####################################### # Juliane Gansert # # Last Modified: April 3rd, 2008 # # To be run with the software NETWORK # ####################################### # Assignment of the parameters and equations # for the compartments defined in TwoCells.cfg # This is for the case that the diamter of the # dendrites is d=5um. th__=2 #define Kd_mpower 4 Kd_minf=1/(1+exp(-(x+53+th__)/16)) Kd_mtau=1+6/(1+exp((x+53+th__)/16)) #define Na_mpower 3 #define Na_hpower 1 Na_minf=1/(1+exp(-(x+40+th__)/9)) Na_hinf=1/(1+exp((x+62+th__)/10)) Na_htau=1+11/(1+exp((x+62+th__)/10)) ################################################# # A lambda = 3162.28 um # 6 comps of length 100.00 um (total 600.00 um) # Comp taum = 40.00 msec # Comp area = 3141.59 um2 # Comp ga = 785.398 nS # Comp gm = 0.785 nS # Comp cm = 31.416 pF ################################################# A0_Cm=31.415926 # pF A0_Ga=785.398163 # nS A0_L_Gmax=0.785398 # nS A0_L_Erev=-54.300000 # mV A0_Na_Gmax=471.238897 # nS A0_Na_Erev=50 # mV A0_Na_mpower=Na_mpower A0_Na_minf=Na_minf(x) A0_Na_hpower=Na_hpower A0_Na_hinf=Na_hinf(x) A0_Na_htau=Na_htau(x) A0_Kd_Gmax=94.247779 # nS A0_Kd_Erev=-77.5 # mV A0_Kd_mpower=Kd_mpower A0_Kd_minf=Kd_minf(x) A0_Kd_mtau=Kd_mtau(x) A1_Cm=31.415926 # pF A1_Ga=785.398163 # nS A1_L_Gmax=0.785398 # nS A1_L_Erev=-54.300000 # mV A1_Na_Gmax=471.238897 # nS A1_Na_Erev=50 # mV A1_Na_mpower=Na_mpower A1_Na_minf=Na_minf(x) A1_Na_hpower=Na_hpower A1_Na_hinf=Na_hinf(x) A1_Na_htau=Na_htau(x) A1_Kd_Gmax=94.247779 # nS A1_Kd_Erev=-77.5 # mV A1_Kd_mpower=Kd_mpower A1_Kd_minf=Kd_minf(x) A1_Kd_mtau=Kd_mtau(x) A2_Cm=31.415926 # pF A2_Ga=785.398163 # nS A2_L_Gmax=0.785398 # nS A2_L_Erev=-54.300000 # mV A2_Na_Gmax=471.238897 # nS A2_Na_Erev=50 # mV A2_Na_mpower=Na_mpower A2_Na_minf=Na_minf(x) A2_Na_hpower=Na_hpower A2_Na_hinf=Na_hinf(x) A2_Na_htau=Na_htau(x) A2_Kd_Gmax=94.247779 # nS A2_Kd_Erev=-77.5 # mV A2_Kd_mpower=Kd_mpower A2_Kd_minf=Kd_minf(x) A2_Kd_mtau=Kd_mtau(x) A3_Cm=31.415926 # pF A3_Ga=785.398163 # nS A3_L_Gmax=0.785398 # nS A3_L_Erev=-54.300000 # mV A3_Na_Gmax=471.238897 # nS A3_Na_Erev=50 # mV A3_Na_mpower=Na_mpower A3_Na_minf=Na_minf(x) A3_Na_hpower=Na_hpower A3_Na_hinf=Na_hinf(x) A3_Na_htau=Na_htau(x) A3_Kd_Gmax=94.247779 # nS A3_Kd_Erev=-77.5 # mV A3_Kd_mpower=Kd_mpower A3_Kd_minf=Kd_minf(x) A3_Kd_mtau=Kd_mtau(x) A4_Cm=31.415926 # pF A4_Ga=785.398163 # nS A4_L_Gmax=0.785398 # nS A4_L_Erev=-54.300000 # mV A4_Na_Gmax=471.238897 # nS A4_Na_Erev=50 # mV A4_Na_mpower=Na_mpower A4_Na_minf=Na_minf(x) A4_Na_hpower=Na_hpower A4_Na_hinf=Na_hinf(x) A4_Na_htau=Na_htau(x) A4_Kd_Gmax=94.247779 # nS A4_Kd_Erev=-77.5 # mV A4_Kd_mpower=Kd_mpower A4_Kd_minf=Kd_minf(x) A4_Kd_mtau=Kd_mtau(x) A5_Cm=31.415926 # pF