from neuron import h
class Synapse_py3:
def __init__(self,source,target,section,weight = 1):
self.input = h.NetStim(0.5)
self.input.start = -10
self.input.number = 1
self.input.interval = 1e9
self.weight = weight
self.postsyns = {}
if (type(source) == type('s')):
sourcetype = source
#GOLGI
if sourcetype == 'PF':
if target.whatami == 'golgi2020':
# Make a parallel fiber synapse onto a Golgi cell
# Use deterministic synapses
self.whatami = "syn_PF2GoC_det"
self.postsyns['AMPA'] = [h.Golgi_PF_syn(0.5, sec=section)]
self.postsyns['AMPA'][0].tau_facil=10.8*5
self.postsyns['AMPA'][0].tau_rec=35.1
self.postsyns['AMPA'][0].tau_1=30
self.postsyns['AMPA'][0].gmax = 1200
self.postsyns['AMPA'][0].U=0.4
self.nc_syn = [h.NetCon(self.input,receptor[0],0,0.1,1) for receptor in self.postsyns.values()]
elif sourcetype == 'MF':
if target.whatami == 'golgi2020':
# Make a mossy fiber synapse onto a Golgi cell
# Use deterministic synapses
self.whatami = "syn_MF2GoC_det"
self.postsyns['AMPA'] = [h.Golgi_MF_syn(0.5, sec=section)]
self.postsyns['AMPA'][0].tau_facil=8
self.postsyns['AMPA'][0].tau_rec=5
self.postsyns['AMPA'][0].tau_1=1
self.postsyns['AMPA'][0].gmax = 1200
self.postsyns['AMPA'][0].U = 0.43
self.nc_syn = [h.NetCon(self.input,receptor[0],0,0.1,1) for receptor in self.postsyns.values()]
elif sourcetype == 'MF_nmda_B':
if target.whatami == 'golgi2020':
# Make a mossy fiber NMDAB onto a Golgi cell
# Use deterministic synapses*
self.whatami = "syn_MFB2GoC_det"
self.postsyns['NMDA'] = [h.PC_NMDA_NR2B(0.5, sec=section)]
self.postsyns['NMDA'][0].tau_facil=5
self.postsyns['NMDA'][0].tau_rec=8
self.postsyns['NMDA'][0].tau_1=1
self.postsyns['NMDA'][0].gmax = 10000
self.postsyns['NMDA'][0].U=0.43
#print 'nmda'
self.nc_syn = [h.NetCon(self.input,receptor[0],0,0.1,1) for receptor in self.postsyns.values()]
elif sourcetype == 'AA':
if target.whatami == 'golgi2020':
# Make a AA synapse onto a Golgi cell
# Use deterministic synapses*
self.whatami = "syn_AA2GoC_det"
self.postsyns['AMPA'] = [h.Golgi_PF_syn(0.7, sec=section)]
self.postsyns['AMPA'][0].tau_facil=54
self.postsyns['AMPA'][0].tau_rec=35.1
self.postsyns['AMPA'][0].tau_1=30
self.postsyns['AMPA'][0].gmax = 1200
self.postsyns['AMPA'][0].U=0.4
self.nc_syn = [h.NetCon(self.input,receptor[0],0,0.1,1) for receptor in self.postsyns.values()]
else:
print('SOURCE TYPE DOES NOT EXIST SOMETHING WRONG!!!!!!!!!')