proc celldef() {
topol()
subsets()
geom()
biophys()
}
create soma, ABD, axonstart, AIS, axon, axoD[2], axoD_sec[4]
create nABD[4], nABD_sec[14]
proc topol() { local i
connect ABD(0), soma(1)
connect axonstart(0), ABD(1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
for i = 0, 1 connect axoD[i](0), ABD(1)
for i = 0, 1 connect axoD_sec[i](0), axoD(1)
for i = 2, 3 connect axoD_sec[i](0), axoD[1](1)
for i = 0, 3 connect nABD[i](0), soma(0)
for i = 0, 1 connect nABD_sec[i](0), nABD[1](1)
for i = 2, 5 connect nABD_sec[i](0), nABD_sec(1)
for i = 6, 7 connect nABD_sec[i](0), nABD_sec[1](1)
for i = 8, 9 connect nABD_sec[i](0), nABD_sec[6](1)
for i = 10, 11 connect nABD_sec[i](0), nABD[3](1)
for i = 12, 13 connect nABD_sec[i](0), nABD_sec[11](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
ABD {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(60, 0, 0, 1)}
axonstart {pt3dclear() pt3dadd(60, 0, 0, 1) pt3dadd(90, 30, 0, 1)}
AIS {pt3dclear() pt3dadd(90, 30, 0, 1) pt3dadd(120, 60, 0, 1)}
axon {pt3dclear() pt3dadd(120, 60, 0, 1) pt3dadd(195, 150, 0, 1)}
axoD {pt3dclear() pt3dadd(60, 0, 0, 1) pt3dadd(60, -59, 0, 1)}
axoD[1] {pt3dclear() pt3dadd(60, 0, 0, 1) pt3dadd(120, -29, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(60, -59, 0, 1) pt3dadd(45, -89, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(60, -59, 0, 1) pt3dadd(90, -74, 0, 1)}
axoD_sec[2] {pt3dclear() pt3dadd(120, -29, 0, 1) pt3dadd(165, -14, 0, 1)}
axoD_sec[3] {pt3dclear() pt3dadd(120, -29, 0, 1) pt3dadd(135, -74, 0, 1)}
nABD {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-14, 60, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-59, 45, 0, 1)}
nABD[2] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-74, -44, 0, 1)}
nABD[3] {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(0, -89, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(-59, 45, 0, 1) pt3dadd(-59, 90, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(-59, 45, 0, 1) pt3dadd(-104, 30, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(-59, 90, 0, 1) pt3dadd(-14, 105, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(-59, 90, 0, 1) pt3dadd(-59, 135, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(-59, 90, 0, 1) pt3dadd(-89, 135, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(-59, 90, 0, 1) pt3dadd(-104, 90, 0, 1)}
nABD_sec[6] {pt3dclear() pt3dadd(-104, 30, 0, 1) pt3dadd(-119, -14, 0, 1)}
nABD_sec[7] {pt3dclear() pt3dadd(-104, 30, 0, 1) pt3dadd(-134, 60, 0, 1)}
nABD_sec[8] {pt3dclear() pt3dadd(-119, -14, 0, 1) pt3dadd(-164, -29, 0, 1)}
nABD_sec[9] {pt3dclear() pt3dadd(-119, -14, 0, 1) pt3dadd(-104, -44, 0, 1)}
nABD_sec[10] {pt3dclear() pt3dadd(0, -89, 0, 1) pt3dadd(-29, -119, 0, 1)}
nABD_sec[11] {pt3dclear() pt3dadd(0, -89, 0, 1) pt3dadd(15, -149, 0, 1)}
nABD_sec[12] {pt3dclear() pt3dadd(15, -149, 0, 1) pt3dadd(0, -179, 0, 1)}
nABD_sec[13] {pt3dclear() pt3dadd(15, -149, 0, 1) pt3dadd(60, -164, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
ABD all.append()
axonstart all.append()
AIS all.append()
axon all.append()
