Folders ======= Attenuation ^^^^^^^^^^^ For investigating the attenuation of the cell. Utilizes a -0.05 mA current clamp. .. image:: ../../L5NeuronSimulation/Attenuation/Attenuation.svg :alt: Attenuation Plot F-ICurve ^^^^^^^^ Creates the F-I curve for the cell. The reference current is 1.2 mA. .. image:: ../../L5NeuronSimulation/F-ICurve/F-ICurve.svg :alt: F-I Curve Resistance ^^^^^^^^^^ Looking at the cell's input resistance. biophys_components ^^^^^^^^^^^^^^^^^^ This is where mechanisms and templates are stored. This folder is used as the basis for all simulations in the project. * mechanisms: where mod files are. pyr2pyr.mod and int2pyr.mod are the synapse mechanisms used. * morphologies: morphology files. cell1.asc is used. * synaptic_models: JSON files containing synaptic parameters. PN2PN.json and INT2PN.json are used. * templates: hoc cell templates. L5PCtemplate.hoc is the main template, and it utilizes L5PCbiophys3.hoc. EPSP_Tuning ^^^^^^^^^^^ .. warning:: THIS NEEDS WORK Group_EPSC_Tuning ^^^^^^^^^^^^^^^^^ Where EPSC tuning is performed (on both basal and apical dendrites). .. warning:: THIS NEEDS WORK HayFiringProperties ^^^^^^^^^^^^^^^^^^^ Confirming that our cell model matches the experimental firing properties that Hay et al. 2011 tuned for. .. image:: images/HayFigure.png :alt: Hay Figure IPSC_Tuning ^^^^^^^^^^^ Where IPSC tuning is performed (perisomatic, basal, and apical). .. warning:: THIS NEEDS WORK MorphAnalysis ^^^^^^^^^^^^^ Folder for exploring the morphology of the cell. Plot_Cell ^^^^^^^^^ Folder for plotting the cell and synapse locations on the cell. ShortPlasticity ^^^^^^^^^^^^^^^ Used to build and check short term plasticity for both excitation and inhibition. StepCurrent ^^^^^^^^^^^ Used to ensure that a suprathreshold step current (0.793 mA) induces the proper behavior (as determined by Hay et al. 2011). .. image:: ../../L5NeuronSimulation/StepCurrent/StepCurrent.svg :alt: Step Current Plot