This is the readme for the models associated with the paper: Handy G, Taheri M, White JA, Borisyuk A (2017) Mathematical investigation of IP3-dependent calcium dynamics in astrocytes. J Comput Neurosci These MATLAB and XPP files were contributed by G Handy. Use example_ca_sim_TH.m to reproduce calcium simulations found in Fig. 2 Use autoRespTypeDetection_TH.m to generate calcium responses resulting from multiple (or all 600) underlying IP3 traces, as well as characterize those calcium and IP3 traces (in terms of, for example, amplitude, total duration, area under the curves, etc.). Use ca_bifurcation_xpp.ode with XPPAUT to reproduce the bifurcation diagrams found J. Computation Neuroscience (submitted) Supporting_Functions contains all necessary functions to run the simulations. Histogram_Figures contains the data base of calcium response types distributions for a range of parameter values (original figures can be found in J. Computation Neuroscience (submitted)) Hopefully you have found this code helpful! --Marsa Taheri and Gregory Handy