A5_Ga=785.398163 # nS A5_L_Gmax=0.785398 # nS A5_L_Erev=-54.300000 # mV A5_Na_Gmax=471.238897 # nS A5_Na_Erev=50 # mV A5_Na_mpower=Na_mpower A5_Na_minf=Na_minf(x) A5_Na_hpower=Na_hpower A5_Na_hinf=Na_hinf(x) A5_Na_htau=Na_htau(x) A5_Kd_Gmax=94.247779 # nS A5_Kd_Erev=-77.5 # mV A5_Kd_mpower=Kd_mpower A5_Kd_minf=Kd_minf(x) A5_Kd_mtau=Kd_mtau(x) ################################################# # PA lambda = 3162.28 um # 6 comps of length 100.00 um (total 600.00 um) # Comp taum = 40.00 msec # Comp area = 3141.59 um2 # Comp ga = 785.398 nS # Comp gm = 0.785 nS # Comp cm = 31.416 pF ################################################# PA0_Cm=31.415926 # pF PA0_Ga=785.398163 # nS PA0_L_Gmax=0.785398 # nS PA0_L_Erev=-54.300000 # mV PA0_Na_Gmax=471.238897 # nS PA0_Na_Erev=50 # mV PA0_Na_mpower=Na_mpower PA0_Na_minf=Na_minf(x) PA0_Na_hpower=Na_hpower PA0_Na_hinf=Na_hinf(x) PA0_Na_htau=Na_htau(x) PA0_Kd_Gmax=94.247779 # nS PA0_Kd_Erev=-77.5 # mV PA0_Kd_mpower=Kd_mpower PA0_Kd_minf=Kd_minf(x) PA0_Kd_mtau=Kd_mtau(x) PA1_Cm=31.415926 # pF PA1_Ga=785.398163 # nS PA1_L_Gmax=0.785398 # nS PA1_L_Erev=-54.300000 # mV PA1_Na_Gmax=471.238897 # nS PA1_Na_Erev=50 # mV PA1_Na_mpower=Na_mpower PA1_Na_minf=Na_minf(x) PA1_Na_hpower=Na_hpower PA1_Na_hinf=Na_hinf(x) PA1_Na_htau=Na_htau(x) PA1_Kd_Gmax=94.247779 # nS PA1_Kd_Erev=-77.5 # mV PA1_Kd_mpower=Kd_mpower PA1_Kd_minf=Kd_minf(x) PA1_Kd_mtau=Kd_mtau(x) PA2_Cm=31.415926 # pF PA2_Ga=785.398163 # nS PA2_L_Gmax=0.785398 # nS PA2_L_Erev=-54.300000 # mV PA2_Na_Gmax=471.238897 # nS PA2_Na_Erev=50 # mV PA2_Na_mpower=Na_mpower PA2_Na_minf=Na_minf(x) PA2_Na_hpower=Na_hpower PA2_Na_hinf=Na_hinf(x) PA2_Na_htau=Na_htau(x) PA2_Kd_Gmax=94.247779 # nS PA2_Kd_Erev=-77.5 # mV PA2_Kd_mpower=Kd_mpower PA2_Kd_minf=Kd_minf(x) PA2_Kd_mtau=Kd_mtau(x) PA3_Cm=31.415926 # pF PA3_Ga=785.398163 # nS PA3_L_Gmax=0.785398 # nS PA3_L_Erev=-54.300000 # mV PA3_Na_Gmax=471.238897 # nS PA3_Na_Erev=50 # mV PA3_Na_mpower=Na_mpower PA3_Na_minf=Na_minf(x) PA3_Na_hpower=Na_hpower PA3_Na_hinf=Na_hinf(x) PA3_Na_htau=Na_htau(x) PA3_Kd_Gmax=94.247779 # nS PA3_Kd_Erev=-77.5 # mV PA3_Kd_mpower=Kd_mpower PA3_Kd_minf=Kd_minf(x) PA3_Kd_mtau=Kd_mtau(x) PA4_Cm=31.415926 # pF PA4_Ga=785.398163 # nS PA4_L_Gmax=0.785398 # nS PA4_L_Erev=-54.300000 # mV PA4_Na_Gmax=471.238897 # nS PA4_Na_Erev=50 # mV PA4_Na_mpower=Na_mpower PA4_Na_minf=Na_minf(x) PA4_Na_hpower=Na_hpower PA4_Na_hinf=Na_hinf(x) PA4_Na_htau=Na_htau(x) PA4_Kd_Gmax=94.247779 # nS PA4_Kd_Erev=-77.5 # mV PA4_Kd_mpower=Kd_mpower PA4_Kd_minf=Kd_minf(x) PA4_Kd_mtau=Kd_mtau(x) PA5_Cm=31.415926 # pF PA5_Ga=785.398163 # nS PA5_L_Gmax=0.785398 # nS PA5_L_Erev=-54.300000 # mV PA5_Na_Gmax=471.238897 # nS PA5_Na_Erev=50 # mV PA5_Na_mpower=Na_mpower