: Two state kinetic scheme for Potassium channel
: Contains four kinetic parameters and one max conductance parameter.
NEURON {
SUFFIX KCHANNEL
USEION k READ ek WRITE ik
RANGE g, gbar,a12,a21,z12,z21
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
(pS) = (picosiemens)
(um) = (micron)
}
PARAMETER {
gbar = 0 (pS/um2)
a12 = 0.01 (/ms)
a21 = 0.02 (/ms)
z12 = 0.01 (/mV)
z21 = 0.02 (/mV)
}
ASSIGNED {
v (mV)
ek (mV)
g (pS/um2)
ik (mA/cm2)
k12 (/ms)
k21 (/ms)
}
STATE { c o }
BREAKPOINT {
SOLVE states METHOD sparse
g = gbar*o
ik = (1e-4)*g*(v - ek)
}
INITIAL { SOLVE states STEADYSTATE sparse}
KINETIC states {
rates(v)
~c <-> o (k12,k21)
CONSERVE c+o=1
}
PROCEDURE rates(v(millivolt)) {
k12 = a12*exp(z12*v)
k21 = a21*exp(-z21*v)
}