for i=0, 1 axoD[i] all.append()
for i=0, 3 axoD_sec[i] all.append()
for i=0, 3 nABD[i] all.append()
for i=0, 13 nABD_sec[i] all.append()
all_biophys = new SectionList()
ABD all_biophys.append()
axonstart all_biophys.append()
for i=0, 1 axoD[i] all_biophys.append()
for i=0, 3 axoD_sec[i] all_biophys.append()
for i=0, 3 nABD[i] all_biophys.append()
for i=0, 13 nABD_sec[i] all_biophys.append()
all_ABD =new SectionList()
ABD all_ABD.append()
axonstart all_ABD.append()
for i=0, 1 axoD[i] all_ABD.append()
for i=0, 3 axoD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 30 }
ABD { L = 7 }
axonstart { L = 24.1 }
AIS { L = 30 }
axon { L = 800 }
axoD { L = 35 }
axoD[1] { L = 65 }
axoD_sec { L = 423 }
axoD_sec[1] { L = 249 }
axoD_sec[2] { L = 172 }
axoD_sec[3] { L = 185 }
nABD { L = 466 }
nABD[1] { L = 8 }
nABD[2] { L = 36 }
nABD[3] { L = 60 }
nABD_sec { L = 16 }
nABD_sec[1] { L = 72 }
nABD_sec[2] { L = 73 }
nABD_sec[3] { L = 422 }
nABD_sec[4] { L = 195 }
nABD_sec[5] { L = 403 }
nABD_sec[6] { L = 45 }
nABD_sec[7] { L = 184 }
nABD_sec[8] { L = 288 }
nABD_sec[9] { L = 324 }
nABD_sec[10] { L = 108 }
nABD_sec[11] { L = 58 }
nABD_sec[12] { L = 145 }
nABD_sec[13] { L = 172 }
// nseg definition has to be launched before diam definition for tapering to be taken into account
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam =10 }
ABD { diam = 3.35 }
axonstart { diam(0:1) = 2.03:1.6 }
AIS { diam(0:1) = 1.6:1.25 }
axon { diam = 1.25 }
axoD { diam(0:1) = 1.5:1 }
axoD[1] { diam(0:1) = 1.3:1 }
axoD_sec { diam(0:1) = 1:0.8 }
axoD_sec[1] { diam(0:1) = 1:0.8 }
axoD_sec[2] { diam(0:1) = 1:0.8 }
axoD_sec[3] { diam(0:1) = 1:0.8 }
nABD { diam(0:1) = 1.3:0.8 }
nABD[1] { diam(0:1) = 5.7:5 }
nABD[2] { diam(0:1) = 1.7:1 }
nABD[3] { diam(0:1) = 2.1:1.8 }
nABD_sec { diam = 3 }
nABD_sec[1] { diam(0:1) = 2:1.5 }
nABD_sec[2] { diam = 0.8 }
nABD_sec[3] { diam = 0.8 }
nABD_sec[4] { diam = 0.8 }
nABD_sec[5] { diam = 0.8 }
nABD_sec[6] { diam = 1 }
nABD_sec[7] { diam = 0.8 }
nABD_sec[8] { diam = 0.8 }
nABD_sec[9] { diam = 0.8 }
nABD_sec[10] { diam = 0.8 }
nABD_sec[11] { diam = 1 }
nABD_sec[12] { diam = 0.8 }
nABD_sec[13] { diam = 0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
}
forsec all_biophys {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert kca
gbar_kca = 0.1
insert cad
insert Na12
gbar_Na12 = 75
insert kdrDA
gbar_kdrDA = 150
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert Ih
gbar_Ih = 3
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
}
soma {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert kca
gbar_kca = 0.1
insert cad
insert Na12
gbar_Na12 = 75
insert kdrDA
gbar_kdrDA = 150
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert Ih
gbar_Ih = 3
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
}
AIS {
insert Na12
gbar_Na12 = 4000
insert kdrDA
gbar_kdrDA = 4000
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
axon {
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
insert Na12
gbar_Na12 = 400
insert kdrDA
gbar_kdrDA = 400
}
forsec all {ena=60
ek=-90 }
}
access soma
celldef()