proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD[4], axonstart, AIS, axon, axoD[2], axoD_sec[6]
create interD[3], interD_sec[2], nABD[2], nABD_sec[4]
proc topol() { local i
connect ABD(0), soma(0)
for i = 1, 3 connect ABD[i](0), ABD[i-1](1)
connect axonstart(0), ABD[3](1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
for i = 0, 1 connect axoD[i](0), ABD[3](1)
for i = 0, 1 connect axoD_sec[i](0), axoD(1)
for i = 2, 3 connect axoD_sec[i](0), axoD[1](1)
for i = 4, 5 connect axoD_sec[i](0), axoD_sec[3](1)
for i = 0, 2 connect interD[i](0), ABD[i](1)
for i = 0, 1 connect interD_sec[i](0), interD(1)
for i = 0, 1 connect nABD[i](0), soma(1)
for i = 0, 1 connect nABD_sec[i](0), nABD[1](1)
for i = 2, 3 connect nABD_sec[i](0), nABD_sec[1](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
ABD {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(0, 45, 0, 1)}
ABD[1] {pt3dclear() pt3dadd(0, 45, 0, 1) pt3dadd(30, 60, 0, 1)}
ABD[2] {pt3dclear() pt3dadd(30, 60, 0, 1) pt3dadd(60, 75, 0, 1)}
ABD[3] {pt3dclear() pt3dadd(60, 75, 0, 1) pt3dadd(90, 90, 0, 1)}
axonstart {pt3dclear() pt3dadd(90, 90, 0, 1) pt3dadd(105, 60, 0, 1)}
AIS {pt3dclear() pt3dadd(105, 60, 0, 1) pt3dadd(120, 30, 0, 1)}
axon {pt3dclear() pt3dadd(120, 30, 0, 1) pt3dadd(165, -44, 0, 1)}
axoD {pt3dclear() pt3dadd(90, 90, 0, 1) pt3dadd(90, 120, 0, 1)}
axoD[1] {pt3dclear() pt3dadd(90, 90, 0, 1) pt3dadd(120, 90, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(90, 120, 0, 1) pt3dadd(75, 150, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(90, 120, 0, 1) pt3dadd(105, 150, 0, 1)}
axoD_sec[2] {pt3dclear() pt3dadd(120, 90, 0, 1) pt3dadd(135, 120, 0, 1)}
axoD_sec[3] {pt3dclear() pt3dadd(120, 90, 0, 1) pt3dadd(150, 75, 0, 1)}
axoD_sec[4] {pt3dclear() pt3dadd(150, 75, 0, 1) pt3dadd(165, 45, 0, 1)}
axoD_sec[5] {pt3dclear() pt3dadd(150, 75, 0, 1) pt3dadd(180, 75, 0, 1)}
interD {pt3dclear() pt3dadd(0, 45, 0, 1) pt3dadd(-29, 60, 0, 1)}
interD[1] {pt3dclear() pt3dadd(30, 60, 0, 1) pt3dadd(15, 90, 0, 1)}
interD[2] {pt3dclear() pt3dadd(60, 75, 0, 1) pt3dadd(45, 105, 0, 1)}
interD_sec {pt3dclear() pt3dadd(-29, 60, 0, 1) pt3dadd(-44, 90, 0, 1)}
interD_sec[1] {pt3dclear() pt3dadd(-29, 60, 0, 1) pt3dadd(-59, 45, 0, 1)}
nABD {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(75, 0, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(15, -59, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(15, -59, 0, 1) pt3dadd(0, -89, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(15, -59, 0, 1) pt3dadd(45, -89, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(45, -89, 0, 1) pt3dadd(90, -89, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(45, -89, 0, 1) pt3dadd(45, -134, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
for i=0, 3 ABD[i] all.append()
axonstart all.append()
AIS all.append()
axon all.append()
for i=0, 1 axoD[i] all.append()
for i=0, 5 axoD_sec[i] all.append()
for i=0, 2 interD[i] all.append()
for i=0, 1 interD_sec[i] all.append()
for i=0, 1 nABD[i] all.append()
for i=0, 3 nABD_sec[i] all.append()
all_biophys = new SectionList()
for i=0, 3 ABD[i] all_biophys.append()
axonstart all_biophys.append()
for i=0, 1 axoD[i] all_biophys.append()
for i=0, 5 axoD_sec[i] all_biophys.append()
for i=0, 2 interD[i] all_biophys.append()
for i=0, 1 interD_sec[i] all_biophys.append()
for i=0, 1 nABD[i] all_biophys.append()
for i=0, 3 nABD_sec[i] all_biophys.append()
all_ABD=new SectionList()
for i=0, 3 ABD[i] all_ABD.append()
axonstart all_ABD.append()
for i=0, 1 axoD[i] all_ABD.append()
for i=0, 5 axoD_sec[i] all_ABD.append()
for i=0, 2 interD[i] all_ABD.append()
for i=0, 1 interD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 12 }
ABD { L = 9 }
ABD[1] { L = 23 }
ABD[2] { L = 4 }
ABD[3] { L = 14 }
axonstart { L = 14 }
AIS { L = 33.6 }
axon { L = 800 }
axoD { L = 5 }
axoD[1] { L = 11 }
axoD_sec { L = 23 }
axoD_sec[1] { L = 6 }
axoD_sec[2] { L = 150 }
axoD_sec[3] { L = 145 }
axoD_sec[4] { L = 26 }
axoD_sec[5] { L = 44 }
interD { L = 28 }
interD[1] { L = 81 }
interD[2] { L = 102 }
interD_sec { L = 149 }
interD_sec[1] { L = 158 }
nABD { L = 100 }
nABD[1] { L = 35 }
nABD_sec { L = 51 }
nABD_sec[1] { L = 28 }
nABD_sec[2] { L = 118 }
nABD_sec[3] { L = 46 }
//nseg
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10}
ABD { diam = 3.7 }
ABD[1] { diam(0:1) = 3.7:2.9 }
ABD[2] { diam(0:1) = 2.9:2 }
ABD[3] { diam = 2 }
axonstart { diam(0:1) = 1.26:0.9 }
AIS { diam(0:1) = 0.9:06 }
axon { diam = 0.6 }
axoD { diam = 0.8 }
axoD[1] { diam = 1.2 }
axoD_sec { diam = 0.8 }
axoD_sec[1] { diam = 0.8 }
axoD_sec[2] { diam = 0.8 }
axoD_sec[3] { diam(0:1) = 1:0.8 }
axoD_sec[4] { diam = 0.8 }
axoD_sec[5] { diam = 0.8 }
interD { diam(0:1) = 1.8:1.5 }
interD[1] { diam = 0.8 }
interD[2] { diam(0:1) = 1.3:0.8 }
interD_sec { diam(0:1) = 1:0.8 }
interD_sec[1] { diam(0:1) = 1:0.8 }
nABD { diam(0:1) = 1:0.8 }
nABD[1] { diam(0:1) = 3.5:3 }
nABD_sec { diam(0:1) = 1:0.8 }
nABD_sec[1] { diam(0:1) = 2:1.5 }
nABD_sec[2] { diam(0:1) = 1:0.8 }
nABD_sec[3] { diam = 0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
forsec all_biophys {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
AIS {
insert kdrDA
gbar_kdrDA = 4000
insert Na12
gbar_Na12 = 4000
}
axon {
insert kdrDA
gbar_kdrDA = 400
insert Na12
gbar_Na12 = 400
}
forsec all {ena=60
ek=-90}
}
access soma
celldef()