/* Created by Language version: 7.7.0 */
/* VECTORIZED */
#define NRN_VECTORIZED 1
#include <stdio.h>
#include <stdlib.h>
#include <math.h>
#include "scoplib_ansi.h"
#undef PI
#define nil 0
#include "md1redef.h"
#include "section.h"
#include "nrniv_mf.h"
#include "md2redef.h"
 
#if METHOD3
extern int _method3;
#endif

#if !NRNGPU
#undef exp
#define exp hoc_Exp
extern double hoc_Exp(double);
#endif
 
#define nrn_init _nrn_init__ih
#define _nrn_initial _nrn_initial__ih
#define nrn_cur _nrn_cur__ih
#define _nrn_current _nrn_current__ih
#define nrn_jacob _nrn_jacob__ih
#define nrn_state _nrn_state__ih
#define _net_receive _net_receive__ih 
#define state state__ih 
 
#define _threadargscomma_ _p, _ppvar, _thread, _nt,
#define _threadargsprotocomma_ double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt,
#define _threadargs_ _p, _ppvar, _thread, _nt
#define _threadargsproto_ double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt
 	/*SUPPRESS 761*/
	/*SUPPRESS 762*/
	/*SUPPRESS 763*/
	/*SUPPRESS 765*/
	 extern double *getarg();
 /* Thread safe. No static _p or _ppvar. */
 
#define t _nt->_t
#define dt _nt->_dt
#define gbar _p[0]
#define ascale _p[1]
#define bscale _p[2]
#define ashift _p[3]
#define aslope _p[4]
#define bslope _p[5]
#define i _p[6]
#define m _p[7]
#define Dm _p[8]
#define v _p[9]
#define _g _p[10]
 
#if MAC
#if !defined(v)
#define v _mlhv
#endif
#if !defined(h)
#define h _mlhh
#endif
#endif
 
#if defined(__cplusplus)
extern "C" {
#endif
 static int hoc_nrnpointerindex =  -1;
 static Datum* _extcall_thread;
 static Prop* _extcall_prop;
 /* external NEURON variables */
 /* declaration of user functions */
 static void _hoc_alpha(void);
 static void _hoc_beta(void);
 static int _mechtype;
extern void _nrn_cacheloop_reg(int, int);
extern void hoc_register_prop_size(int, int, int);
extern void hoc_register_limits(int, HocParmLimits*);
extern void hoc_register_units(int, HocParmUnits*);
extern void nrn_promote(Prop*, int, int);
extern Memb_func* memb_func;
 
#define NMODL_TEXT 1
#if NMODL_TEXT
static const char* nmodl_file_text;
static const char* nmodl_filename;
extern void hoc_reg_nmodl_text(int, const char*);
extern void hoc_reg_nmodl_filename(int, const char*);
#endif

 extern void _nrn_setdata_reg(int, void(*)(Prop*));
 static void _setdata(Prop* _prop) {
 _extcall_prop = _prop;
 }
 static void _hoc_setdata() {
 Prop *_prop, *hoc_getdata_range(int);
 _prop = hoc_getdata_range(_mechtype);
   _setdata(_prop);
 hoc_retpushx(1.);
}
 /* connect user functions to hoc names */
 static VoidFunc hoc_intfunc[] = {
 "setdata_ih", _hoc_setdata,
 "alpha_ih", _hoc_alpha,
 "beta_ih", _hoc_beta,
 0, 0
};
#define alpha alpha_ih
#define beta beta_ih
 extern double alpha( _threadargsprotocomma_ double );
 extern double beta( _threadargsprotocomma_ double );
 /* declare global and static user variables */
#define erev erev_ih
 double erev = -45;
#define q10 q10_ih
 double q10 = 2.2;
 /* some parameters have upper and lower limits */
 static HocParmLimits _hoc_parm_limits[] = {
 0,0,0
};
 static HocParmUnits _hoc_parm_units[] = {
 "erev_ih", "mV",
 "gbar_ih", "S/cm2",
 "i_ih", "mA/cm2",
 0,0
};
 static double delta_t = 0.01;
 static double m0 = 0;
 /* connect global user variables to hoc */
 static DoubScal hoc_scdoub[] = {
 "erev_ih", &erev_ih,
 "q10_ih", &q10_ih,
 0,0
};
 static DoubVec hoc_vdoub[] = {
 0,0,0
};
 static double _sav_indep;
 static void nrn_alloc(Prop*);
static void  nrn_init(_NrnThread*, _Memb_list*, int);
static void nrn_state(_NrnThread*, _Memb_list*, int);
 static void nrn_cur(_NrnThread*, _Memb_list*, int);
static void  nrn_jacob(_NrnThread*, _Memb_list*, int);
 
static int _ode_count(int);
static void _ode_map(int, double**, double**, double*, Datum*, double*, int);
static void _ode_spec(_NrnThread*, _Memb_list*, int);
static void _ode_matsol(_NrnThread*, _Memb_list*, int);
 
