from getCells import NeymotinCell
cell = NeymotinCell()
cfg = {'ihGbar' : 1.0, # multiplicative factor for ih gbar in PT cells\
'ihGbarBasal' : 1.0, # 0.1 # multiplicative factor for ih gbar in PT cells
'ihlkc' : 0.2, # ih leak param (used in Migliore)
'ihlkcBasal' : 1.0,
'ihlkcBelowSoma' : 0.01,
'ihlke' : -86, # ih leak param (used in Migliore)
'ihSlope' : 14*2,
'somaNa' : 5,
'dendNa' : 0.3,
'axonNa' : 7,
'axonRa' : 0.005,
'gpas' : 0.5, # multiplicative factor for pas g in PT cells
'epas' : 0.9} # multiplicative factor for pas e in PT cells
from neuron import h
for sec in h.allsec():
for seg in sec.allseg():
if 'hd' in dir(seg):
seg.hd.gbar = seg.hd.gbar * cfg['ihGbar']
seg.hd.clk = cfg['ihlkc']
seg.hd.elk = cfg['ihlkc']
print('changed Ih in ' + str(seg))
for sec in cell.dend:
for seg in sec.allseg():
if 'hd' in dir(seg):
seg.hd.gbar = seg.hd.gbar * cfg['ihGbarBasal']
seg.hd.clk = seg.hd.clk * cfg['ihlkcBelowSoma']
print('changed Ih in ' + str(seg))
for seg in cell.soma.allseg():
if 'hd' in dir(seg):
seg.hd.clk = seg.hd.clk * cfg['ihlkcBelowSoma']
print('changed Ih in ' + str(seg))
for sec in cell.dend:
for seg in sec.allseg():
if 'nax' in dir(seg):
seg.nax.gbar = 0.0153130368342 * cfg['dendNa']
if 'pas' in dir(seg):
seg.pas.e = seg.pas.e * cfg['epas']
seg.pas.g = seg.pas.g * cfg['gpas']
for sec in cell.apic:
for seg in sec.allseg():
if 'nax' in dir(seg):
seg.nax.gbar = 0.0153130368342 * cfg['dendNa']
if 'pas' in dir(seg):
seg.pas.e = seg.pas.e * cfg['epas']
seg.pas.g = seg.pas.g * cfg['gpas']
for seg in cell.soma.allseg():
if 'nax' in dir(seg):
seg.nax.gbar = 0.0153130368342 * cfg['somaNa']
for seg in cell.axon.allseg():
if 'nax' in dir(seg):
seg.nax.gbar = 0.0153130368342 * cfg['axonNa']
if 'geom' in dir(seg):
seg.geom.Ra = 137.494564931 * cfg['axonRa'] #0.005
# from chirpUtils import applyChirp, getChirp
# amp = 0.001
# f0, f1, t0, Fs, delay = 0.5, 50, 50, 1000, 12 # for looking at bimodal leading phase response in Hay cell
# I, t = getChirp(f0, f1, t0, amp, Fs, delay)
# seg = cell.apic[26](0.5)
# print('running chirp on ' + str(seg))
# out = applyChirp(I, t, seg, cell.soma(0.5), t0, delay, Fs, f1, out_file_name='/u/craig/L5PYR_Resonance/Neymotin/testPTadjust')