/*
* Dendritic action potentials shape the computational
* properties of human layer 2/3 cortical neurons( Gidon et al., 2019)
*
* written by
* Athanasia Papoutsi and Albert Gidon
*/
objref imp
func get_Rin(){local x
x = $1
imp = new Impedance(x)
imp.loc(x)
imp.compute(0)
return imp.input(x)
}
proc biophys(){
celsius = 35
forall cm =0.45
forall Ra =100
//segment at least every 30 μm
forsec apical nseg = 1 + 2*int(L/30)
active_properties()
}
proc active_properties() {
Rm =37
forall insert pas
forall g_pas = 1/Rm/1000
forall e_pas = -74
forsec as{
//remove the passive properties from soma and axon
g_pas = 0
insert traub
// if the model is passive, leave all the passive
// leak as it is.
gNabar_traub = .1
gKbar_traub = .015 * 3
gLbar_traub = 1/Rm/1000
eL_traub = -74.0
eK_traub = -80
eNa_traub = 90
}
forall if(ismembrane("traub")) v_shft_traub = 50
}