/* Created by Language version: 7.7.0 */
/* VECTORIZED */
#define NRN_VECTORIZED 1
#include <stdio.h>
#include <stdlib.h>
#include <math.h>
#include "scoplib_ansi.h"
#undef PI
#define nil 0
#include "md1redef.h"
#include "section.h"
#include "nrniv_mf.h"
#include "md2redef.h"
 
#if METHOD3
extern int _method3;
#endif

#if !NRNGPU
#undef exp
#define exp hoc_Exp
extern double hoc_Exp(double);
#endif
 
#define nrn_init _nrn_init__tonic
#define _nrn_initial _nrn_initial__tonic
#define nrn_cur _nrn_cur__tonic
#define _nrn_current _nrn_current__tonic
#define nrn_jacob _nrn_jacob__tonic
#define nrn_state _nrn_state__tonic
#define _net_receive _net_receive__tonic 
#define kin kin__tonic 
#define rates rates__tonic 
 
#define _threadargscomma_ _p, _ppvar, _thread, _nt,
#define _threadargsprotocomma_ double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt,
#define _threadargs_ _p, _ppvar, _thread, _nt
#define _threadargsproto_ double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt
 	/*SUPPRESS 761*/
	/*SUPPRESS 762*/
	/*SUPPRESS 763*/
	/*SUPPRESS 765*/
	 extern double *getarg();
 /* Thread safe. No static _p or _ppvar. */
 
#define t _nt->_t
#define dt _nt->_dt
#define g _p[0]
#define e_gaba _p[1]
#define i _p[2]
#define a _p[3]
#define b _p[4]
#define o _p[5]
#define c _p[6]
#define Do _p[7]
#define Dc _p[8]
#define v _p[9]
#define _g _p[10]
 
#if MAC
#if !defined(v)
#define v _mlhv
#endif
#if !defined(h)
#define h _mlhh
#endif
#endif
 
#if defined(__cplusplus)
extern "C" {
#endif
 static int hoc_nrnpointerindex =  -1;
 static Datum* _extcall_thread;
 static Prop* _extcall_prop;
 /* external NEURON variables */
 /* declaration of user functions */
 static void _hoc_rates(void);
 static int _mechtype;
extern void _nrn_cacheloop_reg(int, int);
extern void hoc_register_prop_size(int, int, int);
extern void hoc_register_limits(int, HocParmLimits*);
extern void hoc_register_units(int, HocParmUnits*);
extern void nrn_promote(Prop*, int, int);
extern Memb_func* memb_func;
 
#define NMODL_TEXT 1
#if NMODL_TEXT
static const char* nmodl_file_text;
static const char* nmodl_filename;
extern void hoc_reg_nmodl_text(int, const char*);
extern void hoc_reg_nmodl_filename(int, const char*);
#endif

 extern void _nrn_setdata_reg(int, void(*)(Prop*));
 static void _setdata(Prop* _prop) {
 _extcall_prop = _prop;
 }
 static void _hoc_setdata() {
 Prop *_prop, *hoc_getdata_range(int);
 _prop = hoc_getdata_range(_mechtype);
   _setdata(_prop);
 hoc_retpushx(1.);
}
 /* connect user functions to hoc names */
 static VoidFunc hoc_intfunc[] = {
 "setdata_tonic", _hoc_setdata,
 "rates_tonic", _hoc_rates,
 0, 0
};
 /* declare global and static user variables */
 /* some parameters have upper and lower limits */
 static HocParmLimits _hoc_parm_limits[] = {
 0,0,0
};
 static HocParmUnits _hoc_parm_units[] = {
 "g_tonic", "siemens/cm2",
 "e_gaba_tonic", "millivolt",
 "i_tonic", "milliampere",
 "a_tonic", "/ms",
 "b_tonic", "/ms",
 0,0
};
 static double c0 = 0;
 static double delta_t = 0.01;
 static double o0 = 0;
 /* connect global user variables to hoc */
 static DoubScal hoc_scdoub[] = {
 0,0
};
 static DoubVec hoc_vdoub[] = {
 0,0,0
};
 static double _sav_indep;
 static void nrn_alloc(Prop*);
static void  nrn_init(_NrnThread*, _Memb_list*, int);
static void nrn_state(_NrnThread*, _Memb_list*, int);
 static void nrn_cur(_NrnThread*, _Memb_list*, int);
static void  nrn_jacob(_NrnThread*, _Memb_list*, int);
 
