COMMENT
IinjLT.mod
Generates a train of photocurrent injections
User specifies duration of each Iinj, interpulse interval (ton and toff),
and number of pulses.
___ ___ _ _
/ \ / \ |
delay | \ toff | \ | amp
__________| \________| \_______ _|_
ton
num: 1 2 ...
ENDCOMMENT
NEURON {
POINT_PROCESS IinjLT_cone
RANGE del, ton, toff, num, amp,ssI,i
ELECTRODE_CURRENT i
}
UNITS {
(pA) = (picoamp)
(nA) = (nanoamp)
}
PARAMETER {
del = 1000 (ms)
ton = 8000 (ms) <0, 1e9> : duration of ON phase
toff = 1000 (ms) <0, 1e9> : duration of OFF phase
num = 1 : how many to deliver
amp = 20 (pA) : absolute amplitude of the light induced current
ssI = 0 (pA) : steady-state current (dark current)
}
ASSIGNED {
Ncount : counter of the number of the flashes/injections
ival (nA)
i (nA)
on
tally : how many more to deliver
tr (ms) : the relative time in each flash
Part1
Part2
Part3
Part4
ssInA (nA)
ampnA (nA)
}
INITIAL {
i = 0
ssInA=0.001*ssI
ampnA=amp*0.001
ival = 0
tally = num
Ncount=0
if (tally > 0) {
net_send(del, 1)
on = 0
tally = tally - 1
}
}
BREAKPOINT {
: printf("%g\n", t)
tr=t-del-(ton+toff)*(Ncount-1)
if (on ==1) {
Part1 = (1.01)*( 1-exp(-tr/(60/1200*ton)))^3
Part2 = -(0.07)/(1+exp(-(tr-(555/1200*ton))/(120/1200*ton)))
Part3 = -0.7/(1+exp(-(tr-(1500/1200*ton))/(200/1200*ton)))^1.3
Part4 = -(0.24)/((1+exp(-(tr-(1200/1200*ton))/(80/1200*ton))))^2
i=ssInA-ival*(Part1+Part2+Part3+Part4)
} else {
i = ssInA+ival
}
}
NET_RECEIVE (w) {
: ignore any but self-events with flag == 1
if (flag == 1) {
if (on == 0) {
: turn it on
Ncount=Ncount+1
ival = ampnA
on = 1
: prepare to turn it off
:net_send(ton, 1)
} else {
: turn it off
ival = 0
on = 0
if (tally > 0) {
: prepare to turn it on again
net_send(toff, 1)
tally = tally - 1
}
}
}
}