TITLE Sodium transient current for Yu et al. 2008
COMMENT
Implemented by Erin Munro
ENDCOMMENT
INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) }
UNITS {
(mV) = (millivolt)
(mA) = (milliamp)
}
NEURON {
SUFFIX nafYu
USEION na READ ena WRITE ina
RANGE gbar, ina, m, h, df, am, bm, ah, bh, hinf
}
PARAMETER {
gbar = 0.0 (mho/cm2)
v (mV) ena (mV)
}
ASSIGNED {
ina (mA/cm2)
am (1/ms) bm (1/ms)
ah (1/ms) bh (1/ms)
hinf (1)
df (mV)
}
STATE {
m h
}
BREAKPOINT {
SOLVE states METHOD cnexp
ina = gbar * m * m * m * h * ( v - ena )
df = v - ena
}
INITIAL {
settables( v )
m = 0
h = hinf
}
DERIVATIVE states {
settables( v )
m' = am*( 1 - m ) - bm*m
h' = (ah+bh)*(hinf - h)
}
UNITSOFF
PROCEDURE settables(v(mV)) {
TABLE am, bm, ah, bh, hinf FROM -120 TO 40 WITH 641
am = 0.182*(v+25)/(1-exp(-(v+25)/9))
bm = -0.124*(v+25)/(1-exp((v+25)/9))
ah = 0.024*(v+40)/(1-exp(-(v+40)/5))
bh = -0.0091*(v+65)/(1-exp((v+65)/5))
hinf = 1/(1+exp((v+55)/6.2))
}
UNITSON