proc celldef() {
topol()
subsets()
geom()
biophys()
}
create soma, ABD[4], interD[3], interD_sec[2], axonstart, AIS, axon
create axoD, nABD[3], nABD_sec[23]
proc topol() { local i
connect ABD(0), soma(1)
for i = 1, 3 connect ABD[i](0), ABD[i-1](1)
for i = 0, 2 connect interD[i](0), ABD[i](1)
for i = 0, 1 connect interD_sec[i](0), interD(1)
connect axonstart(0), ABD[3](1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
connect axoD(0), ABD[3](1)
for i = 0, 2 connect nABD[i](0), soma(0)
for i = 0, 1 connect nABD_sec[i](0), nABD[2](1)
for i = 2, 3 connect nABD_sec[i](0), nABD[1](1)
for i = 4, 5 connect nABD_sec[i](0), nABD_sec[3](1)
for i = 6, 7 connect nABD_sec[i](0), nABD_sec[5](1)
for i = 8, 9 connect nABD_sec[i](0), nABD(1)
for i = 10, 11 connect nABD_sec[i](0), nABD_sec[9](1)
for i = 12, 13 connect nABD_sec[i](0), nABD_sec[11](1)
for i = 14, 16 connect nABD_sec[i](0), nABD_sec[10](1)
for i = 17, 18 connect nABD_sec[i](0), nABD_sec[14](1)
for i = 19, 20 connect nABD_sec[i](0), nABD_sec[15](1)
for i = 21, 22 connect nABD_sec[i](0), nABD_sec[16](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
ABD {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(45, 15, 0, 1)}
ABD[1] {pt3dclear() pt3dadd(45, 15, 0, 1) pt3dadd(90, 0, 0, 1)}
ABD[2] {pt3dclear() pt3dadd(90, 0, 0, 1) pt3dadd(105, 30, 0, 1)}
ABD[3] {pt3dclear() pt3dadd(105, 30, 0, 1) pt3dadd(150, 30, 0, 1)}
interD {pt3dclear() pt3dadd(45, 15, 0, 1) pt3dadd(45, 45, 0, 1)}
interD[1] {pt3dclear() pt3dadd(90, 0, 0, 1) pt3dadd(135, -29, 0, 1)}
interD[2] {pt3dclear() pt3dadd(105, 30, 0, 1) pt3dadd(90, 60, 0, 1)}
interD_sec {pt3dclear() pt3dadd(45, 45, 0, 1) pt3dadd(15, 60, 0, 1)}
interD_sec[1] {pt3dclear() pt3dadd(45, 45, 0, 1) pt3dadd(60, 75, 0, 1)}
axonstart {pt3dclear() pt3dadd(150, 30, 0, 1) pt3dadd(165, 15, 0, 1)}
AIS {pt3dclear() pt3dadd(165, 15, 0, 1) pt3dadd(180, 0, 0, 1)}
axon {pt3dclear() pt3dadd(180, 0, 0, 1) pt3dadd(225, -44, 0, 1)}
axoD {pt3dclear() pt3dadd(150, 30, 0, 1) pt3dadd(180, 60, 0, 1)}
nABD {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(0, -59, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-89, 0, 0, 1)}
nABD[2] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-29, 60, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(-29, 60, 0, 1) pt3dadd(-14, 90, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(-29, 60, 0, 1) pt3dadd(-59, 75, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(-89, 0, 0, 1) pt3dadd(-104, 30, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(-89, 0, 0, 1) pt3dadd(-119, -29, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(-119, -29, 0, 1) pt3dadd(-149, -14, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(-119, -29, 0, 1) pt3dadd(-119, -59, 0, 1)}
nABD_sec[6] {pt3dclear() pt3dadd(-119, -59, 0, 1) pt3dadd(-149, -74, 0, 1)}
nABD_sec[7] {pt3dclear() pt3dadd(-119, -59, 0, 1) pt3dadd(-89, -74, 0, 1)}
nABD_sec[8] {pt3dclear() pt3dadd(0, -59, 0, 1) pt3dadd(-14, -89, 0, 1)}
nABD_sec[9] {pt3dclear() pt3dadd(0, -59, 0, 1) pt3dadd(45, -89, 0, 1)}
nABD_sec[10] {pt3dclear() pt3dadd(45, -89, 0, 1) pt3dadd(30, -134, 0, 1)}
nABD_sec[11] {pt3dclear() pt3dadd(45, -89, 0, 1) pt3dadd(90, -104, 0, 1)}
nABD_sec[12] {pt3dclear() pt3dadd(90, -104, 0, 1) pt3dadd(135, -89, 0, 1)}
nABD_sec[13] {pt3dclear() pt3dadd(90, -104, 0, 1) pt3dadd(105, -134, 0, 1)}
nABD_sec[14] {pt3dclear() pt3dadd(30, -134, 0, 1) pt3dadd(-14, -149, 0, 1)}
nABD_sec[15] {pt3dclear() pt3dadd(30, -134, 0, 1) pt3dadd(30, -179, 0, 1)}
nABD_sec[16] {pt3dclear() pt3dadd(30, -134, 0, 1) pt3dadd(75, -164, 0, 1)}
nABD_sec[17] {pt3dclear() pt3dadd(-14, -149, 0, 1) pt3dadd(-59, -149, 0, 1)}
nABD_sec[18] {pt3dclear() pt3dadd(-14, -149, 0, 1) pt3dadd(-14, -194, 0, 1)}
nABD_sec[19] {pt3dclear() pt3dadd(30, -179, 0, 1) pt3dadd(15, -209, 0, 1)}
nABD_sec[20] {pt3dclear() pt3dadd(30, -179, 0, 1) pt3dadd(75, -224, 0, 1)}
