//genesis /*************************** MS Model, Version 7.6 ********************* **************************** SynParamsA.g ********************* Avrama Blackwell kblackw1@gmu.edu Rebekah Evans rcolema2@gmu.edu Tom Sheehan tsheeha2@gmu.edu ****************************************************************************** To change synaptic parameters, change the include in MScellSpine.g *****************************************************************************/ str AMPAname = "AMPA" float EkAMPA = 0.0 float AMPAtau1 = 1.1e-3 float AMPAtau2 = 5.75e-3 float AMPAgmax = 342e-12 str GABAname = "GABA" float GABAtau1 = 0.25e-3 // From Galarreta and Hestrin 1997 float GABAtau2 = 3.75e-3 //(used in Wolfs model) float EkGABA = -0.060 float GABAgmax = 750e-12 //Modified Koos 2004 int GABA2Spine = 0 // = 0, No GABA; // 1, add GABA to spine head // 2, add GABA to spine neck int addCa2Spine = 1 // 0, no ca channels in spine, //1, yes ca channels in spine (non-synaptic) int NMDABufferMode = 0 // 1, connect both NMDA and AMPA calcium to NMDA_buffer // 0, connect only NMDA currents to NMDA_buffer float useAMPANMDAGHKchannels= 0 // we do not use GHK project for NMDA/AMPA // parameters for NMDA subunits // NR2A str subunit = "NR2A" float EkNMDA = 0 float Kmg = 3.57 float NMDAtau2 = (50e-3)/2 //NR2A average from (Vicini et al., 1998 figure 1B) float NMDAgmax = 0.94e-9 //NR2A and B from (Moyner et al., 1994 figure 7) int ghk_yesno=0 str NMDAname = {subunit}