proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD[3], nABD[2], interD[2], nABD_sec[20], interD_sec[2], axoD
create axonstart, axoD_sec[6], AIS, axon
proc topol() { local i
connect ABD(0), soma(0)
for i = 1, 2 connect ABD[i](0), ABD[i-1](1)
for i = 0, 1 connect nABD[i](0), soma(1)
for i = 0, 1 connect interD[i](0), ABD[i](1)
for i = 0, 1 connect nABD_sec[i](0), nABD(1)
for i = 2, 3 connect nABD_sec[i](0), nABD[1](1)
for i = 4, 5 connect nABD_sec[i](0), nABD_sec(1)
for i = 6, 7 connect nABD_sec[i](0), nABD_sec[2](1)
for i = 8, 9 connect nABD_sec[i](0), nABD_sec[3](1)
for i = 10, 11 connect nABD_sec[i](0), nABD_sec[4](1)
for i = 12, 13 connect nABD_sec[i](0), nABD_sec[6](1)
for i = 14, 15 connect nABD_sec[i](0), nABD_sec[8](1)
for i = 16, 17 connect nABD_sec[i](0), nABD_sec[12](1)
for i = 18, 19 connect nABD_sec[i](0), nABD_sec[15](1)
for i = 0, 1 connect interD_sec[i](0), interD[1](1)
connect axoD(0), ABD[2](1)
connect axonstart(0), ABD[2](1)
for i = 0, 1 connect axoD_sec[i](0), axoD(1)
for i = 2, 3 connect axoD_sec[i](0), axoD_sec(1)
for i = 4, 5 connect axoD_sec[i](0), axoD_sec[2](1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
basic_shape()
}
proc shape3d_1() {
soma {pt3dclear()
pt3dadd(0, 0, 0, 1)
pt3dadd(15, 0, 0, 1)
}
ABD {pt3dclear()
pt3dadd(0, 0, 0, 1)
pt3dadd(-29, 15, 0, 1)
}
nABD {pt3dclear()
pt3dadd(15, 0, 0, 1)
pt3dadd(15, -29, 0, 1)
}
nABD[1] {pt3dclear()
pt3dadd(15, 0, 0, 1)
pt3dadd(45, 0, 0, 1)
}
interD {pt3dclear()
pt3dadd(-29, 15, 0, 1)
pt3dadd(-59, 0, 0, 1)
}
ABD[1] {pt3dclear()
pt3dadd(-29, 15, 0, 1)
pt3dadd(-44, 45, 0, 1)
}
nABD_sec {pt3dclear()
pt3dadd(15, -29, 0, 1)
pt3dadd(-14, -44, 0, 1)
}
nABD_sec[1] {pt3dclear()
pt3dadd(15, -29, 0, 1)
pt3dadd(45, -44, 0, 1)
}
nABD_sec[2] {pt3dclear()
pt3dadd(45, 0, 0, 1)
pt3dadd(75, -14, 0, 1)
}
nABD_sec[3] {pt3dclear()
pt3dadd(45, 0, 0, 1)
pt3dadd(60, 30, 0, 1)
}
interD[1] {pt3dclear()
pt3dadd(-44, 45, 0, 1)
pt3dadd(-74, 45, 0, 1)
}
ABD[2] {pt3dclear()
pt3dadd(-44, 45, 0, 1)
pt3dadd(-44, 75, 0, 1)
}
nABD_sec[4] {pt3dclear()
pt3dadd(-14, -44, 0, 1)
pt3dadd(-59, -59, 0, 1)
}
nABD_sec[5] {pt3dclear()
pt3dadd(-14, -44, 0, 1)
pt3dadd(-14, -74, 0, 1)
}
nABD_sec[6] {pt3dclear()
pt3dadd(75, -14, 0, 1)
pt3dadd(105, -29, 0, 1)
}
nABD_sec[7] {pt3dclear()
pt3dadd(75, -14, 0, 1)
pt3dadd(105, 0, 0, 1)
}
nABD_sec[8] {pt3dclear()
pt3dadd(60, 30, 0, 1)
pt3dadd(90, 45, 0, 1)
}
nABD_sec[9] {pt3dclear()
pt3dadd(60, 30, 0, 1)
pt3dadd(60, 60, 0, 1)
}
interD_sec {pt3dclear()