static int _ode_count(int);
static void _ode_map(int, double**, double**, double*, Datum*, double*, int);
static void _ode_spec(_NrnThread*, _Memb_list*, int);
static void _ode_matsol(_NrnThread*, _Memb_list*, int);
 
#define _cvode_ieq _ppvar[0]._i
 static void _ode_matsol_instance1(_threadargsproto_);
 /* connect range variables in _p that hoc is supposed to know about */
 static const char *_mechanism[] = {
 "7.7.0",
"tonic",
 "g_tonic",
 "e_gaba_tonic",
 0,
 "i_tonic",
 "a_tonic",
 "b_tonic",
 0,
 "o_tonic",
 "c_tonic",
 0,
 0};
 
extern Prop* need_memb(Symbol*);

static void nrn_alloc(Prop* _prop) {
	Prop *prop_ion;
	double *_p; Datum *_ppvar;
 	_p = nrn_prop_data_alloc(_mechtype, 11, _prop);
 	/*initialize range parameters*/
 	g = 0.001;
 	e_gaba = -80;
 	_prop->param = _p;
 	_prop->param_size = 11;
 	_ppvar = nrn_prop_datum_alloc(_mechtype, 1, _prop);
 	_prop->dparam = _ppvar;
 	/*connect ionic variables to this model*/
 
}
 static void _initlists();
  /* some states have an absolute tolerance */
 static Symbol** _atollist;
 static HocStateTolerance _hoc_state_tol[] = {
 0,0
};
 static void _thread_cleanup(Datum*);
 extern Symbol* hoc_lookup(const char*);
extern void _nrn_thread_reg(int, int, void(*)(Datum*));
extern void _nrn_thread_table_reg(int, void(*)(double*, Datum*, Datum*, _NrnThread*, int));
extern void hoc_register_tolerance(int, HocStateTolerance*, Symbol***);
extern void _cvode_abstol( Symbol**, double*, int);

 void _tonic_reg() {
	int _vectorized = 1;
  _initlists();
 	register_mech(_mechanism, nrn_alloc,nrn_cur, nrn_jacob, nrn_state, nrn_init, hoc_nrnpointerindex, 3);
  _extcall_thread = (Datum*)ecalloc(2, sizeof(Datum));
 _mechtype = nrn_get_mechtype(_mechanism[1]);
     _nrn_setdata_reg(_mechtype, _setdata);
     _nrn_thread_reg(_mechtype, 0, _thread_cleanup);
 #if NMODL_TEXT
  hoc_reg_nmodl_text(_mechtype, nmodl_file_text);
  hoc_reg_nmodl_filename(_mechtype, nmodl_filename);
#endif
  hoc_register_prop_size(_mechtype, 11, 1);
  hoc_register_dparam_semantics(_mechtype, 0, "cvodeieq");
 	hoc_register_cvode(_mechtype, _ode_count, _ode_map, _ode_spec, _ode_matsol);
 	hoc_register_tolerance(_mechtype, _hoc_state_tol, &_atollist);
 	hoc_register_var(hoc_scdoub, hoc_vdoub, hoc_intfunc);
 	ivoc_help("help ?1 tonic /Users/agmccrei/Google Drive/HayLab/Microcircuit/Test_Ih_Integration/mod/x86_64/tonic.mod\n");
 hoc_register_limits(_mechtype, _hoc_parm_limits);
 hoc_register_units(_mechtype, _hoc_parm_units);
 }
static int _reset;
static char *modelname = "";

static int error;
static int _ninits = 0;
static int _match_recurse=1;
static void _modl_cleanup(){ _match_recurse=1;}
static int rates(_threadargsprotocomma_ double);
 extern double *_nrn_thread_getelm();
 
