TITLE Id and Ir currents of the Huber-Braun Model
: Braun et al. Int J Bifurcation and Chaos 8(5):881-889 (1998)
: Fast Na+ and K+ currents responsible for action potentials
:
: Written by Patricio Orio, Jul 2006
:
NEURON {
SUFFIX dr
USEION na READ ena WRITE ina
USEION k READ ek WRITE ik
RANGE gd, gr
RANGE td, tr
}
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
PARAMETER {
gd = 0.0015 (mho/cm2)
gr = 0.002 (mho/cm2)
V0d = -25 (mV)
V0r = -25 (mV)
sd = 0.25 (/mV)
sr = 0.25 (/mV)
tr = 2 (ms)
}
STATE {
ad ar
}
ASSIGNED {
celsius (degC)
ina (mA/cm2)
ik (mA/cm2)
v (mV)
ena (mV)
ek (mV)
rho (1)
}
INITIAL {
rho = 1.3^((celsius - 25 (degC))/10(degC))
ar = 1/(1+exp(-sr*(v - V0r)))
ad = 1/(1+exp(-sd*(v - V0d)))
}
BREAKPOINT {
SOLVE states METHOD cnexp
rho = 1.3^((celsius - 25 (degC))/10(degC))
ad = 1/(1+exp(-sd*(v - V0d)))
ina = rho * gd * ad * (v - ena)
ik = rho * gr * ar * (v - ek)
}
DERIVATIVE states {
LOCAL phi, arinf
phi = 3^((celsius - 25 (degC))/ 10 (degC))
arinf = 1/(1+exp(-sr*(v - V0r)))
ar' = phi*(arinf - ar)/tr
}