pt3dadd(-74, 45, 0, 1)
pt3dadd(-104, 30, 0, 1)
}
interD_sec[1] {pt3dclear()
pt3dadd(-74, 45, 0, 1)
pt3dadd(-104, 60, 0, 1)
}
axoD {pt3dclear()
pt3dadd(-44, 75, 0, 1)
pt3dadd(-44, 105, 0, 1)
}
axonstart {pt3dclear()
pt3dadd(-44, 75, 0, 1)
pt3dadd(-14, 75, 0, 1)
}
nABD_sec[10] {pt3dclear()
pt3dadd(-59, -59, 0, 1)
pt3dadd(-89, -59, 0, 1)
}
nABD_sec[11] {pt3dclear()
pt3dadd(-59, -59, 0, 1)
pt3dadd(-59, -89, 0, 1)
}
nABD_sec[12] {pt3dclear()
pt3dadd(105, -29, 0, 1)
pt3dadd(105, -59, 0, 1)
}
nABD_sec[13] {pt3dclear()
pt3dadd(105, -29, 0, 1)
pt3dadd(135, -29, 0, 1)
}
nABD_sec[14] {pt3dclear()
pt3dadd(90, 45, 0, 1)
pt3dadd(120, 45, 0, 1)
}
nABD_sec[15] {pt3dclear()
pt3dadd(90, 45, 0, 1)
pt3dadd(105, 75, 0, 1)
}
axoD_sec {pt3dclear()
pt3dadd(-44, 105, 0, 1)
pt3dadd(-29, 120, 0, 1)
}
axoD_sec[1] {pt3dclear()
pt3dadd(-44, 105, 0, 1)
pt3dadd(-74, 135, 0, 1)
}
AIS {pt3dclear()
pt3dadd(-14, 75, 0, 1)
pt3dadd(15, 75, 0, 1)
}
nABD_sec[16] {pt3dclear()
pt3dadd(105, -59, 0, 1)
pt3dadd(120, -89, 0, 1)
}
nABD_sec[17] {pt3dclear()
pt3dadd(105, -59, 0, 1)
pt3dadd(90, -89, 0, 1)
}
nABD_sec[18] {pt3dclear()
pt3dadd(105, 75, 0, 1)
pt3dadd(135, 90, 0, 1)
}
nABD_sec[19] {pt3dclear()
pt3dadd(105, 75, 0, 1)
pt3dadd(105, 105, 0, 1)
}
axoD_sec[2] {pt3dclear()
pt3dadd(-29, 120, 0, 1)
pt3dadd(0, 120, 0, 1)
}
axoD_sec[3] {pt3dclear()
pt3dadd(-29, 120, 0, 1)
pt3dadd(-29, 150, 0, 1)
}
axon {pt3dclear()
pt3dadd(15, 75, 0, 1)
pt3dadd(60, 75, 0, 1)
}
axoD_sec[4] {pt3dclear()
pt3dadd(0, 120, 0, 1)
pt3dadd(30, 105, 0, 1)
}
axoD_sec[5] {pt3dclear()
pt3dadd(0, 120, 0, 1)
pt3dadd(30, 135, 0, 1)
}
}
proc basic_shape() {
shape3d_1()
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
for i=0, 2 ABD[i] all.append()
for i=0, 1 nABD[i] all.append()
for i=0, 1 interD[i] all.append()
for i=0, 19 nABD_sec[i] all.append()
for i=0, 1 interD_sec[i] all.append()
axoD all.append()
axonstart all.append()
for i=0, 5 axoD_sec[i] all.append()
AIS all.append()
axon all.append()
all_biophys = new SectionList()
for i=0, 2 ABD[i] all_biophys.append()
for i=0, 1 nABD[i] all_biophys.append()
for i=0, 1 interD[i] all_biophys.append()
for i=0, 19 nABD_sec[i] all_biophys.append()
for i=0, 1 interD_sec[i] all_biophys.append()
axoD all_biophys.append()
axonstart all_biophys.append()
for i=0, 5 axoD_sec[i] all_biophys.append()
all_ABD=new SectionList()
for i=0, 2 ABD[i] all_ABD.append()
for i=0, 1 nABD[i] all.append()
for i=0, 1 interD[i] all_ABD.append()
for i=0, 1 interD_sec[i] all_ABD.append()
axoD all_ABD.append()
