//genesis // AddCaSpines.g /*************************** MS Model, Version 7.6 ********************* **************************** AddCaSpines.g ********************* Avrama Blackwell kblackw1@gmu.edu Rebekah Evans rcolema2@gmu.edu Tom Sheehan tsheeha2@gmu.edu ****************************************************************************** *****************************************************************************/ //function to add calcium channels to spines function addCaChannelspines(channelName, compPath, conductance, caBufferName) str channelName, compPath float conductance str caBufferName pushe {compPath} // Copy the channel from library copy /library/{channelName} {channelName} copy /library/{channelName}GHK {channelName}GHK // Set the new conductance float len = {getfield {compPath} len} float dia = {getfield {compPath} dia} float pi = 3.141592653589793 float surf = {len*dia*pi} // echo "Channel: "{channelName}", conductance "{conductance}"S/m²" // echo "Compartment: "{compPath}", surface area "{surf}"m²" setfield {channelName} Gbar {conductance*surf} // Couple channel to caBuffer coupleCaBufferCaChannel {caBufferName} {compPath} {channelName} // Couple channel, its GHK object and compartment together addmsg {compPath} {channelName}GHK VOLTAGE Vm addmsg {compPath} {channelName} VOLTAGE Vm addmsg {channelName}GHK {compPath} CHANNEL Gk Ek addmsg {channelName} {channelName}GHK PERMEABILITY Gk // float len = {getfield {compPath} len} // float dia = {getfield {compPath} dia} // float pi = 3.141592653589793 // float surf = {len*dia*pi} // // echo "conductance (unscaled): "{conductance} // // echo "Compartment: "{compPath}" surface area "{surf}"m²" // setfield {channelName} Gbar {conductance*surf} pope end