//genesis // This scripts regulates the temporal modulation of the fibres. // Feedforward input modulated by Harsch-Robinson. // Intracolumnar feedback input regulated by membrane potential of L5P. // Intercolumnar feedback: to be implemented later. /*************** Feedforward input *******************/ // feedforward input from the Harsch-Robinson external stochastic process // kept this in main script // include Harsch-Robinson_modulation.g // Harsch_Robinson_modulation 20 0.05 // addmsg /HR_modulation/RC/diffamp /Excitatory_fibres/FF/FF_diffamp[] GAIN output // addmsg /HR_modulation/RC/diffamp /Inhibitory_fibres/FF/FF_diffamp[] GAIN output addmsg /HR_modulation/RC/diffamp /Excitatory_fibres/FF/diffamp[] PLUS output addmsg /HR_modulation/RC/diffamp /Inhibitory_fibres/FF/diffamp[] PLUS output /********** Intracolumnar feedback input **************/ // feedback input from L5P // As feedback signal, we use the continuous soma membrane potential instead the // discrete action potential timing. // Diffamps are used to covert Vm to values positive (set plus field) and to change their amplitude // (set gain field). // It is expected that this intracolumnar feedback will suffice to induce oscillations. // The delay of this feedback can be set by the delay field of the synapses. // The position of the feedback synapses can be tuned via Firing_rate_profile.g // Excitatory ce /L5P create diffamp soma/E_diffamp setfield soma/E_diffamp plus 0.08 minus 0 \ saturation 10e10 \ gain 10 addmsg soma soma/E_diffamp PLUS Vm // addmsg /L5P/solve soma/E_diffamp PLUS {findsolvefield /L5P/solve /L5P/soma Vm} // addmsg /L5P/soma/E_diffamp /Excitatory_fibres/FBintra/FBintra_diffamp[] GAIN output addmsg /L5P/soma/E_diffamp /Excitatory_fibres/FBintra/diffamp[] PLUS output addmsg soma/E_diffamp /output/{asc_name} SAVE output // Inhibitory ce /L5Ponlybasal // ce /L5P create diffamp soma/I_diffamp setfield soma/I_diffamp plus 0.08 minus 0 \ saturation 10e10 \ gain 10 addmsg soma soma/I_diffamp PLUS Vm // addmsg /L5P/solve soma/I_diffamp PLUS {findsolvefield /L5P/solve /L5P/soma Vm} // addmsg soma/I_diffamp /Inhibitory_fibres/FBintra/FBintra_diffamp[] GAIN output addmsg soma/I_diffamp /Inhibitory_fibres/FBintra/diffamp[] PLUS output addmsg soma/I_diffamp /output/{asc_name} SAVE output /********** Intercolumnar feedback input **************/ // Note that strictly speaking this input can be of the feedforward type !