# HH-ext.ode: an XppAut file for the Hodgkin-Huxley equations # + strength of external electrical field # time in msec, voltage in mV and frequency in Hz # initial conditions init V=0, m=0.052, h=0.596, n=0.317 # the parameters param Vext=8, iapp=1, freq=0.3 param VNa=115,VK=-12,VL=10.599, gNa=120 param gK=36, gL=0.3, cm=1 # time constants and steady state functions for gating variables am(v)=0.1*(25-v)/(exp((25-v)/10)-1) bm(v)=4*exp(-v/18) ah(v)=0.07*exp(-v/20) bh(v)=1/(exp((30-v)/10)+1) an(v)=0.01*(10-v)/(exp((10-v)/10)-1) bn(v)=0.125*exp(-v/80) vex(t)=vext*(sin(2*pi*(freq/1000)*t)) ik=gk*n^4*(v+vex(t)-vk) ina=gna*m^3*h*(v+vex(t)-vna) il=gl*(v+vex(t)-vl) # the equations v'=(-ik-ina-il+iapp)/cm m'=(am(v)*(1-m)-bm(v)*m) n'=(an(v)*(1-n)-bn(v)*n) h'=(ah(v)*(1-h)-bh(v)*h) aux vex=vex(t) # set xpp parameters @ total=25000, xp=t, yp=v, xlo=0, xhi=25000, ylo=-20, yhi=120, bounds=10000000, dt=0.01 @ maxstor=10000000 done