//-----------------------------------------------------------------------------------------------------------//
// Localization of synaptic inputs and Ca-PIC channels over dendrites at the similar distance from the soma //
//-----------------------------------------------------------------------------------------------------------//
// global constants
v_init=-70
num_row=10000
// global variables
objref iCaL[num_row]
objref iSyn[num_row]
// localization of Ca-PIC channels and synaptic inputs at the similar Dpath
proc loc_dend(){local max_dist, err_min, i, init, end, err_dist, x_min, j
max_dist=0
err_min=0
init=0
end=0
err_dist=0
x_min=0
j=0
// calculate the longest Dpath from the soma
forall {
soma distance(0, 0)
for(x){
if (max_dist < distance(x)) {
max_dist = distance(x)
}
}
err_min=max_dist
}
// set the specific Dpath
i = 600
forall {
init = distance(0)
end = distance(1)
if (init<=i && i<end) {
for(x) {
err_dist=abs(i-distance(x))
if (err_min > err_dist) {
err_min = err_dist
x_min=x
}
}
if(x_min==0){x_min=0.0001}
if(x_min==1){x_min=0.9999}
iCaL[j] = new CaL(x_min)
iCaL[j].gcalbar=1.37 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j] = new StepSyn(x_min)
iSyn[j].ip1=0.4 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j].ip2=-0.3 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j].ip3=0.2 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j].ip4=0.3 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j].ip5=-0.41 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j].i0=0.25 * area(x_min) * (10^-4)^2 * 10^3 //600um [mS/cm2]
iSyn[j].s=1
j=j+1
err_min=max_dist
}
}
}
loc_dend()