proc celldef() {
topol()
subsets()
geom()
biophys()
// geom_nseg()
}
create soma, ABD, axonstart, AIS, axon, axoD, axoD_sec[10]
create nABD[4], nABD_sec[6]
proc topol() { local i
connect ABD(0), soma(1)
connect axonstart(0), ABD(1)
connect AIS(0), axonstart(1)
connect axon(0), AIS(1)
connect axoD(0), ABD(1)
connect axoD_sec(0), axoD(1)
for i = 1, 2 connect axoD_sec[i](0), axoD_sec(1)
connect axoD_sec[3](0), axoD(1)
for i = 4, 5 connect axoD_sec[i](0), axoD_sec[3](1)
for i = 6, 7 connect axoD_sec[i](0), axoD_sec[5](1)
for i = 8, 9 connect axoD_sec[i](0), axoD_sec[7](1)
for i = 0, 3 connect nABD[i](0), soma(0)
for i = 0, 1 connect nABD_sec[i](0), nABD[1](1)
for i = 2, 3 connect nABD_sec[i](0), nABD_sec[1](1)
for i = 4, 5 connect nABD_sec[i](0), nABD[3](1)
basic_shape()
}
proc basic_shape() {
soma {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(15, 30, 0, 1)}
ABD {pt3dclear() pt3dadd(15, 30, 0, 1) pt3dadd(30, 0, 0, 1)}
axonstart {pt3dclear() pt3dadd(30, 0, 0, 1) pt3dadd(15, -14, 0, 1)}
AIS {pt3dclear() pt3dadd(15, -14, 0, 1) pt3dadd(0, -29, 0, 1)}
axon {pt3dclear() pt3dadd(0, -29, 0, 1) pt3dadd(-29, -59, 0, 1)}
axoD {pt3dclear() pt3dadd(30, 0, 0, 1) pt3dadd(60, -14, 0, 1)}
axoD_sec {pt3dclear() pt3dadd(60, -14, 0, 1) pt3dadd(90, 0, 0, 1)}
axoD_sec[1] {pt3dclear() pt3dadd(90, 0, 0, 1) pt3dadd(105, 15, 0, 1)}
axoD_sec[2] {pt3dclear() pt3dadd(90, 0, 0, 1) pt3dadd(105, -14, 0, 1)}
axoD_sec[3] {pt3dclear() pt3dadd(60, -14, 0, 1) pt3dadd(75, -44, 0, 1)}
axoD_sec[4] {pt3dclear() pt3dadd(75, -44, 0, 1) pt3dadd(90, -59, 0, 1)}
axoD_sec[5] {pt3dclear() pt3dadd(75, -44, 0, 1) pt3dadd(75, -74, 0, 1)}
axoD_sec[6] {pt3dclear() pt3dadd(75, -74, 0, 1) pt3dadd(75, -104, 0, 1)}
axoD_sec[7] {pt3dclear() pt3dadd(75, -74, 0, 1) pt3dadd(45, -89, 0, 1)}
axoD_sec[8] {pt3dclear() pt3dadd(45, -89, 0, 1) pt3dadd(15, -74, 0, 1)}
axoD_sec[9] {pt3dclear() pt3dadd(45, -89, 0, 1) pt3dadd(15, -104, 0, 1)}
nABD {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(-14, 0, 0, 1)}
nABD[1] {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(-29, 30, 0, 1)}
nABD[2] {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(0, 75, 0, 1)}
nABD[3] {pt3dclear() pt3dadd(0, 30, 0, 1) pt3dadd(30, 60, 0, 1)}
nABD_sec {pt3dclear() pt3dadd(-29, 30, 0, 1) pt3dadd(-29, 60, 0, 1)}
nABD_sec[1] {pt3dclear() pt3dadd(-29, 30, 0, 1) pt3dadd(-59, 15, 0, 1)}
nABD_sec[2] {pt3dclear() pt3dadd(-59, 15, 0, 1) pt3dadd(-74, 30, 0, 1)}
nABD_sec[3] {pt3dclear() pt3dadd(-59, 15, 0, 1) pt3dadd(-74, 0, 0, 1)}
nABD_sec[4] {pt3dclear() pt3dadd(30, 60, 0, 1) pt3dadd(30, 90, 0, 1)}
nABD_sec[5] {pt3dclear() pt3dadd(30, 60, 0, 1) pt3dadd(60, 60, 0, 1)}
}
objref all, all_biophys, all_ABD
proc subsets() { local i
objref all, all_biophys, all_ABD
all = new SectionList()
