This is the readme file for the NEURON simulation demonstrating NMDA spikes in interneurons Instructions to run the model under Windows Xp or Win7: 1. Start mknrndll 2. Select as working directory the folder "Katona_et_al" 3. press the button "Make nrnmech.dll" 4. start Neuron 5. Select as working directory the folder "Katona_et_al" 6. type Enter 7. copy the following line to oc> command prompt: load_file("basal.hoc") 8. Please remove nmda synapses one by one from the PointProcessGroupManager window using the remove button Graph[1] demonstrates NMDA spikes in a reconstructed CA1 stratum radiatum interneuron Graph[2] shows the enlarged view of the initiation phase of the spike