proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD, axonstart, AIS, axon, axoD[4], axoD_sec[2]
create nABD[4], nABD_sec[12]
proc topol() { local i
connect ABD(0), soma(0)
connect axonstart(0), ABD(1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
for i = 0, 3 connect axoD[i](0), ABD(1)
for i = 0, 1 connect axoD_sec[i](0), axoD(1)
for i = 0, 3 connect nABD[i](0), soma(1)
for i = 0, 1 connect nABD_sec[i](0), nABD(1)
for i = 2, 3 connect nABD_sec[i](0), nABD_sec[1](1)
for i = 4, 5 connect nABD_sec[i](0), nABD[2](1)
for i = 6, 7 connect nABD_sec[i](0), nABD_sec[4](1)
for i = 8, 9 connect nABD_sec[i](0), nABD_sec[5](1)
for i = 10, 11 connect nABD_sec[i](0), nABD[3](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
ABD {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(0, 30, 0, 1)}
axonstart {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(-29, 30, 0, 1)}
AIS {pt3dclear() pt3dadd(-29, 30, 0, 1) pt3dadd(-59, 30, 0, 1)}
axon {pt3dclear() pt3dadd(-59, 30, 0, 1) pt3dadd(-119, 30, 0, 1)}
axoD {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(-29, 60, 0, 1)}
axoD[1] {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(0, 75, 0, 1)}
axoD[2] {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(30, 60, 0, 1)}
axoD[3] {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(30, 30, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(-29, 60, 0, 1) pt3dadd(-29, 90, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(-29, 60, 0, 1) pt3dadd(-59, 75, 0, 1)}
nABD {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(60, 15, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(45, -44, 0, 1)}
nABD[2] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(0, -59, 0, 1)}
nABD[3] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(-29, -14, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(60, 15, 0, 1) pt3dadd(75, 45, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(60, 15, 0, 1) pt3dadd(90, 15, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(90, 15, 0, 1) pt3dadd(105, 45, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(90, 15, 0, 1) pt3dadd(120, 0, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(0, -59, 0, 1) pt3dadd(15, -89, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(0, -59, 0, 1) pt3dadd(-29, -74, 0, 1)}
nABD_sec[6] {pt3dclear() pt3dadd(15, -89, 0, 1) pt3dadd(0, -119, 0, 1)}
nABD_sec[7] {pt3dclear() pt3dadd(15, -89, 0, 1) pt3dadd(30, -119, 0, 1)}
nABD_sec[8] {pt3dclear() pt3dadd(-29, -74, 0, 1) pt3dadd(-59, -74, 0, 1)}
nABD_sec[9] {pt3dclear() pt3dadd(-29, -74, 0, 1) pt3dadd(-44, -104, 0, 1)}
nABD_sec[10] {pt3dclear() pt3dadd(-29, -14, 0, 1) pt3dadd(-59, 0, 0, 1)}
nABD_sec[11] {pt3dclear() pt3dadd(-29, -14, 0, 1) pt3dadd(-59, -29, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
ABD all.append()
axonstart all.append()
AIS all.append()
axon all.append()
for i=0, 3 axoD[i] all.append()
for i=0, 1 axoD_sec[i] all.append()
for i=0, 3 nABD[i] all.append()
for i=0, 11 nABD_sec[i] all.append()
all_biophys = new SectionList()
ABD all_biophys.append()
axonstart all_biophys.append()
for i=0, 3 axoD[i] all_biophys.append()
for i=0, 1 axoD_sec[i] all_biophys.append()
for i=0, 3 nABD[i] all_biophys.append()
for i=0, 11 nABD_sec[i] all_biophys.append()
all_ABD=new SectionList()
ABD all_ABD.append()
axonstart all_ABD.append()
for i=0, 3 axoD[i] all_ABD.append()
for i=0, 1 axoD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 33 }
ABD { L = 23 }
axonstart { L = 19 }
AIS { L = 29.4 }
axon { L = 800 }
axoD { L = 14 }
axoD[1] { L = 80 }
axoD[2] { L = 55 }
axoD[3] { L = 138 }
axoD_sec { L = 175 }
axoD_sec[1] { L = 265 }
nABD { L = 25 }
nABD[1] { L = 446 }
nABD[2] { L = 4 }
nABD[3] { L = 74 }
nABD_sec { L = 8 }
nABD_sec[1] { L = 13 }
nABD_sec[2] { L = 22 }
nABD_sec[3] { L = 13 }
nABD_sec[4] { L = 35 }
nABD_sec[5] { L = 70 }
nABD_sec[6] { L = 83 }
nABD_sec[7] { L = 267 }
nABD_sec[8] { L = 48 }
nABD_sec[9] { L = 316 }
nABD_sec[10] { L = 80 }
nABD_sec[11] { L = 100 }
// nseg definition has to be launched before diam definition for tapering to be taken into account
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10 }
ABD { diam(0:1) = 2.4:2.7 }
axonstart { diam(0:1) = 1.3:1.2 }
AIS { diam(0:1) = 1.2:0.75 }
axon { diam = 0.75 }
axoD { diam(0:1) = 2.2:2 }
axoD[1] { diam(0:1) = 1:0.8 }
axoD[2] { diam(0:1) = 0.9:0.8 }
axoD[3] { diam(0:1) = 1.2:0.8 }
axoD_sec { diam(0:1) = 1:0.8 }
axoD_sec[1] { diam(0:1) = 1:0.8 }
nABD { diam(0:1) = 3.5:3 }
nABD[1] { diam(0:1) = 1.6:0.8 }
nABD[2] { diam(0:1) = 4.3:4 }
nABD[3] { diam(0:1) = 2.2:2 }
nABD_sec { diam = 1 }
nABD_sec[1] { diam(0:1) = 2:1 }
nABD_sec[2] { diam = 0.8 }
nABD_sec[3] { diam = 0.8 }
nABD_sec[4] { diam(0:1) = 2:1.5 }
nABD_sec[5] { diam(0:1) = 2:1.5 }
nABD_sec[6] { diam = 0.8}
nABD_sec[7] { diam(0:1) = 1:0.8 }
nABD_sec[8] { diam = 0.8 }
nABD_sec[9] { diam(0:1) = 1:0.8 }
nABD_sec[10] { diam(0:1) = 1 :0.8 }
nABD_sec[11] { diam(0:1) = 1:0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
forsec all_biophys {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
AIS {
insert kdrDA
gbar_kdrDA = 4000
insert Na12
gbar_Na12 = 4000
}
axon {
insert kdrDA
gbar_kdrDA = 400
insert Na12
gbar_Na12 = 400
}
forsec all {ena=60
ek=-90}
}
access soma
celldef()