:Comment :
:Reference : : Kole,Hallermann,and Stuart, J. Neurosci. 2006
NEURON {
SUFFIX Ih
NONSPECIFIC_CURRENT ihcn
RANGE gbar, g, ihcn, shift1, shift2, shift3, shift4, shift5, shift6
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gbar = 0.00001 (S/cm2)
ehcn = -45.0 (mV)
shift1 = 154.9
shift2 = 11.9
shift3 = 0
shift4 = 33.1
shift5 = 6.43
shift6 = 193
}
ASSIGNED {
v (mV)
ihcn (mA/cm2)
g (S/cm2)
mInf
mTau
mAlpha
mBeta
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gbar*m
ihcn = g*(v-ehcn)
}
DERIVATIVE states {
rates()
m' = (mInf-m)/mTau
}
INITIAL{
rates()
m = mInf
}
PROCEDURE rates(){
UNITSOFF
if(v == -shift1){
v = v + 0.0001
}
if(shift4 == 0){
shift4 = shift4 + 0.0001
}
if(shift2 == 0){
shift2 = shift2 + 0.0001
}
mAlpha = 0.001*(shift5)*(v+shift1)/(exp((v+shift1)/(shift2))-1)
mBeta = 0.001*(shift6)*exp((v+shift3)/(shift4))
mInf = mAlpha/(mAlpha + mBeta)
mTau = 1/(mAlpha + mBeta)
UNITSON
}