#define _cvode_ieq _ppvar[0]._i
 static void _ode_matsol_instance1(_threadargsproto_);
 /* connect range variables in _p that hoc is supposed to know about */
 static const char *_mechanism[] = {
 "7.7.0",
"ih",
 "gbar_ih",
 "ascale_ih",
 "bscale_ih",
 "ashift_ih",
 "aslope_ih",
 "bslope_ih",
 0,
 "i_ih",
 0,
 "m_ih",
 0,
 0};
 
extern Prop* need_memb(Symbol*);

static void nrn_alloc(Prop* _prop) {
	Prop *prop_ion;
	double *_p; Datum *_ppvar;
 	_p = nrn_prop_data_alloc(_mechtype, 11, _prop);
 	/*initialize range parameters*/
 	gbar = 0.00015;
 	ascale = 0.00643;
 	bscale = 0.193;
 	ashift = 154.9;
 	aslope = 11.9;
 	bslope = 33.1;
 	_prop->param = _p;
 	_prop->param_size = 11;
 	_ppvar = nrn_prop_datum_alloc(_mechtype, 1, _prop);
 	_prop->dparam = _ppvar;
 	/*connect ionic variables to this model*/
 
}
 static void _initlists();
  /* some states have an absolute tolerance */
 static Symbol** _atollist;
 static HocStateTolerance _hoc_state_tol[] = {
 0,0
};
 extern Symbol* hoc_lookup(const char*);
extern void _nrn_thread_reg(int, int, void(*)(Datum*));
extern void _nrn_thread_table_reg(int, void(*)(double*, Datum*, Datum*, _NrnThread*, int));
extern void hoc_register_tolerance(int, HocStateTolerance*, Symbol***);
extern void _cvode_abstol( Symbol**, double*, int);

 void _h_kole_reg() {
	int _vectorized = 1;
  _initlists();
 	register_mech(_mechanism, nrn_alloc,nrn_cur, nrn_jacob, nrn_state, nrn_init, hoc_nrnpointerindex, 1);
 _mechtype = nrn_get_mechtype(_mechanism[1]);
     _nrn_setdata_reg(_mechtype, _setdata);
 #if NMODL_TEXT
  hoc_reg_nmodl_text(_mechtype, nmodl_file_text);
  hoc_reg_nmodl_filename(_mechtype, nmodl_filename);
#endif
  hoc_register_prop_size(_mechtype, 11, 1);
  hoc_register_dparam_semantics(_mechtype, 0, "cvodeieq");
 	hoc_register_cvode(_mechtype, _ode_count, _ode_map, _ode_spec, _ode_matsol);
 	hoc_register_tolerance(_mechtype, _hoc_state_tol, &_atollist);
 	hoc_register_var(hoc_scdoub, hoc_vdoub, hoc_intfunc);
 	ivoc_help("help ?1 ih /Users/salvadord/Documents/ISB/Models/M1_NetPyNE_CellReports_2023/sim/mod/h_kole.mod\n");
 hoc_register_limits(_mechtype, _hoc_parm_limits);
 hoc_register_units(_mechtype, _hoc_parm_units);
 }
static int _reset;
static char *modelname = "Ih-current";

static int error;
static int _ninits = 0;
static int _match_recurse=1;
static void _modl_cleanup(){ _match_recurse=1;}
 
static int _ode_spec1(_threadargsproto_);
/*static int _ode_matsol1(_threadargsproto_);*/
 static int _slist1[1], _dlist1[1];
 static int state(_threadargsproto_);
 
double alpha ( _threadargsprotocomma_ double _lv ) {
   double _lalpha;
 _lalpha = ascale * ( _lv + ashift ) / ( exp ( ( _lv + ashift ) / aslope ) - 1.0 ) ;
   
return _lalpha;
 }
 
static void _hoc_alpha(void) {
  double _r;
   double* _p; Datum* _ppvar; Datum* _thread; _NrnThread* _nt;
   if (_extcall_prop) {_p = _extcall_prop->param; _ppvar = _extcall_prop->dparam;}else{ _p = (double*)0; _ppvar = (Datum*)0; }
  _thread = _extcall_thread;
  _nt = nrn_threads;
 _r =  alpha ( _p, _ppvar, _thread, _nt, *getarg(1) );
 hoc_retpushx(_r);
}
 
double beta ( _threadargsprotocomma_ double _lv ) {
   double _lbeta;
 _lbeta = bscale * exp ( _lv / bslope ) ;
   
return _lbeta;
 }
 
static void _hoc_beta(void) {
  double _r;
   double* _p; Datum* _ppvar; Datum* _thread; _NrnThread* _nt;
   if (_extcall_prop) {_p = _extcall_prop->param; _ppvar = _extcall_prop->dparam;}else{ _p = (double*)0; _ppvar = (Datum*)0; }
  _thread = _extcall_thread;
  _nt = nrn_threads;
 _r =  beta ( _p, _ppvar, _thread, _nt, *getarg(1) );
 hoc_retpushx(_r);
}
 
