// genesis - inputs2.g - Modified functions used in the Popup menu
// This file was developed by
// Akira Takashima.
// Department of Biological Sciences
// Faculry of Science
// Hokkaido University
// Sapporo Japan
//
// Last update on 22 Jan. 2007
//=======================================================================
// makeinputs - the main function to set up injection and synaptic inputs
//=======================================================================
function makeinputs
// Default values of parameters - (global variables defined in Cable.g)
float syndelay = 0 // msec
float synwidth = 1000 //1000// choose width and interval to give a single spike
float syninterval = 100000
create neutral /input
//==================================================
// spike for synaptic input - only a single spike
//==================================================
// pulse to gate spike train
create pulsegen /input/synpulse
create spikegen /input/synpulse/spike
setspikes {syndelay} {synwidth} {syninterval}
// setfield /input/synpulse width1 0.001 delay1 0.02 baselevel 0.0 \
// level1 1.0 trig_mode 0 width2 0.0 delay2 1 output 1
setfield /input/synpulse/spike abs_refract 0.01 output_amp 1 thresh 0.5
addmsg /input/synpulse /input/synpulse/spike INPUT output
// Lastly, make connection to chemically activated dendrite channel
// using a SPIKE message
// set_chan_params {gsyn} {tsyn} {Vsyn}
// initially, make both injection and synaptic input to the soma
end// makeinputs
//=======================================================
// functions used in the change synaptic input menu
//=======================================================
function syn_toggle// toggles synaptic input ON/OFF
if ({getfield /output/synapse_menu/syntoggle state} == 1)
// ON
setfield /input/synpulse level1 1.0
echo "Synaptic Input ON!"
else
// OFF
setfield /input/synpulse level1 0.0
echo " Synaptic Input OFF!"
end
end
function set_chan_params( comp_no, gsyn, tsyn, Vsyn )
int comp_no = ({getfield /output/synapse_menu/comp_no value})
str gsyn, tsyn, Vsyn
/* if ({exists /cell/solve})
delete /cell/solve
end
*/
if ((comp_no) <= 0)
setfield /cell/soma/Ex_chan Ek {Vsyn}
setfield /cell/soma/Ex_chan tau1 {tsyn} tau2 {tsyn}
setfield /cell/soma/Ex_chan gmax {gsyn}
echo "Soma Ex_chan has changed!"
else
setfield /cell/dend[{comp_no}]/Ex_chan Ek {Vsyn}
setfield /cell/dend[{comp_no}]/Ex_chan tau1 {tsyn} tau2 {tsyn}
setfield /cell/dend[{comp_no}]/Ex_chan gmax {gsyn}
echo "dend["{comp_no}"] Ex_chan has changed!"
end
end
// links channel which computes channel current (channelC2) with compartment
function link_channel2(channel, compartment)
addmsg {channel} {compartment} CHANNEL Gk Ek
addmsg {compartment} {channel} VOLTAGE Vm
end
function add_syn_input
// compartment # for input - #0 = Soma
int comp_no
int NCableSects = 492
comp_no = ({getfield /output/synapse_menu/comp_no value})
if ((comp_no) > ({NCableSects}))
echo "There are only "{NCableSects}" cable compartments!"
