proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD[4], axonstart, AIS, axon, axoD, axoD_sec[2]
create interD[3], interD_sec[6], nABD[7], nABD_sec[12]
proc topol() { local i
connect ABD(0), soma(1)
for i = 1, 3 connect ABD[i](0), ABD[i-1](1)
connect axonstart(0), ABD[3](1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
connect axoD(0), ABD[3](1)
for i = 0, 1 connect axoD_sec[i](0), axoD(1)
for i = 0, 2 connect interD[i](0), ABD[i](1)
for i = 0, 1 connect interD_sec[i](0), interD[1](1)
for i = 2, 3 connect interD_sec[i](0), interD_sec[1](1)
for i = 4, 5 connect interD_sec[i](0), interD[2](1)
for i = 0, 2 connect nABD[i](0), soma(0)
for i = 3, 4 connect nABD[i](0), soma(1)
for i = 5, 6 connect nABD[i](0), soma(0)
for i = 0, 1 connect nABD_sec[i](0), nABD[4](1)
for i = 2, 3 connect nABD_sec[i](0), nABD[6](1)
for i = 4, 5 connect nABD_sec[i](0), nABD[2](1)
for i = 6, 7 connect nABD_sec[i](0), nABD[1](1)
for i = 8, 9 connect nABD_sec[i](0), nABD_sec[7](1)
for i = 10, 11 connect nABD_sec[i](0), nABD[5](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
ABD {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(45, 0, 0, 1)}
ABD[1] {pt3dclear() pt3dadd(45, 0, 0, 1) pt3dadd(60, -14, 0, 1)}
ABD[2] {pt3dclear() pt3dadd(60, -14, 0, 1) pt3dadd(60, -44, 0, 1)}
ABD[3] {pt3dclear() pt3dadd(60, -44, 0, 1) pt3dadd(90, -44, 0, 1)}
axonstart {pt3dclear() pt3dadd(90, -44, 0, 1) pt3dadd(90, -14, 0, 1)}
AIS {pt3dclear() pt3dadd(90, -14, 0, 1) pt3dadd(105, 0, 0, 1)}
axon {pt3dclear() pt3dadd(105, 0, 0, 1) pt3dadd(150, 30, 0, 1)}
axoD {pt3dclear() pt3dadd(90, -44, 0, 1) pt3dadd(105, -59, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(105, -59, 0, 1) pt3dadd(135, -59, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(105, -59, 0, 1) pt3dadd(120, -74, 0, 1)}
interD {pt3dclear() pt3dadd(45, 0, 0, 1) pt3dadd(45, 30, 0, 1)}
interD[1] {pt3dclear() pt3dadd(60, -14, 0, 1) pt3dadd(75, 15, 0, 1)}
interD[2] {pt3dclear() pt3dadd(60, -44, 0, 1) pt3dadd(45, -59, 0, 1)}
interD_sec {pt3dclear() pt3dadd(75, 15, 0, 1) pt3dadd(75, 45, 0, 1)}
interD_sec[1] {pt3dclear() pt3dadd(75, 15, 0, 1) pt3dadd(105, 30, 0, 1)}
interD_sec[2] {pt3dclear() pt3dadd(105, 30, 0, 1) pt3dadd(105, 60, 0, 1)}
interD_sec[3] {pt3dclear() pt3dadd(105, 30, 0, 1) pt3dadd(135, 30, 0, 1)}
interD_sec[4] {pt3dclear() pt3dadd(45, -59, 0, 1) pt3dadd(60, -74, 0, 1)}
interD_sec[5] {pt3dclear() pt3dadd(45, -59, 0, 1) pt3dadd(30, -74, 0, 1)}
nABD {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-14, 30, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-29, 0, 0, 1)}
nABD[2] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-29, -29, 0, 1)}
nABD[3] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(15, 30, 0, 1)}
nABD[4] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(15, -29, 0, 1)}
nABD[5] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(0, 45, 0, 1)}
nABD[6] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(0, -44, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(15, -29, 0, 1) pt3dadd(0, -59, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(15, -29, 0, 1) pt3dadd(30, -44, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(0, -44, 0, 1) pt3dadd(-29, -44, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(0, -44, 0, 1) pt3dadd(-14, -59, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(-29, -29, 0, 1) pt3dadd(-59, -29, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(-29, -29, 0, 1) pt3dadd(-44, -44, 0, 1)}
nABD_sec[6] {pt3dclear() pt3dadd(-29, 0, 0, 1) pt3dadd(-44, 15, 0, 1)}
nABD_sec[7] {pt3dclear() pt3dadd(-29, 0, 0, 1) pt3dadd(-59, 0, 0, 1)}
nABD_sec[8] {pt3dclear() pt3dadd(-59, 0, 0, 1) pt3dadd(-74, 15, 0, 1)}
nABD_sec[9] {pt3dclear() pt3dadd(-59, 0, 0, 1) pt3dadd(-74, -14, 0, 1)}