PA5_Na_minf=Na_minf(x) PA5_Na_hpower=Na_hpower PA5_Na_hinf=Na_hinf(x) PA5_Na_htau=Na_htau(x) PA5_Kd_Gmax=94.247779 # nS PA5_Kd_Erev=-77.5 # mV PA5_Kd_mpower=Kd_mpower PA5_Kd_minf=Kd_minf(x) PA5_Kd_mtau=Kd_mtau(x) ################################################# # Comp taum = 40.00 msec # Comp area = 1256.64 um2 # Comp ga = 20000.000 nS # Comp gm = 0.314 nS # Comp cm = 12.566 pF ################################################# S_Cm=12.566371 # pF S_Ga=20000.000000 # nS S_L_Gmax=0.314159 # nS S_L_Erev=-64.315641 ################################################# # Comp taum = 40.00 msec # Comp area = 1256.64 um2 # Comp ga = 20000.000 nS # Comp gm = 0.314 nS # Comp cm = 12.566 pF ################################################# PS_Cm=12.566371 # pF PS_Ga=20000.000000 # nS PS_L_Gmax=0.314159 # nS PS_L_Erev=-64.315641 # mV ################################################# # D lambda = 2236.07 um # 6 comps of length 100.00 um (total 600.00 um) # Comp taum = 40.00 msec # Comp area = 1570.80 um2 # Comp ga = 196.350 nS # Comp gm = 0.393 nS # Comp cm = 15.708 pF ################################################# D0_Cm=15.707963 # pF D0_Ga=196.349541 # nS D0_L_Gmax=0.392699 # nS D0_L_Erev=-64.315641 # mV D1_Cm=15.707963 # pF D1_Ga=196.349541 # nS D1_L_Gmax=0.392699 # nS D1_L_Erev=-64.315641 # mV D2_Cm=15.707963 # pF D2_Ga=196.349541 # nS D2_L_Gmax=0.392699 # nS D2_L_Erev=-64.315641 # mV D3_Cm=15.707963 # pF D3_Ga=196.349541 # nS D3_L_Gmax=0.392699 # nS D3_L_Erev=-64.315641 # mV D4_Cm=15.707963 # pF D4_Ga=196.349541 # nS D4_L_Gmax=0.392699 # nS D4_L_Erev=-64.315641 # mV D5_Cm=15.707963 # pF D5_Ga=196.349541 # nS D5_L_Gmax=0.392699 # nS D5_L_Erev=-64.315641 # mV ################################################# # PD lambda = 2236.07 um # 6 comps of length 100.00 um (total 600.00 um) # Comp taum = 40.00 msec # Comp area = 1570.80 um2 # Comp ga = 196.350 nS # Comp gm = 0.393 nS # Comp cm = 15.708 pF ################################################# PD0_Cm=15.707963 # pF PD0_Ga=196.349541 # nS PD0_L_Gmax=0.392699 # nS PD0_L_Erev=-64.315641 # mV PD1_Cm=15.707963 # pF PD1_Ga=196.349541 # nS PD1_L_Gmax=0.392699 # nS PD1_L_Erev=-64.315641 # mV PD2_Cm=15.707963 # pF PD2_Ga=196.349541 # nS PD2_L_Gmax=0.392699 # nS PD2_L_Erev=-64.315641 # mV PD3_Cm=15.707963 # pF PD3_Ga=196.349541 # nS PD3_L_Gmax=0.392699 # nS PD3_L_Erev=-64.315641 # mV PD4_Cm=15.707963 # pF PD4_Ga=196.349541 # nS PD4_L_Gmax=0.392699 # nS PD4_L_Erev=-64.315641 # mV PD5_Cm=15.707963 # pF PD5_Ga=196.349541 # nS PD5_L_Gmax=0.392699 # nS PD5_L_Erev=-64.315641 # mV D1_PD1_G_Ggap=20 # nS PD1_D1_G_Ggap=20 # nS # For 2ms a 2nA current is applied to the last segment # of the axon of cell 1. V if (t>4&&t<6) A5_Iext=2000; else A5_Iext=0;