#define _MATELM1(_row,_col) *(_nrn_thread_getelm(_so, _row + 1, _col + 1))
 
#define _RHS1(_arg) _rhs[_arg+1]
  
#define _linmat1  1
 static int _spth1 = 1;
 static int _cvspth1 = 0;
 
static int _ode_spec1(_threadargsproto_);
/*static int _ode_matsol1(_threadargsproto_);*/
 static int _slist1[2], _dlist1[2]; static double *_temp1;
 static int kin();
 
static int kin (void* _so, double* _rhs, double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt)
 {int _reset=0;
 {
   double b_flux, f_flux, _term; int _i;
 {int _i; double _dt1 = 1.0/dt;
for(_i=1;_i<2;_i++){
  	_RHS1(_i) = -_dt1*(_p[_slist1[_i]] - _p[_dlist1[_i]]);
	_MATELM1(_i, _i) = _dt1;
      
} }
 rates ( _threadargscomma_ v ) ;
   /* ~ o <-> c ( b , a )*/
 f_flux =  b * o ;
 b_flux =  a * c ;
 _RHS1( 1) -= (f_flux - b_flux);
 
 _term =  b ;
 _MATELM1( 1 ,1)  += _term;
 _term =  a ;
 _MATELM1( 1 ,0)  -= _term;
 /*REACTION*/
   /* o + c = 1.0 */
 _RHS1(0) =  1.0;
 _MATELM1(0, 0) = 1;
 _RHS1(0) -= c ;
 _MATELM1(0, 1) = 1;
 _RHS1(0) -= o ;
 /*CONSERVATION*/
   } return _reset;
 }
 
static int  rates ( _threadargsprotocomma_ double _lv ) {
   double _lx , _ly ;
  _lx = 0.1 * ( _lv + 20.0 ) ;
   if ( fabs ( _lx ) > 1e-6 ) {
     a = ( 50.0 * _lx ) / ( 1.0 - exp ( - _lx ) ) ;
     }
   else {
     a = 0.25 * ( pow( _lv , 2.0 ) + ( 20.0 * _lv ) + 200.0 ) ;
     }
   _ly = - 0.08 * ( _lv - 10.0 ) ;
   if ( fabs ( _lx ) > 1e-6 ) {
     b = ( 20.0 * _ly ) / ( 1.0 - exp ( - _ly ) ) ;
     }
   else {
     b = - 0.064 * ( pow( _lv , 2.0 ) - ( 45.0 * _lv ) + 37.5 ) ;
     }
     return 0; }
 
static void _hoc_rates(void) {
  double _r;
   double* _p; Datum* _ppvar; Datum* _thread; _NrnThread* _nt;
   if (_extcall_prop) {_p = _extcall_prop->param; _ppvar = _extcall_prop->dparam;}else{ _p = (double*)0; _ppvar = (Datum*)0; }
  _thread = _extcall_thread;
  _nt = nrn_threads;
 _r = 1.;
 rates ( _p, _ppvar, _thread, _nt, *getarg(1) );
 hoc_retpushx(_r);
}
 
/*CVODE ode begin*/
 static int _ode_spec1(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {int _reset=0;{
 double b_flux, f_flux, _term; int _i;
 {int _i; for(_i=0;_i<2;_i++) _p[_dlist1[_i]] = 0.0;}
 rates ( _threadargscomma_ v ) ;
 /* ~ o <-> c ( b , a )*/
 f_flux =  b * o ;
 b_flux =  a * c ;
 Do -= (f_flux - b_flux);
 Dc += (f_flux - b_flux);
 
