TITLE high-voltage-activated calcium channel for GPe neuron
COMMENT
modeled by Gunay et al., 2008
implemented in NEURON by Kitano, 2011
ENDCOMMENT
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
(mM) = (milli/liter)
}
NEURON {
SUFFIX CaH
USEION ca READ cai,cao WRITE ica
RANGE gmax, iCaH
}
PARAMETER {
v (mV)
dt (ms)
cai (mM)
cao (mM)
gmax = 0.001 (mho/cm2)
iCaH = 0.0 (mA/cm2)
e = 130 (mV)
theta_m = -20.0 (mV)
k_m = 7.0 (mV)
taum = 0.2 (ms)
}
STATE {
m
}
ASSIGNED {
ica (mA/cm2)
minf
}
BREAKPOINT {
SOLVE states METHOD cnexp
ica = gmax*m*(v-e)
iCaH = ica
}
UNITSOFF
INITIAL {
settables(v)
m = minf
}
DERIVATIVE states {
settables(v)
m' = (minf - m)/taum
}
PROCEDURE settables(v) {
TABLE minf FROM -100 TO 100 WITH 400
minf = 1.0 / (1.0 + exp((theta_m - v)/k_m))
}
UNITSON