proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD, axonstart, AIS, axon, axoD[2], axoD_sec[22]
create nABD[2], nABD_sec[14]
proc topol() { local i
connect ABD(0), soma(0)
connect axonstart(0), ABD(1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
for i = 0, 1 connect axoD[i](0), ABD(1)
for i = 0, 1 connect axoD_sec[i](0), axoD(1)
for i = 2, 3 connect axoD_sec[i](0), axoD_sec(1)
connect axoD_sec[4](0), axoD_sec[1](1)
for i = 5, 6 connect axoD_sec[i](0), axoD_sec[4](1)
connect axoD_sec[7](0), axoD_sec[1](1)
for i = 8, 9 connect axoD_sec[i](0), axoD_sec[7](1)
for i = 10, 11 connect axoD_sec[i](0), axoD_sec[9](1)
for i = 12, 13 connect axoD_sec[i](0), axoD_sec[11](1)
for i = 14, 15 connect axoD_sec[i](0), axoD[1](1)
for i = 16, 17 connect axoD_sec[i](0), axoD_sec[15](1)
for i = 18, 19 connect axoD_sec[i](0), axoD_sec[17](1)
for i = 20, 21 connect axoD_sec[i](0), axoD_sec[14](1)
for i = 0, 1 connect nABD[i](0), soma(1)
for i = 0, 1 connect nABD_sec[i](0), nABD(1)
for i = 2, 3 connect nABD_sec[i](0), nABD[1](1)
for i = 4, 5 connect nABD_sec[i](0), nABD_sec[3](1)
for i = 6, 7 connect nABD_sec[i](0), nABD_sec[5](1)
for i = 8, 9 connect nABD_sec[i](0), nABD_sec[7](1)
for i = 10, 11 connect nABD_sec[i](0), nABD_sec[4](1)
for i = 12, 13 connect nABD_sec[i](0), nABD_sec[11](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(15, 0, 0, 1)}
ABD {pt3dclear() pt3dadd(0, 0, 0, 1) pt3dadd(-14, 30, 0, 1)}
axonstart {pt3dclear() pt3dadd(-14, 30, 0, 1) pt3dadd(-29, 15, 0, 1)}
AIS {pt3dclear() pt3dadd(-29, 15, 0, 1) pt3dadd(-44, 0, 0, 1)}
axon {pt3dclear() pt3dadd(-44, 0, 0, 1) pt3dadd(-104, -59, 0, 1)}
axoD {pt3dclear() pt3dadd(-14, 30, 0, 1) pt3dadd(-44, 45, 0, 1)}
axoD[1] {pt3dclear() pt3dadd(-14, 30, 0, 1) pt3dadd(0, 60, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(-44, 45, 0, 1) pt3dadd(-44, 75, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(-44, 45, 0, 1) pt3dadd(-89, 45, 0, 1)}
axoD_sec[2] {pt3dclear() pt3dadd(-44, 75, 0, 1) pt3dadd(-59, 90, 0, 1)}
axoD_sec[3] {pt3dclear() pt3dadd(-44, 75, 0, 1) pt3dadd(-29, 90, 0, 1)}
axoD_sec[4] {pt3dclear() pt3dadd(-89, 45, 0, 1) pt3dadd(-104, 30, 0, 1)}
axoD_sec[5] {pt3dclear() pt3dadd(-104, 30, 0, 1) pt3dadd(-104, 0, 0, 1)}
axoD_sec[6] {pt3dclear() pt3dadd(-104, 30, 0, 1) pt3dadd(-134, 15, 0, 1)}
axoD_sec[7] {pt3dclear() pt3dadd(-89, 45, 0, 1) pt3dadd(-104, 60, 0, 1)}
axoD_sec[8] {pt3dclear() pt3dadd(-104, 60, 0, 1) pt3dadd(-134, 60, 0, 1)}
axoD_sec[9] {pt3dclear() pt3dadd(-104, 60, 0, 1) pt3dadd(-104, 90, 0, 1)}
axoD_sec[10] {pt3dclear() pt3dadd(-104, 90, 0, 1) pt3dadd(-119, 105, 0, 1)}
axoD_sec[11] {pt3dclear() pt3dadd(-104, 90, 0, 1) pt3dadd(-89, 105, 0, 1)}