nABD_sec[10] {pt3dclear() pt3dadd(0, 45, 0, 1) pt3dadd(15, 60, 0, 1)}
nABD_sec[11] {pt3dclear() pt3dadd(0, 45, 0, 1) pt3dadd(-14, 60, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
for i=0, 3 ABD[i] all.append()
axonstart all.append()
AIS all.append()
axon all.append()
axoD all.append()
for i=0, 1 axoD_sec[i] all.append()
for i=0, 2 interD[i] all.append()
for i=0, 5 interD_sec[i] all.append()
for i=0, 6 nABD[i] all.append()
for i=0, 11 nABD_sec[i] all.append()
all_biophys = new SectionList()
for i=0, 3 ABD[i] all_biophys.append()
axonstart all_biophys.append()
axoD all_biophys.append()
for i=0, 1 axoD_sec[i] all_biophys.append()
for i=0, 2 interD[i] all_biophys.append()
for i=0, 5 interD_sec[i] all_biophys.append()
for i=0, 6 nABD[i] all_biophys.append()
for i=0, 11 nABD_sec[i] all_biophys.append()
all_ABD = new SectionList()
axonstart all_ABD.append()
axoD all.append()
for i=0, 1 axoD_sec[i] all_ABD.append()
for i=0, 2 interD[i] all_ABD.append()
for i=0, 5 interD_sec[i] all_ABD.append()
for i=0, 3 ABD[i] all_ABD.append()
}
proc geom() {
soma { L = 42 }
ABD { L = 15 }
ABD[1] { L = 5 }
ABD[2] { L = 6 }
ABD[3] { L = 17 }
axonstart { L = 27.7 }
AIS { L = 33.9 }
axon { L = 800 }
axoD { L = 59 }
axoD_sec { L = 5 }
axoD_sec[1] { L = 9 }
interD { L = 67 }
interD[1] { L = 26 }
interD[2] { L = 30 }
interD_sec { L = 162 }
interD_sec[1] { L = 10 }
interD_sec[2] { L = 77 }
interD_sec[3] { L = 257 }
interD_sec[4] { L = 118 }
interD_sec[5] { L = 150 }
nABD { L = 32 }
nABD[1] { L = 32 }
nABD[2] { L = 29 }
nABD[3] { L = 38 }
nABD[4] { L = 24 }
nABD[5] { L = 17 }
nABD[6] { L = 58 }
nABD_sec { L = 238 }
nABD_sec[1] { L = 49 }
nABD_sec[2] { L = 51 }
nABD_sec[3] { L = 190 }
nABD_sec[4] { L = 3 }
nABD_sec[5] { L = 4 }
nABD_sec[6] { L = 16 }
nABD_sec[7] { L = 295 }
nABD_sec[8] { L = 13 }
nABD_sec[9] { L = 12 }
nABD_sec[10] { L = 217 }
nABD_sec[11] { L = 246 }
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10 }
ABD { diam(0:1) = 3.7:3 }
ABD[1] { diam(0:1) = 3:2.2 }
ABD[2] { diam(0:1) = 2.2:1.8 }
ABD[3] { diam(0:1) = 1.8:1.6 }
axonstart { diam(0:1) = 1.209:1.034 }
AIS { diam(0:1) = 1.034:0.585 }
axon { diam = 0.585 }
axoD { diam(0:1) = 0.856:0.7 }
axoD_sec { diam(0:1) = 0.7:0.5 }
axoD_sec[1] { diam(0:1) = 0.7:0.5 }
interD { diam(0:1) = 1.518:1 }
interD[1] { diam(0:1) = 1.917:1.5 }
interD[2] { diam(0:1) = 2.2: 1.5 }
interD_sec { diam(0:1) = 1.5:1 }
interD_sec[1] { diam(0:1) = 1.5:1 }
interD_sec[2] { diam(0:1) = 1:0.8 }
interD_sec[3] { diam(0:1) = 1:0.8 }
interD_sec[4] { diam(0:1) = 1.5:1 }
interD_sec[5] { diam(0:1) = 1.5:1 }
nABD { diam(0:1) = 1:0.8 }
nABD[1] { diam(0:1) = 1.3:1 }
nABD[2] { diam(0:1) = 1.7:1.5 }
nABD[3] { diam(0:1) = 1.6:1.3 }
nABD[4] { diam(0:1) = 1.3:1 }
nABD[5] { diam(0:1) = 1.8:1.5 }
nABD[6] { diam(0:1) = 2.5:2 }
nABD_sec { diam = 1 }
nABD_sec[1] { diam(0:1) = 1:08 }
nABD_sec[2] { diam = 1.5 }
nABD_sec[3] { diam = 1.5 }
nABD_sec[4] { diam = 1.3 }
nABD_sec[5] { diam = 1.3 }
nABD_sec[6] { diam = 1 }
nABD_sec[7] { diam =0.8 }
nABD_sec[8] { diam = 0.8 }
nABD_sec[9] { diam = 0.8 }
nABD_sec[10] { diam = 1 }
nABD_sec[11] { diam = 1 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
}
forsec all_biophys {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert kca
gbar_kca = 0.1
insert cad
insert Na12
gbar_Na12 = 75
insert kdrDA
gbar_kdrDA = 150
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert Ih
gbar_Ih = 3
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
AIS {
insert Na12
gbar_Na12 = 4000
insert kdrDA
gbar_kdrDA = 4000
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
axon {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert Na12
gbar_Na12 = 400
insert kdrDA
gbar_kdrDA = 400
}
forsec all { ena=60
ek=-90}
}
access soma
celldef()