<StimulationSet> <!-- the injectionSite must match a regionLabel deefined in the morphology --> <!-- one dendrite injection, specifying sa2[0:3], with a rate distributed over all the spine (each spine gets total/num spines) DHGP has been changed to once per Ca pulse, but 1/4 the value--> <!-- *****************TRAIN 1 *** DHPG inject **********--> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 20000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 20066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!-- Ca pulses TRAIN 1 -- 40 Ca pulses --> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 20000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 20066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 20000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 20066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********DHPG *******TRAIN 2************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 35000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 35066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!-- Ca pulses TRAIN 2 - 80 total Ca pulses --> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 35000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 35066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 35000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 35066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*********DHPG******TRAIN 3***************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 50000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 50066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!-----Calcium TRAIN 3-----120 total Ca pulses ------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 50000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 50066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 50000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 50066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********DHPG******TRAIN 4******************------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 65000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 65066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!---***Ca TRAIN 4 - 160 total pulses --------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 65000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 65066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 65000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 65066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*********DHPG******TRAIN 5***************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 80000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 80066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*******Ca TRAIN 5 200 pulses **********------------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 80000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 80066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 80000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 80066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********DHPG******TRAIN 6******************------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 95000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 95066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********Calcium******TRAIN 6******* 240 total Ca pulses ***********------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 95000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 95066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 95000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 95066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*********DHPG******TRAIN 7***************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 110000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 110066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********Calcium******TRAIN 7******* 280 total Ca pulses ***********------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 110000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 110066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 110000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 110066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*********DHPG******TRAIN 8***************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 125000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 125066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********Calcium******TRAIN 8******* 320 total Ca pulses ***********------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 125000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 125066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 125000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 125066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*********DHPG******TRAIN 9***************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 140000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 140066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********Calcium******TRAIN 9******* 360 total Ca pulses ***********------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 140000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 140066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 140000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 140066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------*********DHPG******TRAIN 10***************----------> <InjectionStim specieID="Dhpg" injectionSite="sa1[0,7].pointA"> <onset> 155000 </onset> <duration> 5 </duration> <rate> 60.0 </rate> <period> 20 </period> <end> 155066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <!--------**********Calcium******TRAIN 10******* 320 total Ca pulses ***********------> <InjectionStim specieID="Ca" injectionSite="sa1[0,7].pointA"> <onset> 155000 </onset> <duration> 3 </duration> <rate> 1024 </rate> <period> 20 </period> <end> 155066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> <InjectionStim specieID="Ca" injectionSite="sa2[0:30].pointD"> <onset> 155000 </onset> <duration> 3 </duration> <rate> 260 </rate> <period> 20 </period> <end> 155066 </end> <numTrains> 10 </numTrains> <interTrainInterval> 29 </interTrainInterval> </InjectionStim> </StimulationSet>