 /*REACTION*/
   /* o + c = 1.0 */
 /*CONSERVATION*/
   } return _reset;
 }
 
/*CVODE matsol*/
 static int _ode_matsol1(void* _so, double* _rhs, double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {int _reset=0;{
 double b_flux, f_flux, _term; int _i;
   b_flux = f_flux = 0.;
 {int _i; double _dt1 = 1.0/dt;
for(_i=0;_i<2;_i++){
  	_RHS1(_i) = _dt1*(_p[_dlist1[_i]]);
	_MATELM1(_i, _i) = _dt1;
      
} }
 rates ( _threadargscomma_ v ) ;
 /* ~ o <-> c ( b , a )*/
 _term =  b ;
 _MATELM1( 1 ,1)  += _term;
 _MATELM1( 0 ,1)  -= _term;
 _term =  a ;
 _MATELM1( 1 ,0)  -= _term;
 _MATELM1( 0 ,0)  += _term;
 /*REACTION*/
   /* o + c = 1.0 */
 /*CONSERVATION*/
   } return _reset;
 }
 
/*CVODE end*/
 
static int _ode_count(int _type){ return 2;}
 
static void _ode_spec(_NrnThread* _nt, _Memb_list* _ml, int _type) {
   double* _p; Datum* _ppvar; Datum* _thread;
   Node* _nd; double _v; int _iml, _cntml;
  _cntml = _ml->_nodecount;
  _thread = _ml->_thread;
  for (_iml = 0; _iml < _cntml; ++_iml) {
    _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
    _nd = _ml->_nodelist[_iml];
    v = NODEV(_nd);
     _ode_spec1 (_p, _ppvar, _thread, _nt);
 }}
 
static void _ode_map(int _ieq, double** _pv, double** _pvdot, double* _pp, Datum* _ppd, double* _atol, int _type) { 
	double* _p; Datum* _ppvar;
 	int _i; _p = _pp; _ppvar = _ppd;
	_cvode_ieq = _ieq;
	for (_i=0; _i < 2; ++_i) {
		_pv[_i] = _pp + _slist1[_i];  _pvdot[_i] = _pp + _dlist1[_i];
		_cvode_abstol(_atollist, _atol, _i);
	}
 }
 
static void _ode_matsol_instance1(_threadargsproto_) {
 _cvode_sparse_thread(&_thread[_cvspth1]._pvoid, 2, _dlist1, _p, _ode_matsol1, _ppvar, _thread, _nt);
 }
 
static void _ode_matsol(_NrnThread* _nt, _Memb_list* _ml, int _type) {
   double* _p; Datum* _ppvar; Datum* _thread;
   Node* _nd; double _v; int _iml, _cntml;
  _cntml = _ml->_nodecount;
  _thread = _ml->_thread;
  for (_iml = 0; _iml < _cntml; ++_iml) {
    _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
    _nd = _ml->_nodelist[_iml];
    v = NODEV(_nd);
 _ode_matsol_instance1(_threadargs_);
 }}
 
static void _thread_cleanup(Datum* _thread) {
   _nrn_destroy_sparseobj_thread(_thread[_cvspth1]._pvoid);
   _nrn_destroy_sparseobj_thread(_thread[_spth1]._pvoid);
 }

static void initmodel(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {
  int _i; double _save;{
  c = c0;
  o = o0;
 {
    _ss_sparse_thread(&_thread[_spth1]._pvoid, 2, _slist1, _dlist1, _p, &t, dt, kin, _linmat1, _ppvar, _thread, _nt);
     if (secondorder) {
    int _i;
    for (_i = 0; _i < 2; ++_i) {
      _p[_slist1[_i]] += dt*_p[_dlist1[_i]];
    }}
 }
 
}
}

static void nrn_init(_NrnThread* _nt, _Memb_list* _ml, int _type){
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; double _v; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v = _v;
 initmodel(_p, _ppvar, _thread, _nt);
}
}

static double _nrn_current(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt, double _v){double _current=0.;v=_v;{ {
   i = g * o * ( v - e_gaba ) ;
   }
 _current += i;

