\contentsline {section}{\numberline {1}Introduction}{4} \contentsline {section}{\numberline {2}Structure of compartmental models}{5} \contentsline {section}{\numberline {3}Distributed and point input to a segment}{6} \contentsline {subsection}{\numberline {3.1}Axial current in the absence of distributed and point current input}{6} \contentsline {subsection}{\numberline {3.2}Motivation for partitioning point current input - model accuracy}{7} \contentsline {subsection}{\numberline {3.3}Partitioning rule for transmembrane current}{8} \contentsline {subsection}{\numberline {3.4}Specification of transmembrane current}{9} \contentsline {section}{\numberline {4}Representation of partitioned transmembrane current}{9} \contentsline {subsection}{\numberline {4.1}Point sources of transmembrane current}{10} \contentsline {subsection}{\numberline {4.2}Generalisation of partitioning rule for point input}{10} \contentsline {subsection}{\numberline {4.3}Special and general solutions of the point input partitioning equations}{13} \contentsline {subsubsection}{\numberline {4.3.1}Single synaptic input}{13} \contentsline {subsubsection}{\numberline {4.3.2}Multiple point inputs}{13} \contentsline {subsubsection}{\numberline {4.3.3}Exogenous input}{14} \contentsline {subsection}{\numberline {4.4}Distributed transmembrane current}{14} \contentsline {subsubsection}{\numberline {4.4.1}Capacitative transmembrane current}{15} \contentsline {subsubsection}{\numberline {4.4.2}Intrinsic voltage-dependent transmembrane current}{16} \contentsline {section}{\numberline {5}Construction of the model differential equations}{16} \contentsline {subsection}{\numberline {5.1}Some additional comments}{18} \contentsline {section}{\numberline {6}The model neuron}{19} \contentsline {subsection}{\numberline {6.1}Analytical solution}{20} \contentsline {section}{\numberline {7}Simulation exercises}{20} \contentsline {subsection}{\numberline {7.1}First simulation exercise}{21} \contentsline {subsubsection}{\numberline {7.1.1}Results}{21} \contentsline {subsection}{\numberline {7.2}Second simulation exercise}{24} \contentsline {section}{\numberline {8}Concluding remarks}{25} \vskip 8pt \bf \hskip 18pt References\hfill 26 \vskip 4pt