//genesis // globals.g /*************************** MS Model, Version 7.6 ********************* **************************** globals.g ********************* Avrama Blackwell kblackw1@gmu.edu Rebekah Evans rcolema2@gmu.edu Tom Sheehan tsheeha2@gmu.edu ****************************************************************************** *****************************************************************************/ float ELEAK = -0.070 float PI = 3.1415926 float RA = 1.0; float RM = 8.69565217; float CM = 0.01; float EREST_ACT = -0.085 float TEMPERATURE = 35 str CA_BUFF_1 = "Ca_difshell_1" // L and T type channels str CA_BUFF_2 = "Ca_difshell_2" // coupled to the other channels str CA_BUFF_3 = "Ca_difshell_3" // all calcium channels int CaDyeFlag = 0 // flags of calcium dye. "0" means NO calcium dyes. int shellMode = 1 // mode = 1 : simple calcium pool adopted from Sabatini's work(Sabatini, 2001, 2004) //parameters determined by hand tuning to match spike width, AHP shape &, fI curve str gNaFprox={90000} //qfactor = 1.2 str gNaFmid={2730} str gNaFdist={975} str gKAfprox={3214/4.2} //qfactor=1.5 for inact str gKAfmid={471/2.8} //1/qfactor=1.5 for act str gKAfdist={314/2.8} str gKAsprox={277*1.3} //qfactor=2 str gKAsdist={22.9*1.7} str gKIR=8 //qfactor = 0.5 str gKDR={7.25/1.2} //qfactor = 0.5 str gBK = 10 str gSK = 2 float gCaL13 = {1.5*1.0625e-7} //qfactor=2 float gCaT = {1.5*0.5875e-8} float gCaR = {1.5*6.5e-7} float gCaN = {1.5*2.5e-7} //qfactor=2 float gCaL12 = {1.5*0.8375e-7} //qfactor=2 float qfactorKDR = 0.5 float qfactorNaF =1.2 float qfactorkAs=2.5 float qfactorkAf=1.5