soma all.append()
ABD all.append()
axonstart all.append()
AIS all.append()
axon all.append()
axoD all.append()
for i=0, 9 axoD_sec[i] all.append()
for i=0, 3 nABD[i] all.append()
for i=0, 5 nABD_sec[i] all.append()
all_biophys = new SectionList()
ABD all_biophys.append()
axonstart all_biophys.append()
axoD all_biophys.append()
for i=0, 9 axoD_sec[i] all_biophys.append()
for i=0, 3 nABD[i] all_biophys.append()
for i=0, 5 nABD_sec[i] all_biophys.append()
all_ABD=new SectionList()
ABD all_ABD.append()
axonstart all_ABD.append()
axoD all_ABD.append()
for i=0, 9 axoD_sec[i] all_ABD.append()
}
proc geom() {
soma { L = 18}
ABD { L = 14 }
axonstart { L = 21.7 }
AIS { L = 26.3 }
axon { L = 800 }
axoD { L = 24 }
axoD_sec { L = 83 }
axoD_sec[1] { L = 112 }
axoD_sec[2] { L = 25 }
axoD_sec[3] { L = 220 }
axoD_sec[4] { L = 27 }
axoD_sec[5] { L = 35 }
axoD_sec[6] { L = 90 }
axoD_sec[7] { L = 146 }
axoD_sec[8] { L = 6 }
axoD_sec[9] { L = 19 }
nABD { L = 402 }
nABD[1] { L = 34 }
nABD[2] { L = 21 }
nABD[3] { L = 28 }
nABD_sec { L = 277 }
nABD_sec[1] { L = 11 }
nABD_sec[2] { L = 120 }
nABD_sec[3] { L = 344 }
nABD_sec[4] { L = 396 }
nABD_sec[5] { L = 20 }
// nseg definition has to be launched before diam definition for tapering to be taken into account
forsec all { nseg = int((L/(0.1*lambda_f(1000))+.999)/2)*2 + 1 }
soma { diam = 10}
ABD { diam(0:1) = 2.7:3 }
axonstart { diam(0:1) = 1.7:1.35 }
AIS { diam(0:1) = 1.35:0.6 }
axon { diam = 0.6 }
axoD { diam(0:1) = 2.1:2 }
axoD_sec { diam = 1 }
axoD_sec[1] { diam = 0.8 }
axoD_sec[2] { diam = 0.8 }
axoD_sec[3] { diam(0:1) = 1.5:1 }
axoD_sec[4] { diam = 0.8 }
axoD_sec[5] { diam = 1 }
axoD_sec[6] { diam = 0.8 }
axoD_sec[7] { diam(0:1) = 1 :0.8 }
axoD_sec[8] { diam =0.8 }
axoD_sec[9] { diam = 0.8 }
nABD { diam(0:1) = 2:0.8 }
nABD[1] { diam(0:1) = 3:2 }
nABD[2] { diam(0:1) = 1.5:1 }
nABD[3] { diam(0:1) = 3.2:3 }
nABD_sec { diam(0:1) = 1:0.8 }
nABD_sec[1] { diam = 1.5 }
nABD_sec[2] { diam =0.8 }
nABD_sec[3] { diam(0:1) = 1:0.8 }
nABD_sec[4] { diam(0:1) = 1.5:0.8 }
nABD_sec[5] { diam(0:1) = 1.5:1 }
}
proc biophys() {
forsec all {
Ra = 150
cm = 0.75
insert pasnts
g_pasnts = 1e-05
e_pasnts = -50
}
forsec all_biophys {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDa
gbar_kaDa = 50
taurecov_kaDa = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
soma {
insert CAV13
gbar_CAV13 = 1.25
iLCa_CAV13 = 0
insert Ih
gbar_Ih = 3
insert kaDasoma
gbar_kaDasoma = 150
taurecov_kaDasoma = 25
insert kdrDA
gbar_kdrDA = 150
insert Na12
gbar_Na12 = 75
insert cad
insert kca
gbar_kca = 0.1
}
AIS {
insert kdrDA
gbar_kdrDA = 4000
insert Na12
gbar_Na12 = 4000
}
axon {
insert kdrDA
gbar_kdrDA = 400
insert Na12
gbar_Na12 = 400
}
forsec all { ek=-90
ena=60 }
}
access soma
celldef()