//genesis
// This is a version of the modified L5P model intended for use in a network.
// It only creates the L5P neuron, without any further processing,
// input or output.
// The modifications imply cuttung the tuft and preventing backpropagation of the action potential.
include defaults.g
str name
//Make prototype channels and compartments in library
include ../L5P37C-notuft/L5P_const+axon+syn.g
if (!({exists /library }))
create neutral /library
end
disable /library
pushe library
//include L5P_chans.g
include ../L5P37C-notuft/L5P_chans_tab.g
include ../L5P37C-notuft/L5P_synchan.g
//include L5P_comps.g
//include L5P_comps+axon.g
include ../L5P37C-notuft/L5P_comps+axon+syn.g
pope
include ../L5P37C-notuft/DiffRm.g
include ../L5P37C-notuft/Hgradient.g
function create_L5Pnotuft (pathname, px, py, pz)
str pathname
float px, py, pz // the position
echo {pathname}
echo px = {px}, py = {py}, pz = {pz}
//Set up multicompartmental model in Hines solver mode based on reconstructed morphology
//and rotate axes
readcell ../L5P37C-notuft/DS1_141099_rot2_sc_defmesh_axon_notuft.p {pathname} // -hsolve
//rotcoord /L5P {-3.1415927/2} -x // does not work : gives segmentation violation
// the following trick works
foreach name ({el {pathname}/##[][TYPE=compartment]})
// echo {name}
rotcoord {name} {3.1415927/2} -x -fixkids
end
foreach name ({el {pathname}/##[]/##[]})
// echo {name}
rotcoord {name} {3.1415927/2} -x -fixkids
end
setfield {pathname}/axon[]/InNa Gbar {{getfield {pathname}/axon[0]/InNa Gbar} * 2}
setfield {pathname}/axon[]/KDr Gbar {{getfield {pathname}/axon[0]/KDr Gbar} * 2}
setfield {pathname}/soma/NaF Gbar {{getfield {pathname}/soma/NaF Gbar} * 2}
setfield {pathname}/soma/KDr Gbar {{getfield {pathname}/soma/KDr Gbar} * 10}
setfield {pathname} x {{getfield {pathname} x} + {px}} \
y {{getfield {pathname} y} + {py}} \
z {{getfield {pathname} z} + {pz}}
foreach name ({el {pathname}/#[]/#})
// echo {name}
setfield {name} x {{getfield {name} x} + {px}} \
y {{getfield {name} y} + {py}} \
z {{getfield {name} z} + {pz}}
end
foreach name ({el {pathname}/#[]})
// echo {name}
setfield {name} x {{getfield {name} x} + {px}} \
y {{getfield {name} y} + {py}} \
z {{getfield {name} z} + {pz}}
end
//Set up differential distributions of Rm and h-channels
//include ../L5P37C-notuft/DiffRm.g
//include ../L5P37C-notuft/Hgradient.g
DiffRm {pathname} 4.0 0.27 500e-6 50e-6
Hgradient {pathname} H 0.15 6.0 500e-6 50e-6
end
/*
// This is moved to ../Network/Network_make.g
/*
ce /L5P
// setup the hines solver
echo preparing hines solver...
create hsolve solve
ce solve
// if this is set then reset will NOT change Vm in Hines
setfield . path "../##[][TYPE=compartment]" comptmode 1 chanmode 5 // 4 // 5 // 3
//setfield . path "../##[][TYPE=compartment]" comptmode 1 chanmode 1 computeIm 1 // 5 // 4 // 5 // 3
call . SETUP
*/
/*
// because there is a bug with the graph window when plotting with hines solver
name = {findsolvefield /L5P/solve /L5P/soma Vm}
addmsg /L5P/solve /data1/DS1_141099 PLOT {name} *Soma_Vm *red
name = {findsolvefield /L5P/solve /L5P/axon[19] Vm}
addmsg /L5P/solve /data1/DS1_141099 PLOT {name} *Axon_Vm *blue
name = {findsolvefield /L5P/solve /L5P/p0b1b2b1b1b1b2b1b2b1b2b1b2b1b1b1b2b1b2b1b2b1b2b1b2b1b2b1b1[8] Vm}
addmsg /L5P/solve /data1/DS1_141099 PLOT {name} *Dend_Vm *black
*/