TITLE Amacrine Cell Hodgkin Huxley Potassium Channel
UNITS {
(mA) = (milliamp)
(mV) = (millivolt)
}
NEURON {
SUFFIX HHk
USEION k READ ek WRITE ik
RANGE gkbar, ik
GLOBAL inf, tau
}
PARAMETER {
gkbar = 0.0002 (mho/cm2)
ek (mV)
}
STATE {
n
}
ASSIGNED {
v (mV)
celsius (degC)
ik (mA/cm2)
inf
tau (ms)
}
INITIAL {
rate(v)
n = inf
}
BREAKPOINT {
SOLVE states METHOD cnexp
ik = gkbar * n * n * n * n * (v - ek)
}
DERIVATIVE states {
rate(v)
n' = (inf - n)/tau
}
UNITSOFF
FUNCTION alp(v(mV)) {
LOCAL q10
v = -v - 65
q10 = 3
alp = 0.01 * q10 * expM1(v + 10, 10)
}
FUNCTION bet(v(mV)) {
LOCAL q10
v = -v - 65
q10 = 3^((celsius - 6.3)/10)
bet = 0.125 * q10 * exp(v/80)
}
FUNCTION expM1(x, y) {
if (fabs(x/y) < 1e-6) {
expM1 = y * (1 - x/y/2)
}
else {
expM1 = x/(exp(x/y) - 1)
}
}
PROCEDURE rate(v(mV)) {
LOCAL a, b
TABLE inf DEPEND celsius FROM -100 TO 100 WITH 200
a = alp(v)/5
b = bet(v)/5
tau = 1/(a + b)
inf = a/(a + b)
}
UNITSON