TITLE GKCA
: FORREST MD (2014) Two Compartment Model of the Cerebellar Purkinje Neuron
UNITS {
(molar) = (1/liter)
(pA) = (picoamp)
(mV) = (millivolt)
(S) = (siemens)
(mA) = (milliamp)
(mM) = (millimolar)
}
INDEPENDENT {v FROM -100 TO 50 WITH 50 (mV)}
NEURON {
SUFFIX gkca
USEION ca READ cai
USEION k WRITE ik
RANGE gkbar,km,oinf,n,ik
}
PARAMETER {
dt (ms)
cai (mM)
km = 0.00019 (mM)
n = 4.0
cainit = 0.000184 (mM)
celsius = 35 (degC)
gkbar = 0 (mho/cm2) : (S/cm2)
: ek = -100 (mV)
}
ASSIGNED {
ik (mA/cm2)
oinf
ek (mV)
}
BREAKPOINT {
oinf = 1/(1 + pow(km/cai,n))
ik = oinf*gkbar*(v - ek)
}
COMMENT
INITIAL{
cai = cainit}
ENDCOMMENT