axoD_sec[12] {pt3dclear() pt3dadd(-89, 105, 0, 1) pt3dadd(-89, 135, 0, 1)}
axoD_sec[13] {pt3dclear() pt3dadd(-89, 105, 0, 1) pt3dadd(-59, 120, 0, 1)}
axoD_sec[14] {pt3dclear() pt3dadd(0, 60, 0, 1) pt3dadd(0, 90, 0, 1)}
axoD_sec[15] {pt3dclear() pt3dadd(0, 60, 0, 1) pt3dadd(30, 75, 0, 1)}
axoD_sec[16] {pt3dclear() pt3dadd(30, 75, 0, 1) pt3dadd(30, 105, 0, 1)}
axoD_sec[17] {pt3dclear() pt3dadd(30, 75, 0, 1) pt3dadd(60, 75, 0, 1)}
axoD_sec[18] {pt3dclear() pt3dadd(60, 75, 0, 1) pt3dadd(75, 90, 0, 1)}
axoD_sec[19] {pt3dclear() pt3dadd(60, 75, 0, 1) pt3dadd(75, 60, 0, 1)}
axoD_sec[20] {pt3dclear() pt3dadd(0, 90, 0, 1) pt3dadd(15, 105, 0, 1)}
axoD_sec[21] {pt3dclear() pt3dadd(0, 90, 0, 1) pt3dadd(-14, 105, 0, 1)}
nABD {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(60, 15, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(15, 0, 0, 1) pt3dadd(0, -44, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(60, 15, 0, 1) pt3dadd(75, 30, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(60, 15, 0, 1) pt3dadd(90, 0, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(0, -44, 0, 1) pt3dadd(-29, -44, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(0, -44, 0, 1) pt3dadd(0, -74, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(0, -74, 0, 1) pt3dadd(-29, -89, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(0, -74, 0, 1) pt3dadd(30, -89, 0, 1)}
nABD_sec[6] {pt3dclear() pt3dadd(30, -89, 0, 1) pt3dadd(30, -119, 0, 1)}
nABD_sec[7] {pt3dclear() pt3dadd(30, -89, 0, 1) pt3dadd(60, -89, 0, 1)}
nABD_sec[8] {pt3dclear() pt3dadd(60, -89, 0, 1) pt3dadd(75, -74, 0, 1)}
nABD_sec[9] {pt3dclear() pt3dadd(60, -89, 0, 1) pt3dadd(75, -104, 0, 1)}
nABD_sec[10] {pt3dclear() pt3dadd(-29, -89, 0, 1) pt3dadd(-29, -119, 0, 1)}
nABD_sec[11] {pt3dclear() pt3dadd(-29, -89, 0, 1) pt3dadd(-59, -104, 0, 1)}
nABD_sec[12] {pt3dclear() pt3dadd(-59, -104, 0, 1) pt3dadd(-59, -134, 0, 1)}
nABD_sec[13] {pt3dclear() pt3dadd(-59, -104, 0, 1) pt3dadd(-89, -89, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys,all_ABD
all = new SectionList()
soma all.append()
ABD all.append()
axonstart all.append()
AIS all.append()
axon all.append()
for i=0, 1 axoD[i] all.append()
for i=0, 21 axoD_sec[i] all.append()
for i=0, 1 nABD[i] all.append()
for i=0, 13 nABD_sec[i] all.append()
all_biophys = new SectionList()
ABD all_biophys.append()
axonstart all_biophys.append()
for i=0, 1 axoD[i] all_biophys.append()
for i=0, 21 axoD_sec[i] all_biophys.append()
for i=0, 1 nABD[i] all_biophys.append()
for i=0, 13 nABD_sec[i] all_biophys.append()
all_ABD= new SectionList()
ABD all_ABD.append()
axonstart all_ABD.append()
for i=0, 1 axoD[i] all_ABD.append()
for i=0, 21 axoD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 19 }
