proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD, axonstart, AIS, axon, axoD[3], axoD_sec[8]
create nABD[3], nABD_sec[11]
proc topol() { local i
connect ABD(0), soma(0)
connect axonstart(0), ABD(1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
for i = 0, 2 connect axoD[i](0), ABD(1)
for i = 0, 1 connect axoD_sec[i](0), axoD[1](1)
for i = 2, 3 connect axoD_sec[i](0), axoD_sec[1](1)
for i = 4, 5 connect axoD_sec[i](0), axoD_sec[3](1)
for i = 6, 7 connect axoD_sec[i](0), axoD_sec[5](1)
for i = 0, 2 connect nABD[i](0), soma(1)
for i = 0, 1 connect nABD_sec[i](0), nABD[2](1)
for i = 2, 3 connect nABD_sec[i](0), nABD_sec[1](1)
for i = 4, 5 connect nABD_sec[i](0), nABD_sec(1)
for i = 6, 7 connect nABD_sec[i](0), nABD[1](1)
for i = 8, 9 connect nABD_sec[i](0), nABD(1)
connect nABD_sec[10](0), nABD_sec(1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 15, 0, 1) pt3dadd(15, 15, 0, 1)}
ABD {pt3dclear() pt3dadd(0, 15, 0, 1) pt3dadd(-29, 0, 0, 1)}
axonstart {pt3dclear() pt3dadd(-29, 0, 0, 1) pt3dadd(-14, -14, 0, 1)}
AIS {pt3dclear() pt3dadd(-14, -14, 0, 1) pt3dadd(15, -44, 0, 1)}
axon {pt3dclear() pt3dadd(15, -44, 0, 1) pt3dadd(60, -89, 0, 1)}
axoD {pt3dclear() pt3dadd(-29, 0, 0, 1) pt3dadd(-59, 15, 0, 1)}
axoD[1] {pt3dclear() pt3dadd(-29, 0, 0, 1) pt3dadd(-59, -14, 0, 1)}
axoD[2] {pt3dclear() pt3dadd(-29, 0, 0, 1) pt3dadd(-29, -29, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(-59, -14, 0, 1) pt3dadd(-89, -14, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(-59, -14, 0, 1) pt3dadd(-74, -44, 0, 1)}
axoD_sec[2] {pt3dclear() pt3dadd(-74, -44, 0, 1) pt3dadd(-104, -44, 0, 1)}
axoD_sec[3] {pt3dclear() pt3dadd(-74, -44, 0, 1) pt3dadd(-59, -74, 0, 1)}
axoD_sec[4] {pt3dclear() pt3dadd(-59, -74, 0, 1) pt3dadd(-29, -89, 0, 1)}
axoD_sec[5] {pt3dclear() pt3dadd(-59, -74, 0, 1) pt3dadd(-59, -104, 0, 1)}
axoD_sec[6] {pt3dclear() pt3dadd(-59, -104, 0, 1) pt3dadd(-74, -119, 0, 1)}
axoD_sec[7] {pt3dclear() pt3dadd(-59, -104, 0, 1) pt3dadd(-44, -119, 0, 1)}
nABD {pt3dclear() pt3dadd(15, 15, 0, 1) pt3dadd(-14, 60, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(15, 15, 0, 1) pt3dadd(60, 45, 0, 1)}
nABD[2] {pt3dclear() pt3dadd(15, 15, 0, 1) pt3dadd(45, -14, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(45, -14, 0, 1) pt3dadd(75, 0, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(45, -14, 0, 1) pt3dadd(60, -44, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(60, -44, 0, 1) pt3dadd(60, -74, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(60, -44, 0, 1) pt3dadd(90, -59, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(75, 0, 0, 1) pt3dadd(90, 30, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(75, 0, 0, 1) pt3dadd(105, -14, 0, 1)}
nABD_sec[6] {pt3dclear() pt3dadd(60, 45, 0, 1) pt3dadd(60, 75, 0, 1)}
nABD_sec[7] {pt3dclear() pt3dadd(60, 45, 0, 1) pt3dadd(90, 45, 0, 1)}
