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The scripts following below reproduce the simulation results presented in the manuscript:
Victor V. Matveev, Richard Bertram and Arthur Sherman (2009)
Ca2+ current vs. Ca2+ channel cooperativity of exocytosis
Journal of Neuroscience, 29(39): 12196-12209.
[ Abstract ]
[ Full Text ]
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♦ Fig1.par
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This CalC script generates the first figure of the manuscript. It requires a single command-line parameters, the
total buffer concentration (in μM) (e.g. run calc Fig1.par 100 ). The simulation
produces an ASCII data file with five columns:
(1) single-channel Ca2+ current (varied from 0.001 to 1 pA);
(2) maximal release produced by a 1ms-long
current pulse;
(3) corresponding maximal [Ca2+] at release site, 30 nm from channel;
(4) maximal volume-averaged [Ca2+];
(5) time to peak release after simulation start.
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♦ Fig1.m
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A MATLAB m-file that generates Figure 1 using data produced by CalC script Fig1.par above.
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♦ Fig7_8.par
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This CalC script generates data for Figures 7 and 8 of the manuscript. The simulation
produces an ASCII data file used by MATLAB script Fig7_8.m below.
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♦ Fig7_8.m
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A MATLAB m-file that generates Figures 7 and 8 using data produced by CalC script Fig7_8.par above.
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♦ process2D.m
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A simple MATLAB data parsing script required by MATLAB m-files and Fig1.m and Fig7_8.m .
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