ABD { L = 11 }
axonstart { L = 24.2 }
AIS { L = 27.2 }
axon { L = 800 }
axoD { L = 6 }
axoD[1] { L = 39 }
axoD_sec { L = 122 }
axoD_sec[1] { L = 11 }
axoD_sec[2] { L = 23 }
axoD_sec[3] { L = 58 }
axoD_sec[4] { L = 52 }
axoD_sec[5] { L = 123 }
axoD_sec[6] { L = 43 }
axoD_sec[7] { L = 24 }
axoD_sec[8] { L = 263 }
axoD_sec[9] { L = 11 }
axoD_sec[10] { L = 102 }
axoD_sec[11] { L = 3 }
axoD_sec[12] { L = 34 }
axoD_sec[13] { L = 21 }
axoD_sec[14] { L = 28 }
axoD_sec[15] { L = 8 }
axoD_sec[16] { L = 68 }
axoD_sec[17] { L = 145 }
axoD_sec[18] { L = 71 }
axoD_sec[19] { L = 173 }
axoD_sec[20] { L = 146 }
axoD_sec[21] { L = 245 }
nABD { L = 15 }
nABD[1] { L = 13 }
nABD_sec { L = 26 }
nABD_sec[1] { L = 10 }
nABD_sec[2] { L = 321 }
nABD_sec[3] { L = 27 }
nABD_sec[4] { L = 23 }
nABD_sec[5] { L = 30 }
nABD_sec[6] { L = 35 }
nABD_sec[7] { L = 19 }
nABD_sec[8] { L = 219 }
nABD_sec[9] { L = 54 }
nABD_sec[10] { L = 26 }
nABD_sec[11] { L = 22 }
nABD_sec[12] { L = 221 }
nABD_sec[13] { L = 111 }
// nseg definition has to be launched before diam definition for tapering to be taken into account
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10 }
ABD { diam(0:1) = 2.2:2.1 }
axonstart { diam(0:1) = 1.35:1.13 }
AIS { diam(0:1) = 1.13:0.5 }
axon { diam = 0.5 }
axoD { diam = 1.7}
axoD[1] { diam(0:1) = 1.7:1.5 }
axoD_sec { diam = 1 }
axoD_sec[1] { diam = 1.5 }
axoD_sec[2] { diam = 0.8 }
axoD_sec[3] { diam = 0.8 }
axoD_sec[4] { diam = 1 }
axoD_sec[5] { diam = 0.8 }
axoD_sec[6] { diam = 0.8 }
axoD_sec[7] { diam = 1.5 }
axoD_sec[8] { diam = 0.8 }
axoD_sec[9] { diam = 1.5 }
axoD_sec[10] { diam = 0.8 }
axoD_sec[11] { diam = 1.5 }
axoD_sec[12] { diam = 0.8 }
axoD_sec[13] { diam = 0.8 }
axoD_sec[14] { diam = 1 }
axoD_sec[15] { diam = 1 }
axoD_sec[16] { diam = 0.8 }
axoD_sec[17] { diam = 1 }
axoD_sec[18] { diam = 0.8 }
axoD_sec[19] { diam = 0.8 }
axoD_sec[20] { diam = 0.8 }
axoD_sec[21] { diam = 0.8 }
nABD { diam(0:1) = 1.7:1.5 }
nABD[1] { diam(0:1) = 5.5:5 }
nABD_sec { diam = 0.8 }
nABD_sec[1] { diam = 0.8 }
nABD_sec[2] { diam(0:1) = 2:0.8 }
nABD_sec[3] { diam(0:1) = 3:2.5 }
nABD_sec[4] { diam(0:1) = 1.5:1 }
nABD_sec[5] { diam = 1.5 }
nABD_sec[6] { diam = 0.8 }
nABD_sec[7] { diam = 1 }
nABD_sec[8] { diam = 0.8 }
nABD_sec[9] { diam = 0.8 }
nABD_sec[10] { diam(0:1) = 1:0.8 }
nABD_sec[11] { diam = 1 }
nABD_sec[12] { diam = 0.8 }
nABD_sec[13] { diam = 0.8 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
forsec all_biophys {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
AIS {
insert kdrDA
gbar_kdrDA = 4000
insert Na12
gbar_Na12 = 4000
}
axon {
insert kdrDA
gbar_kdrDA = 400
insert Na12
gbar_Na12 = 400
}
forsec all { ek=-90
ena=60 }
}
access soma
celldef()