return
end
/* if ({exists /cell/solve})
delete /cell/solve
end
*/
if ((comp_no) <= 0) // then input to soma
addmsg /input/synpulse/spike /cell/soma/Ex_chan SPIKE
setfield /cell/soma/Ex_chan synapse[0].weight 1 synapse[0].delay 0
// link_channel2 /cell/soma/Ex_chan /cell/soma
echo "Synaptic input is to the soma"
else
addmsg /input/synpulse/spike /cell/dend[{comp_no}]/Ex_chan SPIKE
setfield /cell/dend[{comp_no}]/Ex_chan synapse[0].weight 1 synapse[0].delay 0
// link_channel2 /cell/dend[{comp_no}]/Ex_chan /cell/dend[{comp_no }]
echo "Synaptic input is to dendrite compartment number " {getfield /output/synapse_menu/comp_no value}
end
end
function set_inputs// set parameters for synaptic input from dialog boxes
float syndelay = 0 // msec
float synwidth = 1000// choose width and interval to give a single spike
float syninterval = 100000
int comp_no
comp_no = ({getfield /output/synapse_menu/comp_no value})
str dialog = "/output/synapse_menu"
set_chan_params {comp_no} {getfield {dialog}/gsyn value} \
{getfield {dialog}/tsyn value} {getfield {dialog}/vsyn value}
// after so many changes, we need to reset everything
reset
echo "Maximum conductance = "{getfield {dialog}/gsyn value}
echo "Time constant for conductance = "{getfield {dialog}/tsyn value}
echo "Channel equilibrium potential = "{getfield {dialog}/vsyn value}
end
function remove_synaptic_input
int i, n, nmsg
int NCableSects
NCableSects = 492
/* if ({exists /cell/solve})
delete /cell/solve
end
*/
for (i = 0; i < {NCableSects}; i = i + 1)
if ( i <= 0 )
nmsg = {getmsg /cell/soma/Ex_chan -incoming -count}
for (n = 0; n < nmsg; n = n + 1)
if ({getmsg /cell/soma/Ex_chan -in -type {n}} == "SPIKE" )
echo deleting message {n}
deletemsg /cell/soma/Ex_chan {n} -incoming
break
end
end
else
nmsg = {getmsg /cell/dend[{i}]/Ex_chan -incoming -count}
for (n = 0; n < nmsg; n = n + 1)
if ({getmsg /cell/dend[{i}]/Ex_chan -in -type {n}} == "SPIKE")
echo deleting message {n}
deletemsg /cell/dend[{i}]/Ex_chan {n} -incoming
break
end // if
end // for n
end
end // for i
if ({exists /LDS/draw/xcell2})
delete /LDS/draw/xcell2
else
echo "/LDS/draw/xcell2 doesn't exist!"
end
if ({exists /LDS/draw/xcell3})
delete /LDS/draw/xcell3
delete /LDS/draw/xcell4
delete /LDS/draw/xcell5
delete /LDS/draw/xcell6
delete /LDS/draw/xcell7
else
echo "/LDS/draw/xcell3 doesn't exist!"
end
if ({exists /LDS/draw/xcell8})
delete /LDS/draw/xcell8
delete /LDS/draw/xcell9
delete /LDS/draw/xcell10
delete /LDS/draw/xcell11
delete /LDS/draw/xcell12
else
echo "/LDS/draw/xcell8 doesn't exist!"
end
if ({exists /LDS/draw/xcell13})
delete /LDS/draw/xcell13
delete /LDS/draw/xcell14
delete /LDS/draw/xcell15
delete /LDS/draw/xcell16
delete /LDS/draw/xcell17
delete /LDS/draw/xcell18
delete /LDS/draw/xcell19
delete /LDS/draw/xcell20
delete /LDS/draw/xcell21
delete /LDS/draw/xcell22
delete /LDS/draw/xcell23
else
echo "/LDS/draw/xcell13 dosen't exist!"
end
if ({exists /LDS/draw/xcell33})
delete /LDS/draw/xcell33
delete /LDS/draw/xcell34
delete /LDS/draw/xcell35
delete /LDS/draw/xcell36
delete /LDS/draw/xcell37
delete /LDS/draw/xcell38
delete /LDS/draw/xcell39
delete /LDS/draw/xcell40
delete /LDS/draw/xcell41
delete /LDS/draw/xcell42
delete /LDS/draw/xcell43
delete /LDS/draw/xcell44
delete /LDS/draw/xcell45
delete /LDS/draw/xcell46
delete /LDS/draw/xcell47
delete /LDS/draw/xcell48
delete /LDS/draw/xcell49
delete /LDS/draw/xcell50
delete /LDS/draw/xcell51
delete /LDS/draw/xcell52
else
echo "/LDS/draw/xcell33 dosen't exist!"
end
echo "Removing all synaptic inputs!"
end
//=======================================================
// functions used in the change synaptic input menu
//=======================================================
function setspikes(delay, width, interval)
str pulser = "/input/synpulse"
str spiker = "/input/synpulse/spike"
float delay, width, interval, width2
setfield {pulser} width1 {width} delay1 {delay} baselevel 0.0 \
trig_mode 0 delay2 100000
// free run mode with very long delay for 2nd pulse (non-repetitive)
// level1 is set by the syn_toggle function
setfield {spiker} abs_refract {interval} output_amp 1 thresh 0.5
end
function set_input_timing
str dialog = "/output/synapse_menu"
// setinjection {getfield {dialog}/delay value} \
// {getfield {dialog}/width value}
setspikes {getfield {dialog}/delay value} \
{getfield {dialog}/width value} \
{getfield {dialog}/interval value}
// set spike amplitudes to 1.0/dt
echo "Synaptic input delay = "{getfield {dialog}/delay value}
echo "Synaptic input width = "{getfield {dialog}/width value}
echo "Synaptic input interval = "{getfield {dialog}/interval value}
end
//EOF