/* Template of a simple/single fs basket cell, conceptual model of somatic cell Based on the Destexhe-van Elburg model and parameters */ load_file("nrngui.hoc") load_file("presets_WT1.hoc") begintemplate fast_spiking public soma,Dend,connections,netcon,position,x,y,z,f1,geometry,biophys,Area create soma access soma external ra, c_m, g_passive, ENa_fs, EK_fs, GK_fs, GNa_fs, v_rest_fs//fs normal parameters external ENa_pyr, EK_pyr,GK_pyr_s,GNa_pyr_s,ghd // pyram parameters (Boergers Kopell) objref connections,netcon proc init(){ create soma connections=new List() netcon=new List() geometry() biophys() } proc geometry(){ soma { L=20 diam=20 nseg=1 } } proc biophys(){ soma { //all the parameters vlues in presets_WT1.hoc Ra = ra cm = c_m //Insert Passive Current insert pas g_pas = g_passive e_pas = v_rest_fs //insert hh insert KPyr gbar_KPyr=GK_pyr_s ek=EK_pyr // HH-style sodium channel insert NaPyr gbar_NaPyr=GNa_pyr_s ena=ENa_pyr /* insert hd //h current ghdbar_hd=ghd vhalfl_hd=-73 ehd_hd=-30 */ //Insert Potassium Current /*insert KFS gbar_KFS=GK_fs ek_KFS=EK_fs //Insert Sodium Current insert NaFS gbar_NaFS=GNa_fs ena_NaFS=ENa_fs*/ //Classical Inward Rectifier Non_Inactivating (IRK2) //insert kir2fs //gbar_kir2fs=0.0007 /*insert hh1 gkbar_hh1=GK_pyr_s ek=EK_pyr gnabar_hh1=GNa_pyr_s ena=ENa_pyr gl_hh1=g_passive */ } } func Area(){local a access soma a=area(0.5) return a } access soma endtemplate fast_spiking obfunc create_FS(){local ncell localobj List_cells ncell=$2 $o1.remove_all() List_cells=$o1 for i=0, ncell-1{ List_cells.append(new fast_spiking()) } return List_cells } /* objref fs,Syn_Gaba fs=new List() create_FS(fs,1) proc put_Gaba_syn(){ Syn_Gaba=new List() for i=0, $o1.count()-1{ Syn_Gaba.append(new SynGABA($o1.o(i),0.6)) Syn_Gaba.o(i).put_syn($o1.o(i)) } } put_Gaba_syn(fs) */