nABD_sec[8] {pt3dclear() pt3dadd(-14, 60, 0, 1) pt3dadd(-14, 90, 0, 1)}
nABD_sec[9] {pt3dclear() pt3dadd(-14, 60, 0, 1) pt3dadd(-44, 75, 0, 1)}
nABD_sec[10] {pt3dclear() pt3dadd(75, 0, 0, 1) pt3dadd(105, 15, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
ABD all.append()
axonstart all.append()
AIS all.append()
axon all.append()
for i=0, 2 axoD[i] all.append()
for i=0, 7 axoD_sec[i] all.append()
for i=0, 2 nABD[i] all.append()
for i=0, 10 nABD_sec[i] all.append()
all_biophys = new SectionList()
ABD all_biophys.append()
axonstart all_biophys.append()
for i=0, 2 axoD[i] all_biophys.append()
for i=0, 7 axoD_sec[i] all_biophys.append()
for i=0, 2 nABD[i] all_biophys.append()
for i=0, 10 nABD_sec[i] all_biophys.append()
all_ABD=new SectionList()
ABD all_ABD.append()
axonstart all_ABD.append()
for i=0, 2 axoD[i] all_ABD.append()
for i=0, 7 axoD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 33 }
ABD { L = 4 }
axonstart { L = 21 }
AIS { L = 29.6 }
axon { L = 800 }
axoD { L = 70 }
axoD[1] { L = 3 }
axoD[2] { L = 25 }
axoD_sec { L = 199 }
axoD_sec[1] { L = 54 }
axoD_sec[2] { L = 185 }
axoD_sec[3] { L = 70 }
axoD_sec[4] { L = 54 }
axoD_sec[5] { L = 7 }
axoD_sec[6] { L = 30 }
axoD_sec[7] { L = 63 }
nABD { L = 9 }
nABD[1] { L = 3 }
nABD[2] { L = 17 }
nABD_sec { L = 7 }
nABD_sec[1] { L = 37 }
nABD_sec[2] { L = 306 }
nABD_sec[3] { L = 395 }
nABD_sec[4] { L = 221 }
nABD_sec[5] { L = 181 }
nABD_sec[6] { L = 18 }
nABD_sec[7] { L = 45 }
nABD_sec[8] { L = 166 }
nABD_sec[9] { L = 136 }
nABD_sec[10] { L = 170 }
// nseg definition has to be launched before diam definition for tapering to be taken into account
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10 }
ABD { diam(0:1) = 2.6:2.2 }
axonstart { diam(0:1) = 1.2:1.1 }
AIS { diam(0:1) = 1.1:0.75 }
axon { diam = 0.75 }
axoD { diam(0:1) = 1.2:1 }
axoD[1] { diam(0:1) = 1.8:1.5 }
axoD[2] { diam(0:1) = 1:0.8 }
axoD_sec { diam(0:1) = 1:0.8 }
axoD_sec[1] { diam = 1 }
axoD_sec[2] { diam = 0.8 }
axoD_sec[3] { diam = 1 }
axoD_sec[4] { diam = 0.8 }
axoD_sec[5] { diam = 1 }
axoD_sec[6] { diam = 0.8 }
axoD_sec[7] { diam = 0.8 }
nABD { diam(0:1) = 2.2:2 }
nABD[1] { diam(0:1) = 2.5:2 }
nABD[2] { diam(0:1) = 3:2.5 }
nABD_sec { diam = 2 }
nABD_sec[1] { diam = 1 }
nABD_sec[2] { diam = 0.8 }
nABD_sec[3] { diam = 0.8 }
nABD_sec[4] { diam(0:1) = 1:0.8 }
nABD_sec[5] { diam(0:1) = 1:0.8 }
nABD_sec[6] { diam(0:1) = 1:0.8 }
nABD_sec[7] { diam(0:1) = 1:0.8 }
nABD_sec[8] { diam(0:1) = 1:0.8 }
nABD_sec[9] { diam(0:1) = 1:0.8 }
nABD_sec[10] { diam(0:1) = 1:0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
forsec all_biophys {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
AIS {
insert kdrDA
gbar_kdrDA = 4000
insert Na12
gbar_Na12 = 4000
}
axon {
insert kdrDA
gbar_kdrDA = 400
insert Na12
gbar_Na12 = 400
}
forsec all { ek=-90
ena=60 }
}
access soma
celldef()