0.063 without dopamin and -0.061 with dopamin // DOPAMIN CASE also 80% GABA *set_compt_param ELEAK -0.061 *start_cell /library/tert_dend // x, y, z or x=length if y and z=0 tert_dend none 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend2 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend3 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend4 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend5 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend6 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend7 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 tert_dend8 . 30 0 0 0.5 AMPA_channel 16 GABA_channel 24 // make distal dend with 8 compartments a prototype *makeproto /library/tert_dend *start_cell /library/sec_dend sec_dend none 37 0 0 0.75 AMPA_channel 8.65 GABA_channel 13 A_channel 00 sec_dend2 . 37 0 0 0.75 AMPA_channel 8.65 GABA_channel 13 A_channel 00 sec_dend3 . 37 0 0 0.75 AMPA_channel 8.65 GABA_channel 13 A_channel 00 sec_dend4 . 37 0 0 0.75 AMPA_channel 8.65 GABA_channel 13 A_channel 00 *makeproto /library/sec_dend *start_cell /library/prim_dend prim_dend none 45 0 0 1 AMPA_channel 5.333 GABA_channel 8.0 A_channel 90 Na_channel 0 K3132_channel 0 prim_dend2 . 45 0 0 1 AMPA_channel 5.333 GABA_channel 8.0 A_channel 90 Na_channel 0 K3132_channel 0 *makeproto /library/prim_dend *start_cell soma none 20 0 0 15 Na_channel 1149 K3132_channel 582 A_channel 333 K13_channel 1.46 AMPA_channel 0.8 GABA_channel 1.2 *compt /library/prim_dend primdend1 soma 45 0 0 1 primdend2 soma 45 0 0 1 primdend3 soma 45 0 0 1 *compt /library/sec_dend secdend1 primdend1/prim_dend2 37 0 0 0.75 secdend2 primdend1/prim_dend2 37 0 0 0.75 secdend3 primdend2/prim_dend2 37 0 0 0.75 secdend4 primdend2/prim_dend2 37 0 0 0.75 secdend5 primdend3/prim_dend2 37 0 0 0.75 secdend6 primdend3/prim_dend2 37 0 0 0.75 *compt /library/tert_dend tertdend1 secdend1/sec_dend4 30 0 0 0.5 tertdend2 secdend1/sec_dend4 30 0 0 0.5 tertdend3 secdend2/sec_dend4 30 0 0 0.5 tertdend4 secdend2/sec_dend4 30 0 0 0.5 tertdend5 secdend3/sec_dend4 30 0 0 0.5 tertdend6 secdend3/sec_dend4 30 0 0 0.5 tertdend7 secdend4/sec_dend4 30 0 0 0.5 tertdend8 secdend4/sec_dend4 30 0 0 0.5 tertdend9 secdend5/sec_dend4 30 0 0 0.5 tertdend10 secdend5/sec_dend4 30 0 0 0.5 tertdend11 secdend6/sec_dend4 30 0 0 0.5 tertdend12 secdend6/sec_dend4 30 0 0 0.5