// ******************************************************
//
// File generated by: neuroConstruct v1.7.1
//
// ******************************************************
{load_file("nrngui.hoc")}
// Initialising stopwatch for timing setup
{startsw()}
print ""
print "*****************************************************"
print ""
print " neuroConstruct generated NEURON simulation "
print " for project: https://github.com/Simon-at-Ely/NML2_Test/blob/master/AOB_MC_neuroConstruct/AOB_MC_neuroConstruct.ncx "
print ""
print " Description: "
print ""
print " Simulation Configuration: SimConfig: Default Simulation Configuration "
print " This is the default configuration of the Cell Groups, stimulations, plots, etc for this project "
print " "
print "*****************************************************"
strdef pwd
{system("pwd", pwd)}
print ""
print "Current working dir: ", pwd
objectvar allCells
{allCells = new List()}
// A flag to signal simulation was generated by neuroConstruct
{nC = 1}
// Getting hostname
objref strFuncs
{strFuncs = new StringFunctions()}
strdef host
{system("hostname", host)}
if (strFuncs.len(host)>0) {
strFuncs.left(host, strFuncs.len(host)-1)
} else {
host = "????"
}
// Simulation running in serial mode, setting default host id
{hostid = 0}
// Initializes random-number generator
{use_mcell_ran4(1)}
{mcell_ran4_init(640018898)}
//////////////////////////////////////////////////////////////////////
// Cell group 0: CellGroup_0 has cells of type: iMC1_cell_1_origin
//////////////////////////////////////////////////////////////////////
// Adding cell template file: iMitral_cell_Fig_10Hiii.hoc for cell group CellGroup_0
{ load_file("iMitral_cell_Fig_10Hiii.hoc") }
// Adding 1 cells of type iMitral_cell_Fig_10Hiii in region Regions_1
{n_CellGroup_0 = 1}
{n_CellGroup_0_local = 0 } // actual number created on this host
objectvar a_CellGroup_0[n_CellGroup_0]
proc addCell_CellGroup_0() {
strdef reference
sprint(reference, "CellGroup_0_%d", $1)
a_CellGroup_0[$1] = new iMitral_cell_Fig_10Hiii(reference, "iMitral_cell_Fig_10Hiii", "This is an AOB mitral cell that exhibited intrinsic oscillations reconstructed using Imaris confocal microscope software by Katja Watznauer cell split from iMC1 as: iMC1_cell_1 Imaris exported file name: 130918_MC_labelled_slice1_oscillating_MC_d1.ims.hoc")
allCells.append(a_CellGroup_0[$1])
}
for i = 0, n_CellGroup_0-1 {
addCell_CellGroup_0(i)
n_CellGroup_0_local = n_CellGroup_0_local +1
}
// Placing these cells in a region described by: Rectangular Box from point: (0.0, 0.0, 0.0) to (120.0, 50.0, 120.0)
// Packing has been generated by: Random: num: 1, edge: 1, overlap: 1, other overlap: 1
{a_CellGroup_0[0].position(90.86363,10.532186,85.20397)}
//////////////////////////////////////////////////////////////////////
// Setting initial parameters
//////////////////////////////////////////////////////////////////////
strdef simConfig
{simConfig = "Default Simulation Configuration"}
{celsius = 35.0}
// Note: the following values are from IonProperties in Cell
proc initialiseValues0() {
// Setting initial vals in cell group: CellGroup_0 which has 1 cells
// Giving all cells an initial potential of: -74.1
for i = 0, n_CellGroup_0-1 {
forsec a_CellGroup_0[i].all v = -74.1
}
}
objref fih0
{fih0 = new FInitializeHandler(0, "initialiseValues0()")}
proc initialiseValues1() {
for i = 0, n_CellGroup_0-1 {
forsec a_CellGroup_0[i].soma_group { eca = 80.0}
forsec a_CellGroup_0[i].dendrite_group { eca = 80.0}
forsec a_CellGroup_0[i].soma_group {
cai = 7.55E-5
cao = 2.4
}
forsec a_CellGroup_0[i].dendrite_group {
cai = 7.55E-5
cao = 2.4
}
forsec a_CellGroup_0[i].all { ena = 67.0}
forsec a_CellGroup_0[i].all { ek = -86.5}
}
}
objref fih1
{fih1 = new FInitializeHandler(1, "initialiseValues1()")}
//////////////////////////////////////////////////////////////////////
// Adding Network Connections
//////////////////////////////////////////////////////////////////////
//////////////////////////////////////////////////////////////////////
// Adding 0 stimulation(s)
//////////////////////////////////////////////////////////////////////
access iMitral_cell_Fig_10Hiii[0].filament_100000001_0
//////////////////////////////////////////////////////////////////////
// Settings for running the demo
//////////////////////////////////////////////////////////////////////
tstop = 60000.0
dt = 0.025
steps_per_ms = 40.0
//////////////////////////////////////////////////////////////////////
// Adding 1 plot(s)
//////////////////////////////////////////////////////////////////////
// This code pops up a plot of a_CellGroup_0[0].filament_100000001_0.v(0.04017303)
objref CellGroup_0_v
CellGroup_0_v = new Graph(0)
{CellGroup_0_v.size(0, tstop,-90.0,50.0)}
{CellGroup_0_v.view(0, -90.0, tstop, 140.0, 80, 330, 330, 250)}
{
CellGroup_0_v.addexpr("a_CellGroup_0[0].filament_100000001_0.v", "a_CellGroup_0[0].filament_100000001_0.v(0.04017303)", 1, 1, 0.8, 0.9, 2)
graphList[0].append(CellGroup_0_v)
}
//////////////////////////////////////////////////////////////////////
// This will run a full simulation of 2400001 steps when the hoc file is executed
//////////////////////////////////////////////////////////////////////
// Recording 0 variable(s)
objref v_time
objref f_time
objref propsFile
// Single simulation run...
strdef date
// Note: not showing date/time of start/stop of simulation. This requires Cygwin to be installed// which includes the "date" unix command. Install under c:\cygwin
setuptime = stopsw()
print "Setup time for simulation: ",setuptime," seconds"
{currenttime = startsw()}
//////////////////////////////////////////////////////////////////////
// Main run statement
//////////////////////////////////////////////////////////////////////
{run()}
{realruntime = startsw() - currenttime}
print "Finished simulation in ", realruntime ,"seconds"
// This code pops up a simple Run Control
{
xpanel("RunControl", 0)
v_init = -60.0
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
t = 0
xvalue("t","t", 2 )
tstop = 60000.0
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 0.025
xvalue("dt","dt", 1,"setdt()", 0, 1 )
xpanel(80,80)
}