NEURON {
SUFFIX kv3_gp
USEION k READ ek WRITE ik
RANGE g, ik, an, bn, gbar
GLOBAL a1, a2, a3:, a4
GLOBAL b1, b2, b3
GLOBAL Cq10
}
UNITS {
(mV) = (millivolt)
(S) = (siemens)
(mA) = (milliamp)
}
PARAMETER {
gbar = 1 (S/cm2)
celsius (degC)
a1 = 0.05 (1/ms)
a2 = 8 (mV)
a3 = 8 (mV)
b1 = 0.07 (1/ms)
b2 = -12 (mV)
b3 = -15 (mV)
Cq10 = 3
}
ASSIGNED {
v (mV)
ek (mV)
g (S/cm2)
ik (mA/cm2)
an (1/ms)
bn (1/ms)
kf1 (1/ms)
kb1 (1/ms)
kf2 (1/ms)
kb2 (1/ms)
q10
}
STATE {
c
o
}
BREAKPOINT {
SOLVE kin METHOD sparse
g = gbar*o
ik = g*(v-ek)
}
INITIAL {
SOLVE kin STEADYSTATE sparse
}
KINETIC kin{
rates(v)
~ c <-> o (an, bn)
CONSERVE c+o=1
}
PROCEDURE rates(v(mV)) {
q10 = Cq10^((celsius-22 (degC))/10 (degC))
an = q10 * a1*exp((v-a2)/a3)
bn = q10 * b1*exp((v-b2)/b3)
kf1 = 2*an
kb1 = bn
kf2 = an
kb2 = 2*bn
}