TITLE Modified Hill-Mashima muscle model
UNITS {}
NEURON {
SUFFIX fHill
RANGE a0, b0, c0, d0
RANGE p0, g1, g2, g3
RANGE Kse, A, Fc, F
RANGE xm_init, xm, xce_init, xce
USEION mg READ mgi VALENCE 2
USEION cl READ cli
}
PARAMETER {
a0 = 2.35 :[N]
b0 = 24.35 :[mm*s-1]
c0 = -7.4 :[N]
d0 = 30.3 :[mm*s-1]
p0 = 23 :[N]
g1 = -8 :[mm]
g2 = 21.4 :[mm]
xm_init = -8 :[mm]
xce_init = -8 :[mm]
Kse = 0.4 :[mm-1]
}
STATE {
A
xce
xm
}
ASSIGNED {
F
Fc
mgi
cli
}
BREAKPOINT { LOCAL d_xm, d_xce, d_se
A = mgi
xm = cli
SOLVE state_hill METHOD cnexp
F = p0*Kse*xse(xm, xce)
}
DERIVATIVE state_hill {
Fc = p0*g(xm)*A
xce' = dxdt (F, Fc)
}
FUNCTION xse (x, y) { LOCAL d_xm, d_xce, d_se
d_xm = xm - xm_init
d_xce = xce - xce_init
d_se = d_xm - d_xce
if (d_se <= 0) {xse = 0}
else {xse = d_se}
}
FUNCTION g (x) {
g = exp(-((x-g1)/g2)^2)
}
FUNCTION dxdt (x, xc) {LOCAL gain_length
if (x <= xc) {
dxdt = (10^-3)*(-b0*(xc-x))/(x+a0*xc/p0)
} else {
gain_length = (-d0*(xc-x))/(2*xc-x+c0*xc/p0)
if (gain_length <= 0) {dxdt = (10^-3)*1e5}
else {dxdt = (10^-3)*gain_length}
}
}
INITIAL {
A = 0
xm = xm_init
xce = xce_init
F=1e-5
}