:Comment : The transient component of the K current
:Reference : : Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats:subtypes and gradients,Korngreen and Sakmann, J. Physiology, 2000
:Comment : shifted -10 mv to correct for junction potential
:Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21
: **Modified to use 'celsius' for temperature to correct rates by Aman Aberra**
NEURON {
SUFFIX K_Tst
USEION k READ ek WRITE ik
RANGE gK_Tstbar, gK_Tst, ik
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gK_Tstbar = 0.00001 (S/cm2)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
gK_Tst (S/cm2)
mInf
mTau
hInf
hTau
}
STATE {
m
h
}
BREAKPOINT {
SOLVE states METHOD cnexp
gK_Tst = gK_Tstbar*(m^4)*h
ik = gK_Tst*(v-ek)
}
DERIVATIVE states {
rates()
m' = (mInf-m)/mTau
h' = (hInf-h)/hTau
}
INITIAL{
rates()
m = mInf
h = hInf
}
PROCEDURE rates(){
LOCAL qt
:qt = 2.3^((34-21)/10)
qt = 2.3^((celsius-21)/10)
UNITSOFF
v = v + 10
mInf = 1/(1 + exp(-(v+0)/19))
mTau = (0.34+0.92*exp(-((v+71)/59)^2))/qt
hInf = 1/(1 + exp(-(v+66)/-10))
hTau = (8+49*exp(-((v+73)/23)^2))/qt
v = v - 10
UNITSON
}