nABD_sec[21] {pt3dclear() pt3dadd(75, -164, 0, 1) pt3dadd(120, -164, 0, 1)}
nABD_sec[22] {pt3dclear() pt3dadd(75, -164, 0, 1) pt3dadd(90, -209, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
for i=0, 3 ABD[i] all.append()
for i=0, 2 interD[i] all.append()
for i=0, 1 interD_sec[i] all.append()
axonstart all.append()
AIS all.append()
axon all.append()
axoD all.append()
for i=0, 2 nABD[i] all.append()
for i=0, 22 nABD_sec[i] all.append()
all_biophys = new SectionList()
for i=0, 3 ABD[i] all_biophys.append()
for i=0, 2 interD[i] all_biophys.append()
for i=0, 1 interD_sec[i] all_biophys.append()
axonstart all_biophys.append()
axoD all_biophys.append()
for i=0, 2 nABD[i] all_biophys.append()
for i=0, 22 nABD_sec[i] all_biophys.append()
all_ABD= new SectionList()
for i=0, 3 ABD[i] all_ABD.append()
for i=0, 2 interD[i] all_ABD.append()
for i=0, 1 interD_sec[i] all_ABD.append()
axonstart all_ABD.append()
axoD all_ABD.append()
}
proc geom() {
soma { L = 37 }
ABD { L = 16 }
ABD[1] { L = 10 }
ABD[2] { L = 50 }
ABD[3] { L = 19 }
interD { L = 208 }
interD[1] { L = 418 }
interD[2] { L = 15 }
interD_sec { L = 267 }
interD_sec[1] { L = 319 }
axonstart { L = 21.2 }
AIS { L = 30.5 }
axon { L = 800 }
axoD { L = 33 }
nABD { L = 32 }
nABD[1] { L = 14 }
nABD[2] { L = 21 }
nABD_sec { L = 261 }
nABD_sec[1] { L = 150 }
nABD_sec[2] { L = 101 }
nABD_sec[3] { L = 47 }
nABD_sec[4] { L = 338 }
nABD_sec[5] { L = 362 }
nABD_sec[6] { L = 30 }
nABD_sec[7] { L = 36 }
nABD_sec[8] { L = 112 }
nABD_sec[9] { L = 18 }
nABD_sec[10] { L = 318 }
nABD_sec[11] { L = 204 }
nABD_sec[12] { L = 119 }
nABD_sec[13] { L = 134 }
nABD_sec[14] { L = 21 }
nABD_sec[15] { L = 108 }
nABD_sec[16] { L = 45 }
nABD_sec[17] { L = 204 }
nABD_sec[18] { L = 130 }
nABD_sec[19] { L = 30 }
nABD_sec[20] { L = 10 }
nABD_sec[21] { L = 291 }
nABD_sec[22] { L = 83 }
//nseg
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10 }
ABD { diam(0:1) = 3.25:3.25 }
ABD[1] { diam(0:1) = 3.25:1.8 }
ABD[2] { diam(0:1) = 1.8:1.5 }
ABD[3] { diam(0:1) = 1.5:1.3 }
interD { diam(0:1) = 1.3:1}
interD[1] { diam(0:1) = 1.73:1 }
interD[2] { diam(0:1) = 1.23:1 }
interD_sec { diam = 0.8 }
interD_sec[1] { diam = 0.8 }
axonstart { diam(0:1) = 1.45:1.26 }
AIS { diam(0:1) = 1.26:1.04 }
axon { diam = 1.04 }
axoD { diam(0:1) = 1.8:1 }
nABD { diam(0:1) = 4:3.5 }
nABD[1] { diam(0:1) = 2.7:2.5 }
nABD[2] { diam(0:1) = 2.1:1.9 }
nABD_sec { diam(0:1) = 1:08 }
nABD_sec[1] { diam(0:1) = 1:08 }
nABD_sec[2] { diam(0:1) = 1:0.8 }
nABD_sec[3] { diam(0:1) = 1.5:1 }
nABD_sec[4] { diam(0:1) = 1:0.8 }
nABD_sec[5] { diam = 1 }
nABD_sec[6] { diam = 0.8 }
nABD_sec[7] { diam = 0.8 }
nABD_sec[8] { diam(0:1) = 2:1 }
nABD_sec[9] { diam = 2 }
nABD_sec[10] { diam = 1.5 }
nABD_sec[11] { diam = 1 }
nABD_sec[12] { diam = 0.8 }
nABD_sec[13] { diam = 0.8 }
nABD_sec[14] { diam = 1 }
nABD_sec[15] { diam = 1 }
nABD_sec[16] { diam = 1 }
nABD_sec[17] { diam = 0.8 }
nABD_sec[18] { diam = 0.8 }
nABD_sec[19] { diam = 0.8 }
nABD_sec[20] { diam = 0.8 }
nABD_sec[21] { diam = 0.8 }
nABD_sec[22] { diam = 0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
}
forsec all_biophys {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert Na12
gbar_Na12 = 75
insert kdrDA
gbar_kdrDA = 150
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert Ih
gbar_Ih = 3
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert kca
gbar_kca = 0.1
insert Na12
gbar_Na12 = 75
insert cad
insert kdrDA
gbar_kdrDA = 150
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert Ih
gbar_Ih = 3
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
}
AIS {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert Na12
gbar_Na12 = 4000
insert kdrDA
gbar_kdrDA = 4000
}
axon {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert Na12
gbar_Na12 = 400
insert kdrDA
gbar_kdrDA = 400
}
forsec all { ek=-90
ena=60 }
}
access soma
celldef()