/*CVODE*/
 static int _ode_spec1 (double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {int _reset = 0; {
   Dm = ( 1.0 - m ) * alpha ( _threadargscomma_ v ) - m * beta ( _threadargscomma_ v ) ;
   }
 return _reset;
}
 static int _ode_matsol1 (double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {
 Dm = Dm  / (1. - dt*( ( ( ( - 1.0 ) ) )*( alpha ( _threadargscomma_ v ) ) - ( 1.0 )*( beta ( _threadargscomma_ v ) ) )) ;
  return 0;
}
 /*END CVODE*/
 static int state (double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) { {
    m = m + (1. - exp(dt*(( ( ( - 1.0 ) ) )*( alpha ( _threadargscomma_ v ) ) - ( 1.0 )*( beta ( _threadargscomma_ v ) ))))*(- ( ( ( 1.0 ) )*( alpha ( _threadargscomma_ v ) ) ) / ( ( ( ( - 1.0 ) ) )*( alpha ( _threadargscomma_ v ) ) - ( 1.0 )*( beta ( _threadargscomma_ v ) ) ) - m) ;
   }
  return 0;
}
 
static int _ode_count(int _type){ return 1;}
 
static void _ode_spec(_NrnThread* _nt, _Memb_list* _ml, int _type) {
   double* _p; Datum* _ppvar; Datum* _thread;
   Node* _nd; double _v; int _iml, _cntml;
  _cntml = _ml->_nodecount;
  _thread = _ml->_thread;
  for (_iml = 0; _iml < _cntml; ++_iml) {
    _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
    _nd = _ml->_nodelist[_iml];
    v = NODEV(_nd);
     _ode_spec1 (_p, _ppvar, _thread, _nt);
 }}
 
static void _ode_map(int _ieq, double** _pv, double** _pvdot, double* _pp, Datum* _ppd, double* _atol, int _type) { 
	double* _p; Datum* _ppvar;
 	int _i; _p = _pp; _ppvar = _ppd;
	_cvode_ieq = _ieq;
	for (_i=0; _i < 1; ++_i) {
		_pv[_i] = _pp + _slist1[_i];  _pvdot[_i] = _pp + _dlist1[_i];
		_cvode_abstol(_atollist, _atol, _i);
	}
 }
 
static void _ode_matsol_instance1(_threadargsproto_) {
 _ode_matsol1 (_p, _ppvar, _thread, _nt);
 }
 
static void _ode_matsol(_NrnThread* _nt, _Memb_list* _ml, int _type) {
   double* _p; Datum* _ppvar; Datum* _thread;
   Node* _nd; double _v; int _iml, _cntml;
  _cntml = _ml->_nodecount;
  _thread = _ml->_thread;
  for (_iml = 0; _iml < _cntml; ++_iml) {
    _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
    _nd = _ml->_nodelist[_iml];
    v = NODEV(_nd);
 _ode_matsol_instance1(_threadargs_);
 }}

static void initmodel(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt) {
  int _i; double _save;{
  m = m0;
 {
   double _la , _lb ;
 _la = alpha ( _threadargscomma_ v ) ;
   _lb = beta ( _threadargscomma_ v ) ;
   m = _la / ( _la + _lb ) ;
   }
 
}
}

static void nrn_init(_NrnThread* _nt, _Memb_list* _ml, int _type){
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; double _v; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v = _v;
 initmodel(_p, _ppvar, _thread, _nt);
}
}

static double _nrn_current(double* _p, Datum* _ppvar, Datum* _thread, _NrnThread* _nt, double _v){double _current=0.;v=_v;{ {
   i = gbar * m * ( v - erev ) ;
   }
 _current += i;

} return _current;
}

static void nrn_cur(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; int* _ni; double _rhs, _v; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 _g = _nrn_current(_p, _ppvar, _thread, _nt, _v + .001);
 	{ _rhs = _nrn_current(_p, _ppvar, _thread, _nt, _v);
 	}
 _g = (_g - _rhs)/.001;
#if CACHEVEC
  if (use_cachevec) {
	VEC_RHS(_ni[_iml]) -= _rhs;
  }else
#endif
  {
	NODERHS(_nd) -= _rhs;
  }
 
}
 
}

static void nrn_jacob(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml];
#if CACHEVEC
  if (use_cachevec) {
	VEC_D(_ni[_iml]) += _g;
  }else
#endif
  {
     _nd = _ml->_nodelist[_iml];
	NODED(_nd) += _g;
  }
 
