TITLE Sodium persistent current for RD Traub, J Neurophysiol 89:909-921, 2003
COMMENT
Implemented by Maciej Lazarewicz 2003 (mlazarew@seas.upenn.edu)
ENDCOMMENT
INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) }
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
}
NEURON {
SUFFIX nap
USEION na READ ena WRITE ina
RANGE i, minf, mtau, gnap, gbar :, vhalf, k
}
PARAMETER {
gbar = 1e-4 (mho/cm2)
v ena (mV)
k = 5 (mV)
vhalf = -48 (mV)
}
ASSIGNED {
ina (mA/cm2)
i (mA/cm2)
minf (1)
mtau (ms)
gnap (mho/cm2)
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
gnap = gbar * m
ina = gnap * ( v - ena )
i = ina
}
INITIAL {
rate(v)
m = minf
}
DERIVATIVE states {
rate(v)
m' = ( minf - m ) / mtau
}
UNITSOFF
PROCEDURE rate(v (mV)) {
if (v < -67.5 ) {
minf = 0
} else{
minf = 1 / ( 1 + exp( ( vhalf - v ) / k ) )
}
if( v < -40.0 ) {
mtau = 100*(0.025 + 0.14 * exp( ( v + 40 ) / 10 ))
}else{
mtau = 100*(0.02 + 0.145 * exp( ( - v - 40 ) / 10 ))
}
}
UNITSON