TITLE KRP channel
COMMENT
Unit check passed even without Units off
ENDCOMMENT
NEURON {
SUFFIX KRP
USEION k READ ek WRITE ik
RANGE g, gmax, ik
GLOBAL minf, mtau, hinf, htau
}
UNITS {
(mA) = (milliamp)
(uA) = (microamp)
(mV) = (millivolt)
(mS) = (millimho)
}
PARAMETER {
gmax = 0.001 (mho/cm2) <0,1e9>
ek (mV)
m_vh = -13.5 (mV) : half activation
m_ve = -11.8 (mV) : slope
h_vh = -54.7 (mV) : half activation
h_ve = 18.6 (mV) : slope
}
ASSIGNED {
v (mV)
g (mho/cm2)
ik (mA/cm2)
minf (1)
hinf (1)
mtau (ms)
htau (ms)
}
CONSTANT {
a = 0.7 (1)
}
STATE {
m
h
}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gmax*m*(a*h+(1-a))
ik = g*(v - ek)
}
INITIAL {
rates(v)
m = minf
h = hinf
}
DERIVATIVE states {
rates(v)
m' = (minf-m)/mtau
h' = (hinf-h)/htau
}
FUNCTION_TABLE tabmtau(v(mV)) (ms)
FUNCTION_TABLE tabhtau(v(mV)) (ms)
: rates() computes rate and other constants at present v
: call once from hoc to initialize inf at resting v
PROCEDURE rates(v(mV)) {
: TABLE minf, hinf FROM -120 TO 30 WITH 70
mtau = tabmtau(v)
minf = 1/(1 + exp((v - m_vh)/m_ve))
htau = tabhtau(v)
hinf = 1/(1 + exp((v - h_vh)/h_ve))
}