axonstart all_ABD.append()
for i=0, 5 axoD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 40 }
ABD { L = 42 }
nABD { L = 7 }
nABD[1] { L = 21 }
interD { L = 270 }
ABD[1] { L = 5 }
nABD_sec { L = 35 }
nABD_sec[1] { L = 321 }
nABD_sec[2] { L = 26 }
nABD_sec[3] { L = 60 }
interD[1] { L = 81 }
ABD[2] { L = 26 }
nABD_sec[4] { L = 48 }
nABD_sec[5] { L = 47 }
nABD_sec[6] { L = 26 }
nABD_sec[7] { L = 433 }
nABD_sec[8] { L = 34 }
nABD_sec[9] { L = 57 }
interD_sec { L = 32 }
interD_sec[1] { L = 348 }
axoD { L = 23 }
axonstart { L = 20.7 }
nABD_sec[10] { L = 16 }
nABD_sec[11] { L = 297 }
nABD_sec[12] { L = 23 }
nABD_sec[13] { L = 67 }
nABD_sec[14] { L = 158 }
nABD_sec[15] { L = 39 }
axoD_sec { L = 22 }
axoD_sec[1] { L = 160 }
AIS { L = 25.2 }
nABD_sec[16] { L = 124 }
nABD_sec[17] { L = 277 }
nABD_sec[18] { L = 28 }
nABD_sec[19] { L = 17 }
axoD_sec[2] { L = 69 }
axoD_sec[3] { L = 338 }
axon { L = 800 }
axoD_sec[4] { L = 97 }
axoD_sec[5] { L = 45 }
// nseg definition has to be launched before diam definition for tapering to be taken into account
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10 }
ABD { diam(0:1) = 2.5:2.2 }
nABD { diam = 2.5 }
nABD[1] { diam = 3 }
interD { diam(0:1) = 1.8:0.8 }
ABD[1] { diam = 2.2 }
nABD_sec { diam = 1.5 }
nABD_sec[1] { diam(0:1) = 1:0.8 }
nABD_sec[2] { diam = 2 }
nABD_sec[3] { diam = 2 }
interD[1] { diam(0:1) = 1.4:1 }
ABD[2] { diam = 2.2 }
nABD_sec[4] { diam = 1 }
nABD_sec[5] { diam = 1 }
nABD_sec[6] { diam = 1 }
nABD_sec[7] { diam(0:1) = 1:0.8 }
nABD_sec[8] { diam = 1 }
nABD_sec[9] { diam = 1 }
interD_sec { diam = 0.8 }
interD_sec[1] { diam(0:1) = 1:0.8 }
axoD { diam = 1.7 }
axonstart { diam(0:1) = 1.4:0.9 }
nABD_sec[10] { diam = 0.8 }
nABD_sec[11] { diam = 0.8 }
nABD_sec[12] { diam = 1 }
nABD_sec[13] { diam = 0.8 }
nABD_sec[14] { diam = 0.8}
nABD_sec[15] { diam = 1 }
axoD_sec { diam = 1.5 }
axoD_sec[1] { diam = 0.8 }
AIS { diam(0:1) = 0.9:0.52 }
nABD_sec[16] { diam = 0.8 }
nABD_sec[17] { diam = 0.8 }
nABD_sec[18] { diam = 0.8 }
nABD_sec[19] { diam = 0.8}
axoD_sec[2] { diam = 1 }
axoD_sec[3] { diam(0:1) = 1:0.8 }
axon { diam = 0.52 }
axoD_sec[4] { diam = 0.8 }
axoD_sec[5] { diam = 0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
forsec all_biophys {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
AIS {
insert kdrDA
gbar_kdrDA = 4000
insert Na12
gbar_Na12 = 4000
}
axon {
insert kdrDA
gbar_kdrDA = 400
insert Na12
gbar_Na12 = 400
}
forsec all { ek=-90
ena=60 }
}
access soma
celldef()