} return _current;
}

static void nrn_cur(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; int* _ni; double _rhs, _v; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 _g = _nrn_current(_p, _ppvar, _thread, _nt, _v + .001);
 	{ _rhs = _nrn_current(_p, _ppvar, _thread, _nt, _v);
 	}
 _g = (_g - _rhs)/.001;
#if CACHEVEC
  if (use_cachevec) {
	VEC_RHS(_ni[_iml]) -= _rhs;
  }else
#endif
  {
	NODERHS(_nd) -= _rhs;
  }
 
}
 
}

static void nrn_jacob(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml];
#if CACHEVEC
  if (use_cachevec) {
	VEC_D(_ni[_iml]) += _g;
  }else
#endif
  {
     _nd = _ml->_nodelist[_iml];
	NODED(_nd) += _g;
  }
 
}
 
}

static void nrn_state(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; double _v = 0.0; int* _ni; int _iml, _cntml;
double _dtsav = dt;
if (secondorder) { dt *= 0.5; }
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
 _nd = _ml->_nodelist[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v=_v;
{
 {  sparse_thread(&_thread[_spth1]._pvoid, 2, _slist1, _dlist1, _p, &t, dt, kin, _linmat1, _ppvar, _thread, _nt);
     if (secondorder) {
    int _i;
    for (_i = 0; _i < 2; ++_i) {
      _p[_slist1[_i]] += dt*_p[_dlist1[_i]];
    }}
 }}}
 dt = _dtsav;
}

static void terminal(){}

static void _initlists(){
 double _x; double* _p = &_x;
 int _i; static int _first = 1;
  if (!_first) return;
 _slist1[0] = &(c) - _p;  _dlist1[0] = &(Dc) - _p;
 _slist1[1] = &(o) - _p;  _dlist1[1] = &(Do) - _p;
_first = 0;
}

#if defined(__cplusplus)
} /* extern "C" */
#endif

#if NMODL_TEXT
static const char* nmodl_filename = "/Users/agmccrei/Google Drive/HayLab/Microcircuit/Test_Ih_Integration/mod/tonic.mod";
static const char* nmodl_file_text = 
  ": tonic current with rectification\n"
  ": based on Pavlov et al (J Neuro 2009)\n"
  "\n"
  "NEURON{\n"
  "SUFFIX tonic\n"
  "NONSPECIFIC_CURRENT i\n"
  "RANGE i, v, a, b, g, e_gaba}\n"
  "\n"
  "PARAMETER{\n"
  "g = 0.001 (siemens/cm2)\n"
  "e_gaba = -80 (millivolt)\n"
  "}\n"
  "\n"
  "ASSIGNED{\n"
  "v (millivolt)\n"
  "i (milliampere)\n"
  "a (/ms)\n"
  "b (/ms)}\n"
  "\n"
  "STATE{o c}\n"
  "\n"
  "BREAKPOINT{\n"
  "SOLVE kin METHOD sparse\n"
  "i = g*o*(v-e_gaba)}\n"
  "\n"
  "INITIAL {SOLVE kin STEADYSTATE sparse}\n"
  "\n"
  "KINETIC kin{\n"
  "rates(v)\n"
  "~ o<->c (b, a)   : b is forward rate constant, a backward\n"
  "CONSERVE o+c=1}\n"
  "\n"
  "PROCEDURE rates(v(millivolt)) {\n"
  "LOCAL x, y\n"
  "UNITSOFF\n"
  "x = 0.1*(v+20)\n"
  "if (fabs(x)>1e-6){\n"
  "a = (50*x)/(1-exp(-x))\n"
  "} else{\n"
  "a=0.25*(v^2+(20*v)+200)\n"
  "}\n"
  "y = -0.08*(v-10)\n"
  "if(fabs(x)>1e-6){\n"
  "b = (20*y)/(1-exp(-y))\n"
  "} else{\n"
  "b = -0.064*(v^2-(45*v)+37.5)\n"
  "}\n"
  "UNITSON}\n"
  ;
#endif