}
 
}

static void nrn_state(_NrnThread* _nt, _Memb_list* _ml, int _type) {
double* _p; Datum* _ppvar; Datum* _thread;
Node *_nd; double _v = 0.0; int* _ni; int _iml, _cntml;
#if CACHEVEC
    _ni = _ml->_nodeindices;
#endif
_cntml = _ml->_nodecount;
_thread = _ml->_thread;
for (_iml = 0; _iml < _cntml; ++_iml) {
 _p = _ml->_data[_iml]; _ppvar = _ml->_pdata[_iml];
 _nd = _ml->_nodelist[_iml];
#if CACHEVEC
  if (use_cachevec) {
    _v = VEC_V(_ni[_iml]);
  }else
#endif
  {
    _nd = _ml->_nodelist[_iml];
    _v = NODEV(_nd);
  }
 v=_v;
{
 {   state(_p, _ppvar, _thread, _nt);
  }}}

}

static void terminal(){}

static void _initlists(){
 double _x; double* _p = &_x;
 int _i; static int _first = 1;
  if (!_first) return;
 _slist1[0] = &(m) - _p;  _dlist1[0] = &(Dm) - _p;
_first = 0;
}

#if defined(__cplusplus)
} /* extern "C" */
#endif

#if NMODL_TEXT
static const char* nmodl_filename = "/Users/salvadord/Documents/ISB/Models/M1_NetPyNE_CellReports_2023/sim/mod/h_kole.mod";
static const char* nmodl_file_text = 
  "TITLE Ih-current\n"
  ": modified from http://senselab.med.yale.edu/ModelDB/showmodel.cshtml?model=64195&file=%5cStochastic%5cStochastic_Na%5cih.mod\n"
  ": /u/samn/papers/jnsci_26_1677.pdf\n"
  ": \n"
  ": @article{kole2006single,\n"
  ":  title={Single Ih channels in pyramidal neuron dendrites: properties, distribution, and impact on action potential output},\n"
  ":  author={Kole, M.H.P. and Hallermann, S. and Stuart, G.J.},\n"
  ":  journal={The Journal of neuroscience},\n"
  ":  volume={26},\n"
  ":  number={6},\n"
  ":  pages={1677--1687},\n"
  ":  year={2006},\n"
  ":  publisher={Soc Neuroscience}\n"
  ": }\n"
  "\n"
  "COMMENT\n"
  "Author: Stefan Hallermann; modified by Sam Neymotin (parameterized)\n"
  "Provides deterministic Ih-currents as described in Kole et al. (2006).\n"
  "ENDCOMMENT\n"
  "\n"
  "UNITS {\n"
  "  (mA) = (milliamp)\n"
  "  (mV) = (millivolt)\n"
  "}\n"
  "\n"
  "PARAMETER {\n"
  "  v (mV)\n"
  "  erev=-45  		(mV) 	:ih-reversal potential			       \n"
  "  gbar=0.00015 	(S/cm2)	:default Ih conductance; exponential distribution is set in Ri18init.hoc \n"
  "  q10 = 2.2\n"
  "  ascale = 0.00643\n"
  "  bscale = 0.193\n"
  "  ashift = 154.9\n"
  "  aslope = 11.9\n"
  "  bslope = 33.1\n"
  "}\n"
  "\n"
  "NEURON {\n"
  " THREADSAFE\n"
  "  SUFFIX ih\n"
  "  NONSPECIFIC_CURRENT i\n"
  "  RANGE i,gbar,ascale,bscale,ashift,aslope,bslope\n"
  "}\n"
  "\n"
  "STATE {\n"
  "  m\n"
  "}\n"
  "\n"
  "ASSIGNED {\n"
  "  i (mA/cm2)\n"
  "}\n"
  "\n"
  "INITIAL { LOCAL a,b\n"
  "  a = alpha(v)\n"
  "  b = beta(v)\n"
  "  m = a / (a + b)\n"
  "}\n"
  "\n"
  "BREAKPOINT {\n"
  "  SOLVE state METHOD cnexp\n"
  "  i = gbar*m*(v-erev)\n"
  "}\n"
  "\n"
  ": tau = 1 / (alpha + beta)\n"
  "FUNCTION alpha(v(mV)) {\n"
  "  alpha = ascale*(v+ashift)/(exp((v+ashift)/aslope)-1)  \n"
  "  :parameters are estimated by direct fitting of HH model to activation time constants and voltage activation curve recorded at 34C\n"
  "}\n"
  "\n"
  "FUNCTION beta(v(mV)) {\n"
  "  beta = bscale*exp(v/bslope)\n"
  "}\n"
  "\n"
  "DERIVATIVE state {\n"
  "  m' = (1-m)*alpha(v) - m*beta(v)\n"
  "}\n"
  ;
#endif