This directory contains the Leech Heart Interneuron Timing Circuit Model and Tutorial by Andrew Hill, Steve Van Hooser, and Ron Calabrese. To run the tutorial, you'll need three items, two of which are in this directory: 1) The GENESIS neural simulator, which can be obtained at: http://www.bbb.caltech.edu/GENESIS 2) Extensions to GENESIS (leech-libraries) 3) The tutorial files (leech-tutorial) You need to make some extensions to GENESIS before you can run the model. You can either compile the libraries on your own computer and add them to your GENESIS program (follow the instructions in the README file inside the leech-libraries directory), or grab a pre-compiled GENESIS if one is available for your platform. A pre-compiled GENESIS for PC Linux is available on this CD (genesis-linux.bin), and more may be available on the Calabrese Lab website (http://calabreselx.biology.emory.edu/software). Instructions for running the model are contained in the README file in the leech-tutorial archive. Briefly, type "{genesis} tutorial.g" in the leech-tutorial directory, where {genesis} is the name of your GENESIS application. Updates to the tutorial and model will be available on the Calabrese Lab website (http://calabreselx.biology.emory.edu/software).